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Авторы трудов (статей) использованные при подготовке материалов по терапии

В статьях на сайте использованы следующие сокращения:

  • °F — температура по Фаренгейту
  • °C — температура по Цельсию
  • 5-НТ — 5-гидроксииндолуксусная кислота мочи
  • АБ — антибиотик(и)
  • АБЛА — аллергический бронхолегочный аспергиллез
  • АБТ — антибактериальная терапия
  • АВ — атриовентрикулярный
  • АГ — артериальная гипертензия
  • АГн — антиген
  • АД — артериальное давление
  • АДГ — антидиуретический гормон
  • АДС — анатоксин дифтерийно-столбнячный
  • АДС-М — анатоксин дифтерийно-столбнячный (малые дозы)
  • АДФ — аденозиндифосфорная кислота, аденозиндифосфат
  • АКДС — анатоксин коклюшно-дифтерийно-столбнячный
  • АКТГ — адренокортикотропный гормон
  • АКШ — аортокоронарное шунтирование
  • АЛТ — аланинаминотрансфераза
  • амер. — американский
  • АМК — азот мочевины крови
  • АМФ — аденозинмонофосфорная кислота, аденозинмонофосфат
  • АНА — антинуклеарные антитела
  • анат. — анатомический
  • англ. — английский
  • АНЦА — антинейтрофильные цитоплазматические антитела
  • АПФ — ангиотензин-превращающий фермент
  • АРВТ — антиретровирусная терапия
  • АРП — активность ренина в плазме крови
  • АСК — аминосалициловая кислота
  • ACT — аспартатаминотрансфераза
  • АТл — антитело
  • АТФ — аденозинтрифосфорная кислота, аденозинтрифосфат
  • АуД — аутосомно-доминантный
  • АуР — аутосомно-рецессивный
  • АФП — α-фетопротеин
  • АФС — антифосфолипидный синдром
  • АХЭ — ацетилхолинэстераза
  • АЦХ — ацетилхолин
  • АЧТВ — активированное частичное тромбопластиновое время
  • БА — бронхиальная астма
  • БАД — биологически активная добавка
  • БАЛ — бронхоальвеолярный лаваж
  • БАР — биполярное аффективное расстройство (I или II типа)
  • БКК — большой круг кровообращения
  • БЛНПГ — блокада левой ножки пучка Гиса
  • БМСЭ — бюро медико-социальной экспертизы
  • БП — брюшная полость
  • БПНПГ — блокада правой ножки пучка Гиса
  • БРА — блокатор рецепторов ангиотензина
  • БРМ — базовые реанимационные мероприятия
  • БРНС — быстро разрешившееся необъяснимое событие
  • БЦЖ — бацилла Кальметта-Герена
  • в т.ч. — в том числе
  • в. — век
  • в/ — внутри... в сложносоставных словах (напр.
  • в/сосудистый, в/черепной и т.п.)
  • в/а — внутриартериально
  • в/в — внутривенно
  • в/к — внутрикожно
  • в/м — внутримышечно
  • вв. — века
  • в-во — вещество
  • ВВЭ — военно-врачебная экспертиза
  • ВГД — внутриглазное давление
  • ВГЧ — вирус герпеса человека
  • ВДП — верхние дыхательные пути
  • ВЖК — внутрижелудочковое кровоизлияние
  • ВЗК — воспалительные заболевания кишечника
  • ВЗОМТ — воспалительные заболевания органов малого таза
  • ВИП — вазоактивный интестинальный пептид
  • ВИЧ — вирус иммунодефицита человека
  • ВМП — высокотехнологичная медицинская помощь
  • ВМС — внутриматочное средство (спираль)
  • ВН — вирусная нагрузка
  • ВНС — вегетативная нервная система
  • ВОВ — Великая Отечественная война
  • ВОГМ — высокогорный отек головного мозга
  • ВОЗ — Всемирная организация здравоохранения
  • ВОЛ — высокогорный отек легких
  • ВОМК — врач, осуществляющий медицинский контроль
  • ВОП — врач общей практики
  • ВПВ — верхняя полая вена
  • ВПГ — вирус простого герпеса
  • ВПР — врожденные пороки развития
  • ВПС — врожденный порок сердца
  • ВПЧ — вирус папилломы человека
  • ВРТ — вспомогательные репродуктивные технологии
  • ВСО — водно-солевой обмен
  • ВЧД — внутричерепное давление
  • ВЧИВЛ — высокочастотная искусственная вентиляция легких (HFV)
  • ВЭБ — вирус Эпштейна-Барр
  • г — грамм
  • г. — год
  • Г-6-ФД — глюкозо-6-фосфатдегидрогеназа
  • ГАМК — гамма-аминомасляная кислота
  • ГБ — гипертоническая болезнь
  • ГБН — гемолитическая болезнь новорожденного
  • ГБО — гипербарическая оксигенация
  • ГГПТ — γ-глутамилтранспептидаза
  • ГЗТ — гиперчувствительность замедленного типа
  • гист. — гистологический
  • ГК — грудная клетка
  • ГКМП — гипертрофическая кардиомиопатия
  • ГКС — глюкокортикостероид(ы)
  • ГЛГ — гемофагоцитарный лимфогистиоцитоз
  • ГЛПС — геморрагическая лихорадка с почечным синдромом
  • ГМ — головной мозг
  • ГМ-КСФ — гранулоцитарно-макрофагальный колониестимулирующий фактор
  • ГМФ — гуанозинмонофосфат
  • ГнРГ — гонадотропин-рилизинг-гормон
  • ГНТ — гиперчувствительность немедленного типа
  • ГПОД — грыжа пищеводного отверстия диафрагмы
  • ГРДС — гипоксическая реакция дыхательной системы
  • греч. — греческий
  • ГТФ — гуанозинтрифосфат
  • ГУС — гемолитико-уремический синдром
  • Гц — герц
  • ГЭБ — гематоэнцефалический барьер
  • ГЭР — гастроэзофагеальный рефлюкс
  • ГЭРБ — гастроэзофагеальная рефлюксная болезнь
  • дБ — децибел
  • ДВС — диссеминированное внутрисосудистое свертывание
  • ДГПЖ — доброкачественная гиперплазия предстательной железы
  • ДГТ — дигидротестостерон
  • ДД — дифференциальная диагностика, дифференциально-диагностический
  • ДДБА — длительно действующие β2-агонисты
  • ДДК — дифференциально-диагностический критерий (критерии)
  • ДИ — доверительный интервал
  • ДК — диагностический критерий
  • ДКА — диабетический кетоацидоз
  • ДКМП — дилатационная кардиомиопатия
  • ДМЖП — дефект межжелудочковой перегородки
  • ДМПП — дефект межпредсердной перегородки
  • ДМС — добровольное медицинское страхование
  • ДН — дыхательная недостаточность
  • ДНК — дезоксирибонуклеиновая кислота
  • ДНТ — дефекты нервной трубки
  • ДОФА — дигидроксифенилаланин
  • ДП — дыхательные пути
  • ДПК — двенадцатиперстная кишка
  • ДПМ — дата последней менструации
  • ДПП — давление в правом предсердии
  • др. — другие
  • ДТП — дорожно-транспортное происшествие
  • ДЦП — детский церебральный паралич
  • ЕД — единица действия
  • ЖВП — желчевыводящие пути
  • ЖДА — железодефицитная анемия
  • ЖЕЛ — жизненная емкость легких
  • ЖКБ — желчекаменная болезнь
  • ЖКК — желудочно-кишечное кровотечение
  • ЖКТ — желудочно-кишечный тракт
  • ЖНВЛП — жизненно необходимые и важные лекарственные препараты (список, перечень)
  • ЖТ — желудочковая тахикардия
  • ЗВУР — задержка внутриутробного развития
  • ЗЛ — здоровые люди (лица)
  • ЗНО — злокачественное новообразование
  • ЗО — здравоохранение
  • ЗОЖ — здоровый образ жизни
  • ЗСН — застойная сердечная недостаточность
  • иАПФ — ингибиторы ангиотензин-превращающего фермента
  • ИБС — ишемическая болезнь сердца
  • ИВЛ — искусственная вентиляция легких
  • ИГКС — ингаляционные глюкокортикостероиды
  • ИЗЛ — интерстициальные заболевания легких
  • ИКД — имплантируемый кардиовертер-дефибриллятор
  • ИКП — иммунокомпрометированные пациенты
  • ИЛ — интерлейкин
  • ИЛДБ — интегрированное лечение детских болезней
  • ИМ — инфаркт миокарда
  • ИМАО — ингибитор(ы) моноаминоксидазы
  • ИМбпБТ — инфаркт миокарда без подъема сегмента ST
  • ИМП — инфекция мочевых (мочевыводящих) путей
  • ИМпST — инфаркт миокарда с подъемом сегмента ST
  • ИМТ — индекс массы тела
  • ИОЛ — интраокулярная линза
  • ИПП — ингибиторы протонной помпы (протонного насоса)
  • ИППП — инфекции, передаваемые половым путем
  • ИСС — индивидуальные спасательные средства
  • истор. — историческое
  • итал. — итальянский
  • ИТП — идиопатическая тромбоцитопеническая пурпура
  • ИТШ — инфекционно-токсический шок
  • ИФА — иммуноферментный анализ
  • КА — коронарная(ые) артерия(и)
  • КАГ — коронарография
  • КБМП - качество и безопасность медицинской помощи
  • кВ — киловольт
  • кг — килограмм
  • КДБА — короткодействующие β2-агонисты
  • КДД — конечно-диастолическое давление
  • КДО — конечно-диастолический объем
  • КДР — конечно-диастолический размер
  • кит. — китайский
  • ккал — килокалория
  • кл. — клетки, клеток
  • КМП — качество медицинской помощи
  • КоА — коэнзим А, кофермент А
  • КОЕ — колониеобразующая единица
  • КОК — комбинированные оральные контрацептивы
  • КПТ — когнитивно-поведенческая терапия
  • КР — клинические рекомендации
  • КСД — конечно-систолическое давление
  • КСО — конечно-систолический объем
  • КСР — конечно-систолический размер
  • КТ — компьютерная томография
  • КТВР — компьютерная томография высокого разрешения
  • КТГ — кардиотокография
  • КФК — креатинфосфокиназа
  • КЩС — кислотно-щелочное состояние
  • л — литр
  • л/о — ложноотрицательный
  • л/п — ложноположительный
  • ЛА — легочная артерия
  • ЛАГ — легочная артериальная гипертензия лат. — латинский
  • ЛГ — лютеинизирующий гормон
  • ЛДГ — лактатдегидрогеназа
  • ЛЖ — левый желудочек
  • ЛОР — имеющий отношение к оториноларингологии (ЛОР-врач, ЛОР-органы)
  • ЛП — лекарственный препарат
  • ЛПВП — липопротеины высокой плотности
  • ЛПНП — липопротеины низкой плотности
  • ЛПОНП — липопротеины очень низкой плотности
  • ЛПУ — лечебно-профилактическое учреждение ЛС — лекарственное средство
  • ЛУ — лимфатический(ие) узел(лы)
  • ЛФК — лечебная физкультура
  • м.б. — может (мог, могут, могли) быть
  • М/Ж — соотношение мужчин и женщин
  • максД — максимальная доза
  • максНД — максимальная начальная доза
  • максРД — максимальная разовая доза
  • максСД — максимальная суточная доза
  • МАНК — метод амплификации нуклеиновых кислот
  • МАО — моноаминоксидаза
  • МВП — мочевыводящие пути
  • мг — миллиграмм
  • МДБ — мышечная дистрофия Беккера
  • МДД — мышечная дистрофия Дюшенна
  • МДМА — метилендиоксиметамфетамин
  • ME — международная единица
  • мед. — медицинский
  • мес — месяц
  • МЖ — молочная железа
  • МЖП — межжелудочковая перегородка
  • М3 — министерство здравоохранения
  • мин — минут(а)
  • минД — минимальная доза
  • минСД — минимальная суточная доза
  • МКБ — мочекаменная болезнь
  • МКБ-10 — Международная классификация болезней 10-го пересмотра
  • МКБ-11 —Международная классификация болезней 11-го пересмотра
  • мкВ — микровольт
  • мкг — микрограмм
  • МКК — малый круг кровообращения
  • мкл — микролитр
  • мл — миллилитр
  • млн — миллион
  • млрд — миллиард
  • мм — миллиметр
  • мм рт.ст. — миллиметр ртутного столба
  • ммоль — миллимоль
  • МНН — международное непатентованное наименование
  • МНО — международное нормализованное отношение
  • МО — медицинская организация
  • МП — медицинская помощь
  • МПС — мочеполовая система
  • МР — магнитно-резонансный
  • МР-венография — МРТ вен и синусов головного мозга мРНК — матричная РНК
  • МРТ — магнитно-резонансная томография
  • МРХПГ — магнитно-резонансная холангиопанкреатография
  • мс — миллисекунда
  • МСКТ — мультиспиральная компьютерная томогра-
  • фия
  • МСЭ — медико-социальная экспертиза
  • МТ — масса тела
  • мтДНК — митохондриальная дезоксирибонуклеиновая кислота
  • МТР — масса тела при рождении
  • н.э. — нашей эры
  • НА — нервная анорексия
  • НАД — никотинамидадениндинуклеотид
  • НАДН — никотинамидадениндинуклеотид (восстановленный)
  • НАДФ — никотинамидадениндинуклеотидфосфат
  • НАЖБП — неалкогольная жировая болезнь печени напр. — например
  • НАСГ — неалкогольный стеатогепатит
  • НБ — нервная булимия
  • НДО — негативный детский опыт
  • нед — недели
  • нем. — немецкий
  • НИВЛ — неинвазивная вентиляция легких
  • НЛР — нежелательная лекарственная реакция
  • нм — нанометр
  • НМГ — низкомолекулярный гепарин
  • НМИЦ — национальный медицинский исследовательский центр
  • НМП — неотложная медицинская помощь
  • НМТ — низкая масса тела
  • НПА — нормативно-правовой акт
  • НПВ — нижняя полая вена
  • НПВС — нестероидные противовоспалительные средства
  • НС — нервная система
  • НСГ — нейросонография
  • НЭК — некротический энтероколит
  • НЯК — неспецифический язвенный колит
  • ОАК — общий анализ крови
  • ОАМ — общий анализ мочи
  • ОАП — открытый артериальный проток
  • ОБП — органы брюшной полости
  • ОГБ — острая горная болезнь
  • ОГМ — отек головного мозга
  • ОДН — острая дыхательная недостаточность
  • ОЖСС — общая железосвязывающая способность сыворотки
  • ОЗ — организация здравоохранения
  • ок. — около
  • ОКР — обсессивно-компульсивное расстройство
  • ОКС — острый коронарный синдром
  • ОЛЛ — острый лимфобластный лейкоз
  • ОМП - оказание медицинской помощи
  • ОМС — обязательное медицинское страхование
  • ОМТ — органы малого таза
  • ОНМК — острое нарушение мозгового кровообращения
  • ОНМП — отделение неотложной (медицинской) помощи
  • ОНМТ — очень низкая масса тела
  • ООЗ — органы (организации/управления) здравоохранения
  • ООЛ — остаточный объем легких
  • ООН — Организация Объединенных Наций
  • ОПЖ — ожидаемая продолжительность жизни
  • ОПН — острая почечная недостаточность
  • ОПП — острое повреждение почек
  • ОПСС — общее периферическое сосудистое сопротивление
  • ОРВИ — острая респираторная вирусная инфекция
  • ОРДС — острый респираторный дистресс-синдром
  • ОРЗ — острое респираторное заболевание
  • ОРИТ — отделение реанимации и интенсивной терапии (ICU)
  • ОСВО — общее содержание воды в организме
  • ОФВ — объем форсированного выдоха
  • ОФВ1 — объем форсированного выдоха за 1-ю секунду
  • ОЦК — объем циркулирующей крови
  • п.з. — поле зрения (микроскопа)
  • п/к — подкожно
  • ПАВ — психоактивные вещества
  • ПВ — протромбиновое время
  • ПВК — периферический венозный катетер
  • ПВЛ — перивентрикулярная лейкомаляция
  • Пг — простагландин
  • ПГГ — программа государственных гарантий оказания гражданам РФ бесплатной медицинской помощи
  • ПДКВ — положительное давление конца выдоха (PEEP)
  • ПЖ — правый желудочек
  • ПЖЖ — поджелудочная железа
  • ПЖК — подкожная жировая клетчатка (гиподерма)
  • ПКА — почечный канальцевый ацидоз
  • ПКМД — поясно-конечностная мышечная дистрофия
  • ПЛСГ — пятнистая лихорадка Скалистых гор
  • ПМДР — предменструальное дисфорическое расстройство
  • ПМК — пролапс митрального клапана
  • ПМС — предменструальный синдром
  • ПМСП — первичная медико-санитарная помощь
  • ПНА — передняя нисходящая артерия
  • ПНЖК — полиненасыщенные жирные кислоты
  • ПОРИТ — педиатрическое отделение реанимации и интенсивной терапии
  • ПОТ — постуральная ортостатическая тахикардия
  • ППВ — пневмококковая полисахаридная вакцина
  • ППОАК — прямые пероральные антикоагулянты ППТ — площадь поверхности тела
  • ПСА — простатоспецифический антиген
  • ПСВ — пиковая скорость выдоха
  • ПСВХ — прогрессирующий семейный внутрипеченочный холестаз
  • ПТ — психотерапия
  • ПТВ — протромбиновое время
  • ПТГ — паратиреоидный гормон
  • ПТИ — протромбиновый индекс
  • ПТСР — посттравматическое стрессовое расстройство
  • ПФЭ — пищевой фолатный эквивалент
  • ПЦР — полимеразная цепная реакция
  • ПШГ — пурпура Шенлейна-Геноха
  • ПЩЖ — паращитовидные железы
  • ПЭТ — позитронно-эмиссионная томография р/ —раз в ... (с, мин, ч, сут и т.п.)
  • РА — ревматоидный артрит
  • РААС — ренин-ангиотензин-альдостероновая система
  • разг. — разговорный
  • разл. — различный
  • РАС — расстройство аутистического спектра
  • РДС — респираторный дистресс-синдром
  • рим. — римский
  • РИФ — реакция иммунофлюоресценции
  • РКИ — рандомизированные клинические исследования
  • РКМП — рестриктивная кардиомиопатия
  • РИГА — реакция непрямой гемагглютинации
  • РНК — рибонуклеиновая кислота
  • РОГК — рентгенография (рентгенограмма) органов грудной клетки
  • РОЛСНС — рекомендации по оценке и лечению при сортировке в неотложных ситуациях
  • РИГА — реакция прямой гемагглютинации
  • р-р — раствор
  • р-ритель — растворитель
  • РРК — рецепторы ретиноевой кислоты
  • РРМ — расширенные реанимационные мероприятия
  • РСВ — респираторно-синцитиальный вирус
  • РСД — расстройство стереотипных движений
  • РСК — реакция связывания комплемента
  • РТГА — реакция торможения гемагглютинации
  • РТНГА — реакция торможения непрямой гемагглютинации
  • РФ — Российская Федерация
  • РХР — ретиноевые Х-рецепторы
  • РЧА — радиочастотная абляция
  • РЭС — ретикулоэндотелиальная система
  • с — секунда
  • св-во — свойство
  • СВДС — синдром внезапной детской смерти
  • СГЯ — синдром гиперстимуляции яичников
  • СД — сахарный диабет
  • СД-1 — сахарный диабет 1 -го типа
  • СД-2 — сахарный диабет 2-го типа
  • СДВГ — синдром дефицита внимания и гиперактивности
  • СЕ — субъединица
  • СЖК — свободные жирные кислоты
  • СЗСТ — системное(ые) заболевание(я) соединительной ткани
  • СИЗ — средства индивидуальной защиты
  • СИОЗС — селективный ингибитор обратного захвата серотонина
  • СИОЗСН — селективные ингибиторы обратного захвата серотонина и норэпинефрина
  • СКА — серповидно-клеточная анемия
  • СКВ — серповидно-клеточная болезнь
  • СКВ — системная красная волчанка
  • СКФ — скорость клубочковой фильтрации
  • СЛР — сердечно-легочная реанимация
  • см — сантиметр
  • см вод.ст. — сантиметр водяного столба
  • СМЖ — спинномозговая жидкость
  • СМИ — средства массовой информации
  • СМО — страховая медицинская организация
  • СМП — скорая медицинская помощь
  • СМЭ — судебно-медицинская экспертиза
  • СН — сердечная недостаточность
  • СНСАДГ — синдром неадекватной секреции АДГ
  • СОАС — синдром обструктивного апноэ сна (во сне)
  • совр. — современный
  • СОЭ — скорость оседания эритроцитов
  • СПИД — синдром приобретенного иммунодефицита
  • СПКЯ — синдром поликистозных яичников
  • СПОН — синдром полиорганной недостаточности
  • СРБ — С-реактивный белок
  • СРК — синдром раздраженного кишечника
  • СрСД — средняя суточная доза
  • ССВ — синдром Стерджа-Вебера
  • ССВР — синдром системной воспалительной реакции
  • ССЗ — сердечно-сосудистые заболевания
  • ССС — сердечно-сосудистая система
  • СССУ — синдром слабости синусового узла
  • СТ — Синдром Туретта
  • СТГ — соматотропный гормон
  • СТР — стойкое (хроническое) моторное или вокальное тикозное расстройство
  • сут — сутки
  • СХУ — синдром хронической усталости
  • т.д. — так далее
  • т.е. — то есть
  • т.к. — так как
  • т.о. — таким образом
  • т.п. — тому подобное
  • Т3 — трийодтиронин
  • Т4 — тироксин
  • ТАНК — тест амплификации нуклеиновых кислот
  • ТБС — тазобедренный сустав
  • ТГВ — тромбоз глубоких вен
  • ТГСК — трансплантация гемопоэтических стволовых клеток
  • ТИА — транзиторная ишемическая атака
  • ТИАБ — тонкоигольная аспирационная биопсия
  • ТМО — твердая мозговая оболочка
  • TH — торговое наименование лекарственных средств
  • ТПГГ — территориальная программа государственных гарантий оказания гражданам РФ бесплатной медицинской помощи
  • ТПМ — травматическое повреждение мозга
  • ТТ — температура тела
  • ТТГ — тиреотропный гормон
  • ТФР — трансформирующий фактор роста
  • ТЦА — трициклические антидепрессанты
  • тыс. — тысяча
  • ТЭД —транзиторная эритробластопения детского возраста
  • ТЭЛА — тромбоэмболия легочной артерии
  • ТЭО — тромбоэмболические осложнения
  • УЗДС — ультразвуковое дуплексное сканирование
  • УЗИ — ультразвуковое исследование
  • устар. — устаревший
  • УФ — ультрафиолетовый
  • УФО — ультрафиолетовое облучение
  • ФАП — фельдшерско-акушерский пункт
  • ФВ — фракция выброса
  • ФВД — функции внешнего дыхания
  • ФЖ — фибрилляция желудочков
  • ФЖЕЛ — форсированная жизненная емкость легких
  • ФЗ — Федеральный закон
  • физиол. — физиологический
  • ФК — функциональный класс
  • ФКС — фиброколоноскопия
  • ФКУ — фенилкетонурия
  • ФН — физическая нагрузка
  • ФНО — фактор некроза опухоли
  • ФОМС — федеральный фонд обязательного медицинского страхования
  • ФОС — фосфорорганические соединения
  • ФП — фибрилляция предсердий
  • фр. — французский
  • ФСГ — фолликулостимулирующий гормон
  • ФСГС — фокально-сегментарный гломерулосклероз
  • ФЭГДС — фиброэзофагогастродуоденоскопия
  • ХБП — хроническая болезнь почек
  • ХГЧ — хорионический гонадотропин человека
  • ХДН — хроническая дыхательная недостаточность
  • хим. — химический
  • ХНЗЛ — хронические неспецифические заболевания легких
  • ХОБЛ — хроническая обструктивная болезнь легких
  • ХПН — хроническая почечная недостаточность
  • ХС — холестерин
  • ХСН — хроническая сердечная недостаточность
  • XT — химиотерапия
  • ЦВД — центральное венозное давление
  • ЦБК — центральный венозный катетер
  • ЦИК — циркулирующие иммунные комплексы
  • ЦМВ — цитомегаловирус
  • ЦНС — центральная нервная система
  • ЦОГ — циклооксигеназа
  • ЦПД — церебральное перфузионное давление
  • ЦСТС — церебральный сольтеряющий синдром
  • ч — час
  • ЧД — частота дыхания
  • ЧДД — частота дыхательных движений
  • ЧКВ — чрескожное коронарное вмешательство
  • ЧМН — черепно-мозговые нервы
  • ЧМТ — черепно-мозговая травма
  • ЧН — черепные нервы
  • ЧС — чувствительность/специфичность (ЧС 97%/87%)
  • ЧСС — частота сердечных сокращений
  • ЧТВ — частичное тромбопластиновое время
  • ШКГ — шкала комы Глазго
  • ШОП — шейный отдел позвоночника
  • ЩЖ — щитовидная железа
  • ЩФ — щелочная фосфатаза
  • ЭАР — эквивалент активности ретинола
  • ЭГДС — эзофагогастродуоденоскопия
  • ЭДТА — этилендиаминтетрауксусная кислота (этилендиаминтетраацетат)
  • ЭКГ — электрокардиография
  • ЭКМО — экстракорпоральная мембранная оксигенация
  • ЭКО — экстракорпоральное оплодотворение
  • ЭКС — электрокардиостимулятор, элекгрокардиостимуляция
  • ЭМГ — электромиография
  • ЭМК — электронная медицинская карта
  • ЭМП — экстренная медицинская помощь
  • ЭНМП — экстренная и неотложная медицинская помощь
  • ЭНМТ — экстремально низкая масса тела
  • ЭРХПГ —эндоскопическая ретроградная холангиопанкреатография
  • ЭТТ — эндотрахеальная трубка
  • ЭхоКГ — эхокардиография
  • ЭЭГ — электроэнцефалография
  • ЮДМ — ювенильный дерматомиозит
  • ЮИА — ювенильный идиопатический артрит
  • ЯБ — язвенная болезнь
  • АА — амилоид A (amyloid А)
  • ААР — Американская академия педиатрии (American Academy of Pediatrics)
  • AASLD — Американская ассоциация по изучению заболеваний печени (American Association for the Study of Liver Diseases)
  • ABC — алгоритм неотложной помощи «дыхательные пути-дыхание-кровообращение» (Airways-Breathing-Circulation)
  • АВСАЗ — белковый член АТФ-связывающей кассеты АЗ
  • АВСВ11 —ген АТФ-связывающей кассеты, 11-й член подсемейства В (ATP-binding cassette, subfamily В member 11)
  • АВСВ4 — ген АТФ-связывающей кассеты, 4-й член подсемейства В (ATP-binding cassette 4 gene)
  • АВСС2 — ген, кодирующий 2-й член подсемейства С АТФ-связывающих кассет (ATP-binding cassette sub-family С member 2)
  • ABCDE — алгоритм неотложной помощи «дыхательные пути-дыхание-кровообращение-не-врологический статус-внешний вид» (Airways-Breathing-Circulation-Disability-Exposure)
  • ABCG5/G8 — гетеродимер переносчика АТФ-связывающей кассеты ABCG5 и ABCG8 (heterodimer of ATP-binding cassette transporter ABCG5 and ABCG8)
  • AC — до еды (при назначениях) — ante cibum
  • АСЕР — Американская коллегия врачей неотложной помощи (American College of Emergency Physicians)
  • ACOG — Американская коллегия акушеров и гинекологов (American College of Obstetricians and Gynecologists)
  • AHA — Американская кардиологическая ассоциация (American Heart Association)
  • ALTE — очевидное опасное для жизни событие (apparent life-threatening event)
  • ANP — предсердный натрийуретический пептид (atrial natriuretic peptide)
  • APLS — курсы расширенных реанимационных мероприятий в педиатрии, спонсируемые Американской академией педиатрии и Американской коллегией врачей неотложной помощи (Advanced Pediatric Life Support)
  • ARPKD — аутосомно-рецессивный поликистоз почек ASCVD-риск — риск развития атеросклеротического сердечно-сосудистого заболевания (Arteriosclerotic Cardiovascular Disease)
  • AVPU — шкала для оценки уровня сознания («в ясном сознании»; «реакция на вербальные раздражители»; «реакция на боль»; «без сознания») (alert, verbal, pain, unresponsive)
  • BCS — митохондриальный шаперон BCS1 (mitochondrial chaperone BCS1)
  • BIN — биноминальная номенклатура живой природы
  • B(i)PAP — режим искусственной вентиляции легких с двумя уровнями положительного давления (bilevel positive airway pressure)
  • BNP — мозговой натрийуретический пептид В-типа [В (brain)-type natriuretic peptide]
  • BRUE — быстро разрешившиеся необъяснимые события (brief resolved unexplained events)
  • BSEP — насос выведения солей желчных кислот (bile salt export pump)
  • CADASIL — церебральная аутосомно-доминантная артериопатия с подкорковыми инфарктами и лейкоэнцефалопатией (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy)
  • CAPS — криопирин-ассоциированный периодический синдром (cryopyrin-associated periodic syndrome)
  • CBIT — комплексное поведенческое воздействие при тиках (comprehensive behavioral intervention for tics)
  • CD — кластеры дифференцировки (clusters of differentiation)
  • CDC — Центр по контролю и профилактике заболеваний, США (Center for Disease Control and Prevention)
  • CDG — врожденные нарушения гликозилирования (congenital disorder of glycosylation)
  • CFTR — трансмембранный регулятор муковисцидоза (cystic fi brosis transmembrane regulator)
  • CH — гемолитический комплемент (hemolytic complement)
  • CLLS — шкала оценки острой горной болезни озера Луиз у детей (Children’s Lake Louise Score)
  • сМОАТ — каналикулярный мультиспецифический органический анионный транспортер (canalicular multispecific organic anion transporter)
  • CMT — Шарко-Мари-Тута болезнь (Charcot-Marie-Tooth disease)
  • CPAP — постоянное положительное давление в дыхательных путях (constant positive airway pressure)
  • CTLA — цитотоксический Т-лимфоцитарный антиген (cytotoxic T-lymphocytic antigen)
  • CYP — цитохром общий
  • DAF — фактор ускорения распада (decay-accelerating factor)
  • DAMP — рецепторы молекулярного фрагмента, ассоциированного с повреждением (damage-associated molecular pattern)
  • DASH — диетические подходы к борьбе с гипертонией (dietary approaches to stop hypertension)
  • DGAT1 — диацилглицерин-1-ацилтрансфераза (diacylglycerol acyltransferase 1)
  • DHR — дигидрородамин (dihydrorhodamine)
  • DSM — Диагностическое и статистическое руководство по психическим расстройствам (Diagnostic and Statistical Manual of Mental Disorders)
  • EAST syndrome — эпилепсия, атаксия, сенсоневральная тугоухость и тубулопатия (epilepsy, ataxia, sensorineural hearing loss, and tubulopath)
  • EBM — доказательная медицина (evidance based medicine)
  • EPCAM — молекула адгезии эпителиальных клеток (epithelial cell adhesion molecule)
  • ESC — Европейское общество кардиологии (European Society of Cardiology)
  • EXIT — лечение плода вне матки во время родов (ех utero intrapartum treatment)
  • FcRs — Fc-рецепторы — белок, расположенный на поверхности нескольких видов клеток иммунной системы (естественных киллеров, макрофагов, нейтрофилов и тучных клеток) FDA — Комитет по контролю за лекарственными веществами и пищевыми добавками, США (Food and Drug Administration)
  • FFR — фракционный резерв кровотока (fractional flow reserve)
  • FGF-23 — фактор роста фибробластов-23 (fibroblast growth factor-23)
  • FIC 1 —семейный внутрипеченочный холестаз 1-го типа, болезнь Байлера (familial intrahepatic cholestasis)
  • FiO2 — фракция кислорода (во вдыхаемом воздухе, газовой смеси)
  • FISH — флуоресцентная in situ гибридизация (fluorescence in situ hybridization)
  • FLAIR — восстановление инверсии с ослаблением жидкости (fluid-attenuated inversion recovery)
  • FMF — семейная средиземноморская лихорадка (familial mediterranean fever)
  • FODMAP — ферментируемые олиго-, ди-, моносахариды и полиолы (fermentable oligo-, di-, monosaccharides and polyols)
  • FoxP3 —транскрипционный фактор семейства Forkhead Р3
  • GATA — gata-связывающий белок
  • DVL — трансплантат против лейкоза (graft versus leukemia)
  • HADH — гидроксилацил-КоА-дегидрогеназа (Hydroxyacyl-Coenzyme A dehydrogenase)
  • HAV — вирус гепатита В (hepatitis A virus)
  • Hb — гемоглобин
  • HBcAg — сердцевинный антиген вируса гепатита В HBeAg — антиген вируса гепатита В
  • HBsAg — поверхностный антиген вируса гепатита В
  • HBV — вирус гепатита В (hepatitis В virus)
  • HCV — вирус гепатита С (hepatitis С virus)
  • HDV — вирус гепатита D (hepatitis D virus)
  • HELLP — HELLP-синдром (гемолиз, повышенный уровень печеночных ферментов, низкий уровень тромбоцитов) (hemolysis, elevated liver enzymes, low platelets)
  • HEV — вирус гепатита E (hepatitis E virus)
  • HFNC — назальные канюли высокого потока (heated, high-flow nasal cannula)
  • Hib — гемофильная палочка типа В (Haemophilus influenzae В type)
  • HLA — лейкоцитарные антигены (главного комплекса гистосовместимости) человека (human leukocyte antigens)
  • HR — отношение рисков (hazard ratio)
  • HRT — терапия отмены привычки (habit reversal therapy)
  • Ht — гематокрит
  • HTLV — Т-лимфотропный вирус человека (human T-lymphotropic virus)
  • IFN — интерферон
  • Ig — иммуноглобулин
  • IgA — иммуноглобулин A
  • IgE — иммуноглобулин E
  • IgG — иммуноглобулин G
  • IgM — иммуноглобулин M
  • IL — интерлейкин
  • IPEX — Х-сцепленный синдром иммунной дисрегуляции, полиэндокринопатии и энтеропатии (immunedysregulation polyendocrinopathy enteropathy, X-linked)
  • IQ — коэффициент умственного развития (intelligence quotient)
  • JAK — янус-киназа (janus kinase)
  • LFA — антиген, активирующий функцию лейкоцитов (lymphocyte function-associated antigen)
  • LT — лейкотриен
  • MALT — лимфоидная ткань слизистой оболочки (mucosa-associated lymphoid tissue)
  • MASP — МСЛ-ассоциированная сериновая протеаза (MBL-associated serine protease)
  • MBL — маннозосвязывающий лектин (mannose-binding lectin)
  • MCP — мембранный белок-кофактор (membrane cofactor protein)
  • MDR3 — белок множественной лекарственной устойчивости 3 (multidrug resistance protein 3)
  • MELAS — митохондриальная энцефалопатия, лактоацидоз и инсультоподобные эпизоды (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes)
  • MELD — модель для оценки терминальной стадии заболеваний печени, предназначена для оценки относительной тяжести заболевания и прогноза жизни у пациентов с терминальной стадией печеночной недостаточности (ожидающих трансплантации печени) (model for end-stage liver disease)
  • MERRF — миоклоническая эпилепсия с рваными красными волокнами (myoclonic epilepsy with ragged red fibers)
  • MHC — главный комплекс гистосовместимости (major histocompatibility complex)
  • Mr — кажущаяся молекулярная масса
  • MRP — белок с множественной лекарственной устойчивостью (multidrug-resistant protein)
  • MRSA — метициллинрезистентный золотистый стафилококк
  • MSSA — метициллинчувствительный золотистый стафилококк
  • mTOR — мишень рапамицина у млекопитающих (mammalian target of rapamycin)
  • NB! — важно, обратить внимание (nota bene)
  • NICE — Национальный институт здоровья и клинического совершенствования (качества медицинской помощи) Великобритании (National Institute for Health and Clinical Excellence)
  • NK — естественные клетки-киллеры (natural killer) NMDA — И-метил-В-аспартат (N-methyl-D-aspartate)
  • NNT — число больных, которых необходимо пролечить, чтобы достичь какого-то указанного эффекта (number need to treatment)
  • OR — отношение шансов (odds ratio)
  • paCO2 — парциальное давление углекислого газа в артериальной крови
  • PALS — курсы расширенных реанимационных мероприятий в педиатрии (Pediatric Advanced Life Support)
  • PANDAS — аутоиммунное нейропсихиатрическое расстройство в детском возрасте, ассоциированное со стрептококковой инфекцией (pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection)
  • PANS — острый нейропсихиатрический синдром в детском возрасте (pediatric acute-onset neuropsychiatric syndrome)
  • paO2 — парциальное давление кислорода в артериальной крови
  • PAS — фуксинсернистая кислота, реактив Шиффа (periodic acid-Shiff)
  • PC — после еды (при назначениях) (post cibum) рСО2 — парциальное давление углекислого газа
  • PCSK-9 — пропротеиновая конвертаза субтилизинкексинового типа 9 (proprotein convertase subtilisin/kexin type 9)
  • PFAPA — периодическая лихорадка с афтозным стоматитом, фарингитом и лимфаденитом (periodic fevers with aphthous stomatitis, pharyngitis and adenitis)
  • PFIC — семейный внутрипеченочный холестаз (familial intrahepatic cholestasis)
  • Pg — простагландин
  • pH — водородный показатель
  • PIM — показатель летального исхода у детей (pediatric index of mortality)
  • piO2 — парциальное давление кислорода во вдыхаемом воздухе
  • рО2 — парциальное давление кислорода
  • POLG — субъединица ДНК-полимеразы γ
  • PRISA II — оценка риска госпитализации у детей II (pediatric risk of admission)
  • PRISM — риск летального исхода у детей (pediatric risk of mortality)
  • PRN — при (по) необходимости (pro re nata — при возникновении обстоятельств)
  • PRSS — ген сериновой протеазы
  • PS — примечание (post scriptum)
  • PUVA-терапия — псорален-ультрафиолет А-терапия (psoralen and ultraviolet А)
  • Q#H — каждые # часов (при назначениях) (quaque... hora)
  • QAM — каждое утро (при назначениях) (quaque ante meridiem)
  • QPM — каждый вечер (при назначениях) (quaque post meridiem)
  • RAG — ген, активирующий рекомбиназу
  • RePEAT — пересмотренный инструмент для оценки педиатрической неотложной медицинской помощи (Revised Pediatric Emergency Assessment Tool)
  • RF — ревматоидный фактор
  • Rh — резус(-фактор)
  • Rh«-» — резус-отрицательн(ый)
  • Rh«+» — резус-положительн(ый)
  • ROHHAD — быстро развивающееся ожирение с дисфункцией гипоталамуса, гиповентиляцией и спонтанной дисрегуляцией (rapid-onset obesity with hypothalamic dysfunction, hypoventilation and autonomic dysregulation)
  • ROMK — почечный наружный мозговой калиевый канал (renal outer medullary К)
  • RR — относительный риск (relative risk или risk ratio)
  • RW — реакция Вассермана (reaction of Wassermann)
  • SaO2 — сатурация артериальной крови кислородом
  • SatO2 — насыщение крови кислородом
  • ScvO2 — насыщение кислородом центральной венозной крови (central venous oxygen saturation)
  • SD — стандартное отклонение (standart deviation)
  • SFTPA — ген сурфактантного белка A
  • SFTPB — ген сурфактантного белка В
  • SFTPC — ген сурфактантного белка С
  • SPINK — ингибитор сериновой протеазы (serine protease inhibitor kazal)
  • SpO2 — насыщение (сатурация) гемоглобина кислородом
  • spp. — виды (при родовом имени микроорганизмов)
  • Src. — источник информации, библиографическая ссылка (source)
  • STAT1 — сигнальный преобразователь и активатор транскрипции 1 (signal transducer and activator of transcription)
  • TA — Международная анатомическая терминология
  • TCR — Т-клеточный рецептор (T-cell receptor)
  • TIPS —трансъюгулярный внутрипеченочный портосистемный шунт; малоинвазивная хирургическая операция, проводимая под контролем рентгеноскопии (transjugular intrahepatic portosystemic shunt)
  • TLR — Толл-подобный рецептор (Toll-like receptor)
  • TNF — фактор некроза опухоли (tumor necrosis factor)
  • TORCH — токсоплазмоз, краснуха, цитомегаловирусная инфекция, герпес и другие инфекции (toxoplasmosis, other infections, rubella, cytomegalovirus herpes simplex)
  • TPM — мутация тропомиозина (mutation of the tropomyosin)
  • TRAP — синдром обратной артериальной перфузии близнецов (twin reversed arterial perfusion)
  • TRAPS — периодический синдром, ассоциированный с рецептором фактора некроза опухоли (tumor necrosis factor receptor-associated periodic syndrome)
  • TRPM — катионный канал с транзиторным рецепторным потенциалом, подсемейство М (transient receptor potential cation channel, subfamily M)
  • VEGF — фактор роста эндотелия сосудов (vascular endothelial growth factor)
  • VO2 — потребление кислорода
  • WPW — синдром Вольфа-Паркинсона-Уайта (Wolff-Parkinson-White)
  • XLA — Х-сцепленная агаммаглобулинемия (X-linked agammaglobulinemia)
  • αDG-RD — дистрофии, связанные с α-дистрогликанами (alpha dystroglycan-related dystrophies)
  • β-ХГЧ — β-субъединица хорионического гонадотропина человека

В ходе подготовки статей по терапии для пользователей сайта МедУнивер использованы труды следующих авторов:

  1. Theofilopoulos AN, Kono DH, Baccala R. The multiple pathways to autoimmunity. Nat Immunol. 2017; 18: 716–724.
  2. Salome B, Jandus C. Innate lymphoid cells in antitumor immunity. J Leukoc Biol. 2018; 103: 479–483.
  3. Bernarreggi D, Pouyanfard S, Kaufman DS. Development of innate immune cells from human pluripotent stem cells. Exp Hematol. 2019; 71: 13–23.
  4. Mortha A, Burrows K. Cytokine networks between innate lymphoid cells and myeloid cells. Front Immunol. 2018; 9: 1–14.
  5. Majer O, Liu B, Barton GM. Nucleic acid-sensing TLRs: trafficking and regulation. Curr Opin Immunol. 2017; 44: 26–33.
  6. Shapouri-Moghaddam A, Mohammadian S, Vazini H, et al. Macrophage plasticity, polarization, and function in health and disease. J Cell Physiol. 2018; 233: 6425–6440.
  7. Li S, Wu J, Zhu S, et al. Disease-associated plasmacytoid dendritic cells. Front Immunol. 2017; 8: 1–12.
  8. Li S, Bostick JW, Zhou L. Regulation of innate lymphoid cells by aryl hydrocarbon receptor. Front Immunol. 2018; 8: 1–13.
  9. Gloude NJ, Khandelwal P, Luebbering N, et al. Circulating dsDNA, endothelial injury, and complement activation in thrombotic microangiopathy and GVHD. Blood. 2017; 130: 1259–1266.
  10. Joosten LA, Abdollahi-Roodsaz S, Dinarello CA, et al. Toll-like receptors and chronic inflammation in rheumatic diseases: new developments. Nat Rev Rheumatol. 2016; 12: 344–357.
  11. Crowl JT, Gray EE, Pestal K, et al. Intracellular nucleic acid detection in autoimmunity. Annu Rev Immunol. 2017; 35: 313–336.
  12. Li T, Chen ZJ. The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer. J Exp Med. 2018; 215: 1287–1299.
  13. Lugrin J, Martinon F. The AIM2 inflammasome: sensor of pathogens and cellular perturbations. Immunol Rev. 2018; 281: 99–114.
  14. PrabhuDas MR, Baldwin CL, Bollyky PL, et al. A consensus definitive classification of scavenger receptors and their roles in health and disease. J Immunol. 2017; 198: 3775–3789.
  15. Pandupuspitasari NS, Khan FA, Huang CJ, et al. Novel attributions of TREMs in immunity. Curr Issues Mol Biol. 2016; 20: 47–54.
  16. Li JT, Zhang Y. TREM2 regulates innate immunity in Alzheimer’s disease. J Neuroinflammation. 2018; 15: 1–7.
  17. Stein MM, Hrusch CL, Gozdz J, et?al. Innate immunity and asthma risk in Amish and Hutterite farm children. N Engl J Med. 2016; 375: 411–421.
  18. Crow MK, Olferiev M, Kirou KA. Targeting of type I interferon in systemic autoimmune diseases. Transl Res. 2015; 165: 296–305.
  19. Lee-Kirsch MA. The type I interferonopathies. Annu Rev Med. 2017; 68: 297–315.
  20. Zak DE, Aderem A. Systems integration of innate and adaptive immunity. Vaccine. 2015; 33: 5241–5248.
  21. Kipnis J. Multifaceted interactions between adaptive immunity and the central nervous system. Science. 2016; 353: 766–771.
  22. Mahe E, Pugh T, Kamel-Reid S. T cell clonality assessment: past, present and future. J Clin Pathol. 2018; 71: 195–200.
  23. Rosenblum MD, Way SS, Abbas AK. Regulatory T cell memory. Nat Rev Immunol. 2016; 16: 90–101.
  24. Khan U, Ghazanfar H. T lymphocytes and autoimmunity. Int Rev Cell Mol Biol. 2018; 341: 125–168.
  25. Dominguez-Villar M, Hafler DA. Regulatory T cells in autoimmune disease. Nat Immunol. 2018; 19: 665–673.
  26. Sigvardsson M. Molecular regulation of differentiation in early B-lymphocyte development. Int J Mol Sci. 2018; 19: 1–15.
  27. Kotas ME, Locksley RM. Why innate lymphoid cells? Immunity. 2018; 48: 1081–1090.
  28. Toben C, Baune BT. An act of balance between adaptive and maladaptive immunity in depression: a role for T lymphocytes. J Neuroimmune Pharmacol. 2015; 10: 595–609.
  29. Rodriguez RM, Suarez-Alvarez B, Lopez-Larrea C. Therapeutic epigenetic reprogramming of trained immunity in myeloid cells. Trends Immunol. 2019; 40: 66–80.
  30. Katsuyama T, Tsokos GC, Moulton VR. Aberrant T cells signaling and subsets in systemic lupus erythematosus. Front Immunol. 2018; 9: 1–15.
  31. Singbartl K, Formeck CL, Kellum JA. Kidney-immune system crosstalk in AKI. Semin Nephrol. 2019; 39: 96–106.
  32. Bournazos S, Ravetch JV. Fc? receptor function and the design of vaccination strategies. Immunity. 2017; 47: 224–233.
  33. White KD, Chung WH, Hung SI, et al. Evolving models of the immunopathogenesis of T cell-mediated drug allergy: the role of host, pathogens, and drug response. J Allergy Clin Immunol. 2015; 136: 219–234.
  34. Siebenhaar F, Redegeld FA, Bischoff SC, et al. Mast cells as drivers of disease and therapeutic targets. Trends Immunol. 2018; 39: 151–162.
  35. Worm M, Francuzik W, Renaudin JM, et al. Factors increasing the risk for a severe reaction in anaphylaxis: an analysis of data from the European Anaphylaxis Registry. Allergy. 2018; 73: 1322–1330.
  36. Ludwig RJ, Vanhoorelbeke K, Leypoldt F, et al. Mechanisms of autoantibody-induced pathology. Front Immunol. 2017; 8: 1–42.
  37. Yorulmaz A, Akin F, Sert A, et al. Demographic and clinical characteristics of patient with serum sickness-like reaction. Clin Rheumatol. 2018; 37: 1389–1394.
  38. Zhang A, Wang K, Zhou C, et al. Knockout of microRNA-155 ameliorates the Th1/Th17 immune response and tissue injury in chronic rejection. J Heart Lung Transplant. 2017; 36: 175–184.
  39. Boyle DL, Soma K, Hodge J, et?al. The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis. Ann Rheum Dis. 2015; 74: 1311–1316.
  40. Firestein GS, McInnes IB. Immunopathogenesis of rheumatoid arthritis. Immunity. 2017; 46: 183–196.
  41. Satoh T, Akira S. Toll-like receptor signaling and its inducible proteins. Microbiol Spectr. 2016; 4: 1–7.
  42. Place DE, Kanneganti TD. Recent advances in inflammasome biology. Curr Opin Immunol. 2017; 50: 32–38.
  43. Al-Ani F, Chin-Yee I, Lazo-Langner A. Eculizumab in the management of paroxysmal nocturnal hemoglobinuria: patient selection and special considerations. Ther Clin Risk Manag. 2016; 12: 1161–1170.
  44. Gupta S, Kaplan MJ. The role of neutrophils and NETosis in autoimmune and renal diseases. Nat Rev Nephrol. 2016; 12: 402–413.
  45. Szekanecz Z, Koch AE. Successes and failures of chemokine-pathway targeting in rheumatoid arthritis. Nat Rev Rheumatol. 2016; 12: 5–13.
  46. Peinhaupt M, Sturm EM, Heinemann A. Prostaglandins and their receptors in eosinophil function and as therapeutic targets. Front Med (Lausanne). 2017; 4: 1–12.
  47. Vitte J. Human mast cell tryptase in biology and medicine. Mol Immunol. 2015; 63: 18–24.
  48. Dutra RC. Kinin receptors: key regulators of autoimmunity. Autoimmun Rev. 2017; 16: 192–207.
  49. Guma M, Tiziani S, Firestein GS. Metabolomics in rheumatic diseases: desperately seeking biomarkers. Nat Rev Rheumatol. 2016; 12: 269–281.
  50. Tost J, Gay S, Firestein G. Epigenetics of the immune system and alterations in inflammation and autoimmunity. Epigenomics. 2017; 9: 371–373.
  51. Keenan CR, Allan RS. Epigenomic drivers of immune dysfunction in aging. Aging Cell. 2018.
  52. Afonina IS, Zhong Z, Karin M, et?al. Limiting inflammation-the negative regulation of NF-kappab and the NLRP3 inflammasome. Nat Immunol. 2017; 18: 861–869.
  53. Derosa G, Sahebkar A, Maffioli P. The role of peroxisome proliferator-activated receptors and their ligands in clinical practice. J Cell Physiol. 2018; 233: 153–161.
  54. Agbowuro AA, Huston WM, Gamble AB, et?al. Proteases and protease inhibitors in infectious diseases. Med Res Rev. 2018; 38: 1295–1331.
  55. Kroger N, Solano C, Wolschke C, et al. Antilymphocyte globulin for prevention of chronic graft-versus-host disease. N Engl J Med. 2016; 374: 43–53.
  56. Vincenti F, Rostaing L, Grinyo J, et al. Belatacept and long-term outcomes in kidney transplantation. Engl J Med. 2016; 374: 333–343.
  57. Migalska M, Sebastian A, Radwan J. Major histocompatibility complex class I diversity limits the repertoire of T cell receptors. Proc Natl Acad Sci USA. 2019; 116: 5021–5026.
  58. DeWolf S, Sykes M. Alloimmune T cells in transplantation. J Clin Invest. 2017; 127: 2473–2481.
  59. Lachmann N, Niemann M, Reinke P, et al. Donor-recipient matching based on predicted indirectly recognizable HLA epitopes independently predicts the incidence of de novo donor-specific HLA antibodies following renal transplantation. Am J Transplant. 2017; 17: 3076–3086.
  60. Kindwall-Keller TL, Ballen KK. Alternative donor graft sources for adults with hematologic malignancies: a donor for all patients in 2017! Oncologist. 2017; 22: 1125–1134.
  61. Morath C, Zeier M, D?hler B, et al. ABO-incompatible kidney transplantation. Front Immunol. 2017; 8: 1–7.
  62. Susal C, Opelz G. Transplantation: desensitization and survival in kidney transplant recipients. Nat Rev Nephrol. 2017; 13: 196–198.
  63. Morin-Zorman S, Loiseau P, Taupin JL, et al. Donor-specific anti-HLA antibodies in allogeneic hematopoietic stem cell transplantation. Front Immunol. 2016; 7: 1–6.
  64. Loupy A, Lefaucheur C. Antibody-mediated rejection of solid-organ allografts. N Engl J Med. 2018; 379: 1150–1160.
  65. Zuber J, Sykes M. Mechanisms of mixed chimerism-based transplant tolerance. Trends Immunol. 2017; 38: 829–843.
  66. Koreth J, Kim HT, Jones KT, et al. Efficacy, durability, and response predictors of low-dose interleu-kin-2 therapy for chronic graft-versus-host disease. Blood. 2016; 128: 130–137.
  67. Thangavelu G, Blazar BR. Achievement of tolerance induction to prevent acute graft-vs.-host disease. Front Immunol. 2019; 10: 1–17.
  68. Munneke JM, Spruit MJ, Cornelissen AS, et al. The potential of mesenchymal stromal cells as treatment for severe steroid-refractory acute graft-versus-host disease: a critical review of the literature. Transplantation. 2016; 100: 2309–2314.
  69. Moy RH, Huffman AP, Richman LP, et al. Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis. Blood. 2017; 129: 906–916.
  70. Lam AJ, Hoeppli RE, Levings MK. Harnessing advances in T regulatory cell biology for cellular therapy in transplantation. Transplantation. 2017; 101: 2277–2287.
  71. Feng S. Spontaneous and induced tolerance for liver transplant recipients. Curr Opin Organ Transplant. 2016; 21: 53–58.
  72. Morris H, DeWolf S, Robins H, et al. Tracking donor-reactive T cells: evidence for clonal deletion in tolerant kidney transplant patients. Sci Transl Med. 2015; 1–12.
  73. Zhang P, Lu Q. Genetic and epigenetic influences on the loss of tolerance in autoimmunity. Cell Mol Immunol. 2018; 15: 575–585.
  74. Barnum S. Complement: a primer for the coming therapeutic revolution. Pharmacol Ther. 2017; 172: 63–72.
  75. Lubbers R., van Essen M.F., van Kooten C., et?al. Production of complement components by cells of the immune system. Clin Exp Immunol. 2017; 188: 183–194.
  76. Hajishengallis G., Reis E.S., Mastellos D.C., et?al. Novel mechanisms and functions of complement. Nat Immunol. 2017; 18: 1288–1298.
  77. Killick J., Morisse G., Sieger D., et?al. Complement as a regulator of adaptive immunity. Semin Immunopathol. 2018; 40: 37–48.
  78. Sandhu V., Quan M. SLE and serum complement: causative, concomitant or coincidental? Open Rheumatol J. 2017; 11: 113–122.
  79. West E.E., Kolev M., Kemper C. Complement and the regulation of T cell responses. Annu Rev Immunol. 2018; 36: 309–338.
  80. Garcia B.L., Zwarthoff S.A., Rooijakkers S.H., et?al. Novel evasion mechanisms of the classical complement pathway. J Immunol. 2016; 197: 2051–2060.
  81. Lopez-Lera A., Corvillo F., Nozal P., et?al. Complement as a diagnostic tool in immunopathology. Semin Cell Dev Biol. 2019; 85: 86–97.
  82. Harrison R.A. The properdin pathway: an «alternative activation pathway» or a «critical amplification loop» for C3 and C5 activation? Semin Immunopathol. 2018; 40: 15–35.
  83. Yaspan B.L., Williams D.F., Holz F.G., et?al. Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration. Science Transl Med. 2017; 9: 1–13.
  84. Angioi A., Fervenza F.C., Sethi S., et?al. Diagnosis of complement alternative pathway disorders. Kidney Int. 2016; 89: 278–288.
  85. Cook H.T., Pickering M.C. Clusters not classifications: making sense of complement-mediated kidney injury. J Am Soc Nephrol. 2018; 29: 9–12.
  86. Jokiranta T.S. HUS and atypical HUS. Blood. 2017; 129: 2847–2856.
  87. Skattum L. Analysis of C3 nephritic factors by ELISA. Methods Mol Biol. 2019; 1901: 177–182.
  88. Toomey C.B., Johnson L.V., Bowes Rickman C. Complement factor H in AMD: bridging genetic associations and pathobiology. Prog Retin Eye Res. 2018; 62: 38–57.
  89. Wong E.K.S., Kavanagh D. Diseases of complement dysregulation — an overview. Semin Immunopathol. 2018; 40: 49–64.
  90. Stark Z., Dolman L., Manolio T.A., et?al. Integrating genomics into healthcare: a global responsibility. Am J Hum Genet. 2019; 104: 13–20.
  91. Waye M.M.Y., Cheng H.Y. Genetics and epigenetics of autism: a review. Psychiatry Clin Neurosci. 2018; 72: 228–244.
  92. Green R.C., Goddard K.A., Jarvik G.P., et?al. Clinical sequencing exploratory research consortium: accelerating evidence-based practice of genomic medicine. Am J Hum Genet. 2016; 98: 1051–1066.
  93. Lantos J.D. Ethical and psychosocial issues in whole genome sequencing (WGS) for newborns. Pediatrics. 2019; 143: S1–S5.
  94. Ganna A., Satterstrom F.K., Zekavat S.M., et?al. Quantifying the impact of rare and ultra-rare coding variation across the phenotypic spectrum. Am J Hum Genet. 2018; 102: 1204–1211.
  95. Hui L., Bianchi D.W. Noninvasive prenatal DNA testing: the vanguard of genomic medicine. Annu Rev Med. 2017; 68: 459–472.
  96. Yang L., Chen J., Shen B. Newborn screening in the era of precision medicine. Adv Exp Med Biol. 2017; 1005: 47–61.
  97. Board PDQCGE. Cancer genetics risk assessment and counseling (PDQ®): health professional version. PDQ cancer information summaries. Bethesda (MD): National Cancer Institute (US); 2018.
  98. Callier S.L., Abudu R., Mehlman M.J., et?al. Ethical, legal, and social implications of personalized genomic medicine research: current literature and suggestions for the future. Bioethics. 2016; 30: 698–705.
  99. Kalia S.S., Adelman K, Bale SJ, et?al. Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American college of medical genetics and genomics. Genet Med. 2017; 19: 249–255.
  100. Nolte I.M., van der Most P.J., Alizadeh B.Z., et?al. Missing heritability: is the gap closing? An analysis of 32 complex traits in the lifelines cohort study. Eur J Hum Genet. 2017; 25: 877–885.
  101. Khera A.V., Chaffin M., Aragam K.G., et?al. Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. Nat Genet. 2018; 50: 1219–1224.
  102. Collins F.S., Varmus H. A new initiative on precision medicine. N Engl J Med. 2015; 372: 793–795.
  103. Schram A.M., Berger M.F., Hyman D.M. Precision oncology: charting a path forward to broader deploy-ment of genomic profiling. PLoS Med. 2017; 14: 1–14.
  104. Zhang G., Nebert D.W. Personalized medicine: genetic risk prediction of drug response. Pharmacol Ther. 2017; 175: 75–90.
  105. Shendure J, Findlay GM, Snyder MW. Genomic medicine-progress, pitfalls, and promise. Cell. 2019; 177: 45–57.
  106. Prohaska A, Racimo F, Schork AJ, et al. Human disease variation in the light of population genomics. Cell. 2019; 177: 115–131.
  107. Chalravorty S, Hegde M. Gene and variant annotation for Mendelian disorders in the era of advanced sequencing technologies. Annu Rev Genomics Hum Genet. 2017; 31: 229–256.
  108. Mackay DJG, Temple IK. Human imprinting disorders: principles, practice, problems and progress. Eur J Med Genet. 2017; 60: 618–626.
  109. Deltas C. Digenic inheritance and genetic modifiers. Clin Genet. 2018; 93: 429–438.
  110. Forsberg LA, Gisselsson D, Dumanski JP. Mosaicism in health and disease — clones picking up speed. Nat Rev Genet. 2017; 18: 128–142.
  111. Kaufman BA, Picard M, Sondheimer N. Mitochondrial DNA, nuclear context, and the risk for carcinogenesis. Environ Mol Mutagen. 2019; 60: 455–462.
  112. Hannan AJ. Tandem repeats mediating genetic plasticity in health and disease. Nat Rev Genet. 2018; 19: 286–298.
  113. Takumi T, Tamada K. CNV biology in neurodevelopmental disorders. Curr Opin Neurobiol. 2018; 48: 183–192.
  114. Nowakowska B. Clinical interpretation of copy number variants in the human genome. J Appl Genet. 2017; 58: 449–457.
  115. Yoshimoto M, Ludkovski O, Good J, et al. Use of multicolor fluorescence in situ hybridization to detect deletions in clinical tissue sections. Lab Invest. 2018; 98: 403–413.
  116. Richards S, Aziz N, Bale S, et al. Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. Genet Med. 2015;17:405-424.
  117. Ginsburg GS, Willard H. Genomic and Personalized Medicine. 3rd ed. Philadelphia: Academic Press; 2016.
  118. Miller NA, Farrow EG, Gibson M, et al. A 26-hour system of highly sensitive whole genome sequenc-ing for emergency management of genetic diseases. Genome Med. 2015; 7: 1–16.
  119. Foss DV, Hochstrasser ML, Wilson RC. Clinical applications of CRISPR-based genome editing and diagnostics. Transfusion. 2019; 59: 1389–1399.
  120. Biesecker LG, Nussbaum RL, Rehm HL. Distinguishing variant pathogenicity from genetic diagnosis: how to know whether a variant causes a condition. JAMA. 2018; 320: 1929–1930.
  121. Farnaes L, Hildreth A, Sweeney NM, et al. Rapid whole-genome sequencing decreases infant mor-bidity and cost of hospitalization. NPJ Genom Med. 2018; 3: 1–8.
  122. Splinter K, Adams DR, Bacino CA, et al. Effect of genetic diagnosis on patients with previously undiagnosed disease. N Engl J Med. 2018; 379: 2131–2139.
  123. Dey N, Williams C, Leyland-Jones B, et al. Mutation matters in precision medicine: a future to believe in. Cancer Trust Rev. 2017; 55: 136–149.
  124. Kan B, Zhou H, Du P, et al. Transforming bacterial disease surveillance and investigation using whole-genome sequence to probe the trace. Front Med. 2018; 12: 23–33.
  125. Hoffman JM, Lyu Y, Pletcher SD, et al. Proteomics and metabolomics in ageing research: from biomarkers to systems biology. Essays Biochem. 2017; 61: 379–388.
  126. Li H, Han J, Pan J, et al. Current trends in quantitative proteomics — an update. J Mass Spectrom. 2017; 52: 319–341.
  127. Adams DR, Eng CM. Next-generation sequencing to diagnose suspected genetic disorders. N Engl J Med. 2018; 379: 1353–1362.
  128. Castanada C, Nalley K, Mannion C, et al. Clinical decision support systems for improving diagnostic accuracy and achieving precision medicine. J Clin Bioinforma. 2015; 5: 1–16.
  129. Aronson S, Rehm N. Building the foundation for genomics in precision medicine. Nature. 2015; 526: 336–342.
  130. Ratcliff CL, Kaphingst KA, Jensen JD. When personal feels invasive: foreseeing challenges in preci-sion medicine communication. J Health Commun. 2018; 23: 144–152.
  131. U.S. Equal Employment Opportunity Commission. The genetic information nondiscrimination act of 2008. https://www.eeoc.gov/laws/statutes/gina.cfm. Accessed June 5, 2019.
  132. Ginsburg GS, Finkelman E, Balatbat C, et al. Precision medicine: a global action plan for impact. Doha, Qatar: World Innovation Summit for Health; 2016. http://www.wish.org.qa/wp-content/ uploads/2018/01/IMPJ4495_WISH_Precision_Medicine_Report_WEB.pdf. Accessed June 5, 2019.
  133. Wen Y, Ding J, Zhang B, et al. Bone marrow-derived mononuclear cell therapy for non-ischemic dilated cardiomyopathy: a meta-analysis. Eur J Clin Invest. 2018; 48: 1–9.
  134. Jeyaraman MM, Rabbani R, Copstein L, et al. Autologous bone marrow stem cell therapy in patients with ST-elevation myocardial infarction: a systematic review and meta-analysis. Can J Cardiol. 2017; 33: 1611–1623.
  135. Greenberg B, Butler J, Felker GM, et al. Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial. Lancet. 2016; 387: 1178–1186.
  136. Adams D, Gonzalez-Duarte A, O’Riordan WD, et al. Patisiran, an RNAi therapeutic, for hereditary transthyretin amyloidosis. N Engl J Med. 2018; 379: 11–21.
  137. Ray KK, Landmesser U, Leiter LA, et al. Inclisiran in patients at high cardiovascular risk with elevated LDL cholesterol. N Engl J Med. 2017; 376: 1430–1440.
  138. Higuchi A, Kumar SS, Benelli G, et al. Stem cell therapies for reversing vision loss. Trends Biotechnol. 2017; 35: 1102–1117.
  139. Khademhosseini A, Langer R. A decade of progress in tissue engineering. Nat Protoc. 2016; 11: 1775–1781.
  140. Kikuchi T, Morizane A, Doi D, et al. Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model. Nature. 2017; 548: 592–596.
  141. Eschenhagen T, Bolli R, Braun T, et al. Cardiomyocyte regeneration: a consensus statement. Circula-tion. 2017; 136: 680–686.
  142. Melton DA. Applied developmental biology: making human pancreatic beta cells for diabetics. Curr Top Dev Biol. 2016; 117: 65–73.
  143. Dunbar CE, High KA, Joung JK, et al. Gene therapy comes of age. Science. 2018; 359: 1–10.
  144. Cicalese MP, Ferrua F, Castagnaro L, et al. Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency. Blood. 2016; 128: 45–54.
  145. Bainbridge JW, Mehat MS, Sundaram V, et al. Long-term effect of gene therapy on Leber’s congenital amaurosis. N Engl J Med. 2015; 372: 1887–1897.
  146. George LA, Sullivan SK, Giermasz A, et al. Hemophilia B gene therapy with a high-specific-activity Factor IX variant. N Engl J Med. 2017; 377: 2215–2227.
  147. Samelson-Jones BJ, Arruda VR. Protein-engineered coagulation factors for hemophilia gene therapy. Mol Ther Methods Clin Dev. 2019; 12: 184–201.
  148. Penny WF, Hammond HK. Randomized clinical trials of gene transfer for heart failure with reduced ejection fraction. Hum Gene Ther. 2017; 28: 378–384.
  149. June CH, Sadelain M. Chimeric antigen receptor therapy. N Engl J Med. 2018; 379: 64–73.
  150. Chakraborty C, Sharma AR, Sharma G, et al. Therapeutic miRNA and siRNA: moving from bench to clinic as next generation medicine. Mol Ther Nucleic Acids. 2017; 8: 132–143.
  151. Skipper KA, Mikkelsen JG. Toward in vivo gene therapy using CRISPR. Methods Mol Biol. 2019; 1961: 293–306.
  152. Cornu TI, Mussolino C, Cathomen T. Refining strategies to translate genome editing to the clinic. Nat Med. 2017; 23: 415–423.
  153. Hill-Taylor B., Walsh K.A., Stewart S., et al. Effectiveness of the STOPP/START (screening tool of older persons’ potentially inappropriate prescriptions/screening tool to alert doctors to the right treatment) criteria: systematic review and meta-analysis of randomized controlled studies. J Clin Pharm Ther. 2016; 41: 158–169.
  154. O’Connor M.N., O’Sullivan D., Gallagher P.F., et al. Prevention of hospital-acquired adverse drug reactions in older people using screening tool of older persons’ prescriptions and screening tool to alert to right treatment criteria: a cluster randomized controlled trial. J Am Geriatr Soc. 2016; 64: 1558–1566.
  155. Zheng W.Y., Richardson L.C., Li L., et al. Drug-drug interactions and their harmful effects in hospitalised patients: a systematic review and meta-analysis. Eur J Clin Pharmacol. 2018; 74: 15–27.
  156. Shehab N., Lovegrove M.C., Geller A.I., et al. US emergency department visits for outpatient adverse drug events, 2013-2014. JAMA. 2016; 316: 2115–2125.
  157. Geller A.I., Lovegrove M.C., Shehab N., et al. National estimates of emergency department visits for antibiotic adverse events among adults — United States, 2011–2015. J Gen Intern Med. 2018; 33: 1060–1068.
  158. Lee J., Noh Y., Lee S. Evaluation of preventable adverse drug reactions by implementation of the nationwide network of prospective drug utilization review program in Korea. PLoS ONE. 2018; 13: 1–10.
  159. Plumpton C.O., Roberts D., Pirmohamed M., et al. A systematic review of economic evaluations of pharmacogenetic testing for prevention of adverse drug reactions. Pharmacoeconomics. 2016; 34: 771–793.
  160. Mizzi C., Dalabira E., Kumuthini J., et al. A European spectrum of pharmacogenomic biomarkers: implications for clinical pharmacogenomics. PLoS ONE. 2016; 11: 1–19.
  161. Larkin J., Brown M.P., Arance A.M., et al. An open-label, multicentre safety study of vemurafenib in patients with BRAF(V600)-mutant metastatic melanoma: final analysis and a validated prognostic scoring system. Eur J Cancer. 2019; 107: 175–185.
  162. Cohen SP, Gupta A, Strassels SA, et al. Does MRI affect outcomes in patients with lumbosacral radiculopathy referred for epidural steroid injections? A randomized, double-blind, controlled study. Arch Intern Med. 2012; 172: 134–142.
  163. Zunhammer M, Bingel U, Wager TD. Placebo effects on the neurologic pain signature: a metaanalysis of individual participant functional magnetic resonance imaging data. JAMA Neurol.2018; 75: 1321–1330.
  164. Derry S, Conaghan P, Da Silva JA, et al. Topical NSAIDs for chronic musculoskeletal pain in adults. Cochrane Database Syst Rev. 2016; 4: CD007400.
  165. Mathieson S, Maher CG, McLachlan AJ, et al. Trial of pregabalin for acute and chronic sciatica. N Engl J Med. 2017; 376: 1111–1120.
  166. Moore RA, Wiffen PJ, Derry S, et al. Gabapentin for chronic neuropathic pain and fibromyalgia in adults. Cochrane Database Syst Rev. 2014; 4: CD007938.
  167. Clarke H, Bonin RP, Orser BA, et al. The prevention of chronic postsurgical pain using gabapentin and pregabalin: a combined systematic review and meta-analysis. Anesth Analg. 2012; 115: 428–442.
  168. Derry S, Rice AS, Cole P, et al. Topical capsaicin (high concentration) for chronic neuropathic pain in adults. Cochrane Database Syst Rev. 2017; 1: CD007393.
  169. Whiting PF, Wolff RF, Deshpande S, et al. Cannabinoids for medical use: a systematic review and meta-analysis. JAMA. 2015; 313: 2456–2473.
  170. Hegmann KT, Weiss MS, Bowden K, et al. American College of Occupational and Environmental Medicine. ACOEM practice guidelines: opioids for treatment of acute, subacute, chronic, and postoperative pain. J Occup Environ Med. 2014; 56: e143–e159.
  171. Chang AK, Bijur PE, Esses D, et al. Effect of a single dose of opioid and nonopioid analgesics on acute extremity pain in the emergency department: a randomized clinical trial. JAMA. 2017; 318: 1661–1667.
  172. Dowell D, Haegerich TM, Chou R. CDC guideline for prescribing opioids for chronic pain—United States, 2016. JAMA. 2016; 315: 1624–1645.
  173. Gilron I, Tu D, Holden RR, et al. Combination of morphine with nortriptyline for neuropathic pain. Pain. 2015; 156: 1440–1448.
  174. Shanthanna H, Gilron I, Rajarathinam M, et al. Benefits and safety of gabapentinoids in chronic low back pain: a systematic review and meta-analysis of randomized controlled trials. PLoS Med. 2017; 14: 1–21.
  175. Steenstra IA, Munhall C, Irvin E, et al. Systematic review of prognostic factors for return to work in workers with sub acute and chronic low back pain. J Occup Rehabil. 2017; 27: 369–381.
  176. Cherkin DC, Anderson ML, Sherman KJ, et al. Two-year follow-up of a randomized clinical trial of mindfulness-based stress reduction vs cognitive behavioral therapy or usual care for chronic low back pain. JAMA. 2017; 317: 642–643.
  177. Meheux CJ, McCulloch PC, Lintner DM, et al. Efficacy of intra-articular platelet-rich plasma injections in knee osteoarthritis: a systematic review. Arthroscopy. 2016; 32: 495–505.
  178. Tsikopoulos K, Tsikopoulos I, Simeonidis E, et al. The clinical impact of platelet-rich plasma on tendinopathy compared to placebo or dry needling injections: a meta-analysis. Phys Ther Sport. 2016; 17: 87–94.
  179. Juch JNS, Maas ET, Ostelo RWJG, et al. Effect of radiofrequency denervation on pain intensity among patients with chronic low back pain: the mint randomized clinical trials. JAMA. 2017; 318: 68–81.
  180. Jacobs WC, van Tulder M, Arts M, et al. Surgery versus conservative management of sciatica due to a lumbar herniated disc: a systematic review. Eur Spine J. 2011; 20: 513–522.
  181. Kovacs FM, Urr?tia G, Alarc?n JD. Surgery versus conservative treatment for symptomatic lumbar spinal stenosis: a systematic review of randomized controlled trials. Spine. 2011; 36: E1335–E1351.
  182. Jacobs W, Van der Gaag NA, Tuschel A, et al. Total disc replacement for chronic back pain in the presence of disc degeneration. Cochrane Database Syst Rev. 2012; (9): CD008326.
  183. Hedlund R, Johansson C, H?gg O, et al. Swedish lumbar spine study group. The long-term outcome of lumbar fusion in the Swedish lumbar spine study. Spine J. 2016; 16: 579–587.
  184. Nahin RL. Estimates of pain prevalence and severity in adults: United States, 2012. J Pain. 2015; 16: 769–780.
  185. Treede RD, Rief W, Barke A, et al. Chronic pain as a symptom or a disease: the IASP classification of chronic pain for the international classification of diseases (ICD-11). Pain. 2019; 160: 19–27.
  186. Wenger HC, Cifu AS. Treatment of low back pain: JAMA clinical guidelines synopsis. JAMA. 2017; 318: 743–744.
  187. Crofford LJ. Chronic pain: where the body meets the brain. Trans Am Clin Climatol Assoc. 2015; 126: 167–183.
  188. Colloca L, Ludman T, Bouhassira D, et al. Neuropathic pain. Nat Rev Dis Primers. 2017; 3: 1–19.
  189. Bjorland S, Moen A, Schistad E, et al. Genes associated with persistent lumbar radicular pain; a systematic review. BMC Musculoskelet Disord. 2016; 17: 1–10.
  190. Davis KD, Flor H, Greely HT, et al. Brain imaging tests for chronic pain: medical, legal and ethical issues and recommendations. Nat Rev Neurol. 2017; 13: 624–638.
  191. Sivertsen B, Lallukka T, Petrie KJ, et al. Sleep and pain sensitivity in adults. Pain. 2015; 156: 1433–1439.
  192. Finnerup NB, Attal N, Haroutounian S, et al. Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Lancet Neurol. 2015; 14: 162–173.
  193. Mathieson S, Kasch R, Maher CG, et al. Combination drug therapy for the management of low back pain and sciatica: systematic review and meta-analysis. J Pain. 2019; 20: 1–15.
  194. Ghoneim MM, O’Hara MW. Depression and postoperative complications: an overview. BMC Surg. 2016; 16: 1–10.
  195. Marcia S, Zini C, Hirsch JA, et al. Steroids spinal injections. Semin Intervent Radiol. 2018; 35: 290–298.
  196. Ju ZY, Wang K, Cui HS, et al. Acupuncture for neuropathic pain in adults. Cochrane Database Syst Rev. 2017; 12: CD012057.
  197. Paige NM, Miake-Lye IM, Booth MS, et al. Association of spinal manipulative therapy with clinical benefit and harm for acute low back pain: systematic review and meta-analysis. JAMA. 2017; 317: 1451–1460.
  198. Dentino A, Medina R, Steinberg E. Pain in the elderly: identification, evaluation, and management of older adults with pain complaints and pain-related symptoms. Prim Care. 2017; 44: 519–528.
  199. Ehlers C.L., Gilder D.A., Gizer I.R., et al. Indexing the «dark side of addiction»: substance-induced affective symptoms and alcohol use disorders. Addiction. 2019; 114: 139–149.
  200. Bohler K.M., Gin? E., Echeverry-Alzate V., et al. Common single nucleotide variants underlying drug addiction: more than a decade of research. Addict Biol. 2015; 20: 845–871.
  201. Reilly M.T., Noronha A., Goldman D., et al. Genetic studies of alcohol dependence in the context of the addiction cycle. Neuropharmacology. 2017; 122: 3–21.
  202. Vink J.M. Genetics of addiction: future focus on gene x environment interaction? J Stud Alcohol Drugs. 2016; 77: 684–687.
  203. Egervari G., Ciccocioppo R., Jentsch J.D., et al. Shaping vulnerability to addiction — the contribution of behavior, neural circuits and molecular mechanisms. Neurosci Biobehav Rev. 2018; 85: 117–125.
  204. Banz B.C., Yip S.W., Yau Y.H., et al. Behavioral addictions in addiction medicine: from mechanisms to practical consideration. Prog Brain Res. 2016; 223: 311–328.
  205. Lewis M. Brain change in addiction as learning, not disease. N Engl J Med. 2018; 379: 1551–1560.
  206. Ajonijebu D.C., Abboussi D., Russell V.A., et al. Epigenetics: a link between addiction and social environment. Cell Mol Life Sci. 2017; 74: 2735–2747.
  207. Koob G.F., Volkow N.D. Neurobiology of addiction: a neurocircuitry analysis. Lancet Psychiatry. 2016; 3: 760–773.
  208. Rose J.E., Behm F.M. Adapting smoking cessation treatment according to initial response to preces- sation nicotine patch. Am J Psychiatry. 2013; 170: 860–867.
  209. Hartmann-Boyce J., Chepkin S.C., Ye W., et al. Nicotine replacement therapy versus control for smoking cessation. Cochrane Database Syst Rev. 2018; 5: CD000146.
  210. Patnode C.D., Henderson J.T., Thompson J.H., et al. Behavioral counseling and pharmacotherapy interventions for tobacco cessation in adults, including pregnant women: a review of reviews for the U.S. Preventive Services Task Force. Ann Intern Med. 2015; 163: 608–621.
  211. Sterling L.H., Windle S.B., Filion K.B., etal. Varenicline and adverse cardiovascular events: a systematic review and meta-analysis of randomized controlled trials. J Am Heart Assoc. 2016; 1–11.
  212. Benowitz N.L., Pipe A., West R., et al. Cardiovascular safety of varenicline, bupropion, and nicotine patch in smokers: a randomized clinical trial. JAMA Intern Med. 2018; 178: 622–631.
  213. Anthenelli R., Benowitz N.L., West R., et al. Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial. Lancet. 2016; 387: 2507–2520.
  214. Rose J.E., Behm F.M. Adaptive smoking cessation to initial response to precessation nicotine patch. Am J Psychiatry. 2013; 170: 860–867.
  215. Cinciripini P.M., Minnix J.A., Green C.E., et al. An RCT with the combination of varenicline and bupropion for smoking cessation: clinical implications for front line use. Addiction. 2018; 113: 1673–1682.
  216. Halpern S.D., Harhay M.O., Saulsgiver K., et al. A pragmatic trial of e-cigarettes, incentives,and drugs for smoking cessation. N Engl J Med. 2018; 378: 2302–2310.
  217. Masiero M., Lucchiari C., Mazzocco K., et al. E-cigarettes may support smokers with high smoking- related risk awareness to stop smoking in the short run: preliminary results by randomized controlled trial. Nicotine Tob Res. 2019; 21: 119–126.
  218. Wang T.W., Asman K., Gentzke A.S., et al. Tobacco product use among adults — United States, 2017. MMWR Morb Mortal Wkly Rep. 2018; 67: 1225–1232.
  219. GBD 2015 Tobacco Collaborators. Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: a systematic analysis from the Global Burden of Disease Study 2015. Lancet. 2017; 389: 1885–1906.
  220. D’Souza M.S. Neuroscience of nicotine for addiction medicine: novel targets for smoking cessation medications. Prog Brain Res. 2016; 223: 191–214.
  221. Barua R.S., Rigotti N.A., Benowitz N.L., et al. 2018 ACC expert consensus decision pathway on tobacco cessation treatment: a report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol. 2018; 72: 3332–3365.
  222. Gamez-Coronado N., Walker A.J., Berk M., et al. Current and emerging pharmacotherapies for cessation of tobacco smoking. Pharmacotherapy. 2018; 38: 235–258.
  223. Vogeler T., McClain C., Evoy K.E. Combination bupropion SR and varenicline for smoking cessation: a systematic review. Am J Drug Alcohol Abuse. 2016; 42: 129–139.
  224. Franks A.S., Sando K., McBane S. Do electronic cigarettes have a role in tobacco cessation? Pharmacotherapy. 2018; 38: 555–566.
  225. Hartmann-Boyce J., Begh R., Aveyard P. Electronic cigarettes for smoking cessation. BMJ. 2018; 360: 1–8.
  226. Dinakar C., O’Connor G.T. The health effects of electronic cigarettes. N Engl J Med. 2016; 375: 1372–1381.
  227. Livingston C.J., Freeman R.J., Costales V.C., et al. Electronic nicotine delivery systems or e-cigarettes: American College of Preventive Medicine’s practice statement. Am J Prev Med. 2019; 56: 167–178.
  228. Joseph J, Basu D. Efficacy of brief interventions in reducing hazardous or harmful alcohol use in middle-income countries: systematic review of randomized controlled trials. Alcohol Alcohol. 2017; 52: 56–64.
  229. Jonas DE, Amick HR, Feltner C, et al. Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis. JAMA. 2014; 311: 1889–1900.
  230. Oslin DW, Leong SH, Lynch KG, et al. Naltrexone vs placebo for the treatment of alcohol dependence: a randomized clinical trial. JAMA Psychiatry. 2015; 72: 430–437.
  231. Mason BJ, Quello S, Goodell V, et al. Gabapentin treatment for alcohol dependence: a randomized clinical trial. JAMA Intern Med. 2014; 174: 70–77.
  232. GBD 2016 Alcohol Collaborators. Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2018; 392: 1015–1035.
  233. Substance Abuse and Mental Health Services Administration. Results from the 2013 National Survey on Drug Use and Health: overview of findings. https://www.samhsa.gov/data/sites/default/files/NSDUHresultsPDFWHTML2013/Web/NSDUHresults2013.pdf. Accessed June 4, 2019.
  234. Donroe JH, Tetrault JM. Recognizing and caring for the intoxicated patient in an outpatient clinic. Med Clin North Am. 2017; 101: 573–586.
  235. Maldonado JR. Novel algorithms for the prophylaxis and management of alcohol withdrawal syndromes—beyond benzodiazepines. Crit Care Clin. 2017; 33: 559–599.
  236. Whitman IR, Agarwal V, Nah G, et al. Alcohol abuse and cardiac disease. J Am Coll Cardiol. 2017; 69: 13–24.
  237. Kourkoumpetis T, Sood G. Pathogenesis of alcoholic liver disease: an update. Clin Liver Dis. 2019; 23: 71–80.
  238. Ratna A, Mandrekar P. Alcohol and cancer: mechanisms and therapies. Biomolecules. 2017; 7: 1–20.
  239. Curry SJ, Krist AH, Owens DK, et al. Screening and behavioral counseling interventions to reduce unhealthy alcohol use in adolescents and adults: US Preventive Services Task Force recommendation statement. JAMA. 2018; 320: 1899–1909.
  240. Connor JP, Haber PS, Hall WD. Alcohol use disorders. Lancet. 2016; 387: 988–998.
  241. Edelman EJ, Fiellin DA. In the clinic. Alcohol use. Ann Intern Med. 2016; 164: ITC1-16.
  242. Jonas DE, Garbutt JC. Screening and counseling for unhealthy alcohol use in primary care setting. Med Clin North Am. 2017; 101: 823–837.
  243. Wood E, Albarqouni L, Tkachuk S, et al. Will this hospitalized patient develop severe alcohol withdrawal syndrome? The rational clinical examination systematic review. JAMA. 2018; 320: 825–833.
  244. Jesse S, Brathen G, Ferrara M, et al. Alcohol withdrawal syndrome: mechanisms, manifestations, and management. Acta Neurol Scand. 2017; 135: 4–16.
  245. Soyka M, M?ller CA. Pharmacotherapy of alcoholism — an update on approved and off-label medications. Expert Opin Pharmacother. 2017; 18: 1187–1199.
  246. Kranzler HR, Soyka M. Diagnosis and pharmacotherapy of alcohol use disorder: a review. JAMA. 2018; 320: 815–824.
  247. Gowing L, Ali R, White JM, et al. Buprenorphine for managing opioid withdrawal. Cochrane Database Syst Rev. 2017; 2: CD002025.
  248. Dunn KE, Tompkins DA, Bigelow GE, et al. Efficacy of tramadol extended-release for opioid withdrawal: a randomized clinical trial. JAMA Psychiatry. 2017; 74: 885–893.
  249. Nielsen S, Larance B, Degenhardt L, et al. Opioid agonist treatment for pharmaceutical opioid dependent people. Cochrane Database Syst Rev. 2016; 5: CD011117.
  250. Minozzi S, Amato L, Bellisario C, et al. Maintenance treatments for opiate-dependent adolescents. Cochrane Database Syst Rev. 2014; 6: CD007210.
  251. D’Onofrio G, O’Connor PG, Pantalon MV, et al. Emergency department-initiated buprenorphine/naloxone treatment for opioid dependence: a randomized clinical trial. JAMA. 2015; 313: 1636–1644.
  252. Mattick RP, Breen C, Kimber J, et al. Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence. Cochrane Database Syst Rev. 2014; 2: CD002207.
  253. Weiss RD, Potter JS, Fiellin DA, et al. Adjunctive counseling during brief and extended buprenorphinenaloxone treatment for prescription opioid dependence a 2-phase randomized controlled trial. Arch Gen Psychiatry. 2011; 68: 1238–1246.
  254. Sigmon SC, Dunn KE, Saulsgiver K, et al. A randomized, double-blind evaluation of buprenorphine taper duration in primary prescription opioid abusers. JAMA Psychiatry. 2013; 70: 1347–1354.
  255. Lee JD, Friedmann PD, Kinlock TW, et al. Extended-release naltrexone to prevent opioid relapse in criminal justice offenders. N Engl J Med. 2016; 374: 1232–1242.
  256. Seth P, Scholl L, Rudd RA, et al. Overdose deaths involving opioids, cocaine, and psychostimulants—United States, 2015-2016. MMWR Morb Mortal Wkly Rep. 2018; 67: 349–358.
  257. Egervari G, Ciccocioppo R, Jentsch JD, et al. Shaping vulnerability to addiction—the contribution of behavior, neural circuits and molecular mechanisms. Neurosci Biobehav Rev. 2018; 85: 117–125.
  258. Brosrus J, Gentile N, Esseiva P. The cutting of cocaine and heroin: a critical review. Forensic Sci Int. 2016; 262: 73–83.
  259. Frank RG, Pollack HA. Addressing the fentanyl threat to public health. N Engl J Med. 2017; 376: 605–607.
  260. Gomes T, Tadrous M, Mamdani MM, et al. The burden of opioid-related mortality in the United States. JAMA Netw Open. 2018; 1: 1–6.
  261. Dart RC, Surratt HL, Cicero TJ, et al. Trends in opioid analgesic abuse and mortality in the United States. N Engl J Med. 2015; 372: 241–248.
  262. Chou R, Korthuis PT, McCarty D, et al. Management of suspected opioid overdose with naloxone in out-of-hospital settings: a systematic review. Ann Intern Med. 2017; 167: 867–875.
  263. Sun EC, Dixit A, Humphreys K, et al. Association between concurrent use of prescription opioids and benzodiazepines and overdose: retrospective analysis. BMJ. 2017; 356: 1–7.
  264. Schuckit MA. Treatment of opioid-use disorders. N Engl J Med. 2016; 375: 357–368.
  265. Cisewski DH, Santos C, Koyfman A, et al. Approach to buprenorphine use for opioid withdrawal treatment in the emergency setting. Am J Emerg Med. 2019; 37: 143–150.
  266. Carroll KM, Weiss RD. The role of behavioral interventions in buprenorphine mainenance treatment: a review. Am J Psychiatry. 2017; 174: 738–747.
  267. Prakash MD, Tangalakis K, Antonipillai J, et al. Methamphetamine: effects on the brain, gut and immune system. Pharmacol Res. 2017; 120: 60–67.
  268. Ebbert JO, Scharf EL, Hurt RT. Medical cannabis. Mayo Clin Proc. 2018; 93: 1842–1847.
  269. Baggish AL, Weiner RB, Kanayama G, et al. Cardiovascular toxicity of illicit anabolic-androgenic steroid use. Circulation. 2017; 135: 1991–2002.
  270. Desmet S.J., De Bosscher K. Glucocorticoid receptors: finding the middle ground. J Clin Invest. 2017; 127: 1136–1145.
  271. Petta I., Dejager L., Ballegeer M., et al. The interactome of the glucocorticoid receptor and its influence on the actions of glucocorticoids in combatting inflammatory and infectious diseases. Microbiol Mol Biol Rev. 2016; 80: 495–522.
  272. Paragliola R.M., Papi G., Pontecorvi Aж, et al. Treatment with synthetic glucocorticoids and the hypothalamus-pituitary-adrenal axis. Int J Mol Sci. 2017; 18: 1–7.
  273. Suh S., Park M.K. Glucocorticoid-induced diabetes mellitus: an important but overlooked problem. Endocrinol Metab (Seoul). 2017; 32: 180–189.
  274. Buckley L., Humphrey M.B. Glucocorticoid-induced osteoporosis. N Engl J Med. 2018; 379: 2547–2556.
  275. Buckley L., Guyatt G., Fink H.A., et al. American College of Rheumatology guideline for the prevention and treatment of glucocorticoid-induced osteoporosis. Arthritis Rheumatol. 2017; 69: 1521–1537.
  276. Gray J.D., Kogan J.F., Marrocco J., et al. Genomic and epigenomic mechanisms of glucocorticoids in the brain. Nat Rev Endocrinol. 2017; 13: 661–673.
  277. MacKenzie C.R., Goodman S.M. Stress dose steroids: myths and perioperative medicine. Curr Rheumatol Rep. 2016; 18: 1–5.
  278. Joseph R.M., Hunter A.L., Ray D.W., et al. Systemic glucocorticoid therapy and adrenal insufficiency in adults: a systematic review. Semin Arthritis Rheum. 2016; 46: 133–141.
  279. Broersen L.H., Pereira A.M., J?rgensen J.O., et al. Adrenal insufficiency in corticosteroids use: systematic review and meta-analysis. J Clin Endocrinol Metab. 2015; 100: 2171–2180.
  280. Guerrero P?rez F., Marengo A.P., Villabona Artero C.V. The unresolved riddle of glucocorticoid withdrawal. J Endocrinol Invest. 2017; 40: 1175–1181.
  281. Hu C., Lu L., Wan J.P., et al. The pharmacological mechanisms and therapeutic activities of hydroxychloroquine in rheumatic and related diseases. Curr Med Chem. 2017; 24: 2241–2249.
  282. Fernandez A.P. Updated recommendations on the use of hydroxychloroquine in dermatologic practice. J Am Acad Dermatol. 2017; 76: 1176–1182.
  283. Yusuf I.H., Sharma S., Luqmani R., et al. Hydroxychloroquine retinopathy. Eye (Lond). 2017; 31: 828–845.
  284. Chatzidionysiou K., Emamikia S., Nam J., et al. Efficacy of glucocorticoids, conventional and targeted synthetic disease-modifying antirheumatic drugs: a systematic literature review informing the 2016 update of the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis. 2017; 76: 1102–1107.
  285. Conway R., Carey J.J. Risks of liver disease in methotrexate treated patients. World J Hepatol. 2017; 9: 1092–1100.
  286. Zhang Y., Zhang R. Recent advances in analytical methods for the therapeutic drug monitoring of immunosuppressive drugs. Drug Test Anal. 2018; 10: 81–94.
  287. Hanauer S.B., Sandborn W.J., Lichtenstein G.R. Evolving considerations for thiopurine therapy for inflammatory bowel diseases—a clinical practice update: commentary. Gastroenterology. 2019; 156: 36–42.
  288. Shrestha B.M. Two decades of tacrolimus in renal transplant: basic science and clinical evidences. Exp Clin Transplant. 2017; 15: 1–9.
  289. McNerney M.E., Godley L.A., Le Beau M.M. Therapy-related myeloid neoplasms: when genetics and environment collide. Nat Rev Cancer. 2017; 17: 513–527.
  290. Mary J., De Bandt M., Lukas C., et al. Triple oral therapy versus antitumor necrosis factor plus metho- trexate (MTX) in patients with rheumatoid arthritis and inadequate response to MTX: a systematic literature review. J Rheumatol. 2017; 44: 773–779.
  291. Donahue K.E., Gartlehner G., Schulman E.R., et al. AHRQ comparative effectiveness reviews. Drug therapy for early rheumatoid arthritis: a systematic review update. Rockville (MD): Agency for Healthcare Research and Quality (US); 2018.
  292. Emery P., Pope J.E., Kruger K., et al. Efficacy of monotherapy with biologics and JAK inhibitors for the treatment of rheumatoid arthritis: a systematic review. Adv Ther. 2018; 35: 1535–1563.
  293. Colombel J.F., Sandborn W.J., Reinisch W., et al. Infliximab, azathioprine, or combination therapy for Crohn’s disease. N Engl J Med. 2010; 362: 1383–1395.
  294. Fukushima K., Sugita A., Futami K., et al. Postoperative therapy with infliximab for Crohn’s disease: a 2-year prospective randomized multicenter study in Japan. Surg Today. 2018; 48: 584–590.
  295. Ridker P.M., Everett B.M., Thuren T., et al. Antiinflammatory therapy with canakinumab for athero- sclerotic disease. N Engl J Med. 2017; 377: 1119–1131.
  296. Simpson E.L., Bieber T., Guttman-Yassky E., et al. Two phase 3 trials of dupilumab versus placebo in atopic dermatitis. N Engl J Med. 2017; 375: 2335–2348.
  297. Pavord I.D., Chanez P., Criner G.T., et al. Mepolizumab for eosinophilic chronic obstructive pulmonary disease. N Engl J Med. 2017; 377: 1613–1629.
  298. Stone J.H., Tuckwell K., Dimonaco S., et al. Trial of tocilizumab in giant-cell arteritis. N Engl J Med. 2017; 377: 317–328.
  299. Griffiths C.E., Strober B.E., van de Kerkhof P., et al. Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis. N Engl J Med. 2010; 362: 118–128.
  300. ACCESS Trial Group. Treatment of lupus nephritis with abatacept: the Abatacept and Cyclophos- phamide Combination Efficacy and Safety Study. Arthritis Rheumatol. 2014; 66: 3096–3104.
  301. Singh J.A., Hossain A., Tanjong Ghogomu E., et al. Biologics or tofacitinib for people with rheumatoid arthritis unsuccessfully treated with biologics: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2017; 3: CD012591.
  302. Beck A., Goetsch L., Dumontet C., et al. Strategies and challenges for the next generation of antibody- drug conjugates. Nat Rev Drug Discov. 2017; 16: 315–337.
  303. Lim W.A., June C.H. The principles of engineering immune cells to treat cancer. Cell. 2017; 168: 724–740.
  304. June C.H., Sadelain M. Chimeric antigen receptor therapy. N Engl J Med. 2018; 379: 64–73.
  305. Saccomanno B., Tibaldi J., Minoia F., et al. Predictors of effectiveness of anakinra in systemic juvenile idiopathic arthritis. J Rheumatol. 2019. [Предварительная электронная публикация.]
  306. Herwerth M., Hemmer B. Daclizumab for the treatment of relapsing-remitting multiple sclerosis. Expert Opin Biol Ther. 2017; 17: 747–753.
  307. McCracken J.L., Veeranki S.P., Ameredes B.T., et al. Diagnosis and management of asthma in adults: a review. JAMA. 2017; 318: 279–290.
  308. Schwartz D.M., Bonelli M., Gadina M., et al. Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases. Nat Rev Rheumatol. 2016; 12: 25–36.
  309. June R.R., Olsen N.J. Room for more IL-6 blockade? Sarilumab for the treatment of rheumatoid arthritis. Expert Opin Biol Ther. 2016; 16: 1303–1309.
  310. Monin L., Gaffen S.L. Interleukin 17 family cytokines: signaling mechanisms, biological activities, and therapeutic implications. Cold Spring Harb Perspect Biol. 2018; 10: 1–20.
  311. Corren J., Parnes J.R., Wang L., et al. Tezepelumab in adults with uncontrolled asthma. N Engl J Med. 2017; 377: 936–946.
  312. Kaplan A.P., Gim?nez-Arnau A.M., Saini S.S. Mechanisms of action that contribute to efficacy of omali- zumab in chronic spontaneous urticaria. Allergy. 2017; 72: 519–533.
  313. Zhang K., Lu Y., Harley K.T., et al. Atypical hemolytic uremic syndrome: a brief review. Hematol Rep. 2017; 9: 62–67.
  314. Park J.K., Fava A., Carrino J., et al. Association of acroosteolysis with enhanced osteoclastogenesis and higher blood levels of vascular endothelial growth factor in systemic sclerosis. Arthritis Rheumatol. 2016; 68: 201–209.
  315. Cai S., Yang Q., Li X., et al. The efficacy and safety of aflibercept and conbercept in diabetic macular edema. Drug Des Devel Ther. 2018; 12: 3471–3483.
  316. Lu C.S., Lin J.K., Chen W.S., et al. Intraperitoneal ziv-aflibercept effectively manages refractory ascites in colorectal cancer patients. Oncotarget. 2017; 8: 36707–36715.
  317. Thong B., Olsen N.J. Systemic lupus erythematosus diagnosis and management. Rheumatology (Oxford). 2017; 56 (suppl_1): i3–i13.
  318. Davis L.S., Reimold A.M. Research and therapeutics-traditional and emerging therapies in systemic lupus erythematosus. Rheumatology (Oxford). 2017; 56 (suppl_1): i100–i113.
  319. Taylor A., Westwood J.P., Laskou F., et al. Thrombopoetin receptor agonist therapy in thrombocyto- penia: ITP and beyond. Br J Haematol. 2017; 177: 475–480.
  320. Veale D.J., McGonagle D., McInnes I.B., et al. The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis. Rheumatology (Oxford). 2019; 58: 197–205.
  321. Cherkin D.C., Sherman K.J., Balderson B.H., et al. Effect of Mindfulness-based stress reduction vs cognitive behavioral therapy or usual care on back pain and functional limitations in adults with chronic low back pain: a randomized clinical trial. JAMA. 2016; 315: 1240–1249.
  322. Kuyken W., Hayes R., Barrett B., et al. Effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse or recurrence (PREVENT): a randomised controlled trial. Lancet. 2015; 386: 63–73.
  323. Huang Z.G., Feng Y.H., Li Y.H., et al. Systematic review and meta-analysis: Tai Chi for preventing falls in older adults. BMJ Open. 2017; 7: 1–8.
  324. Wang C., Bannuru R., Ramel J., et al. Tai chi on psychological well-being: systematic review and meta-analysis. BMC Complement Altern Med. 2010; 10: 1–16.
  325. Cramer H., Haller H., Lauche R., et al. A systematic review and meta-analysis of yoga for hypertension. Am J Hypertens. 2014; 27: 1146–1151.
  326. Cramer H., Lauche R., Langhorst J., et al. Yoga for depression: a systematic review and meta-analysis. Depress Anxiety. 2013; 30: 1068–1083.
  327. Kong L.J., Zhan H.S., Cheng Y.W., et al. Massage therapy for neck and shoulder pain: a systematic review and meta-analysis. Evid Based Complement Alternat Med. 2013; 2013: 1–10.
  328. Paige N.M., Miake-Lye I.M., Booth M.S., et al. Association of spinal manipulative therapy with clinical benefit and harm for acute low back pain: systematic review and meta-analysis. JAMA. 2017; 317: 1451–1460.
  329. Cheong K.B., Zhang J.P., Huang Y., et al. The effectiveness of acupuncture in prevention and treatment of postoperative nausea and vomiting — a systematic review and meta-analysis. PLoS ONE. 2013; 8: 1–17.
  330. Panahi Y., Rahimnia A.R., Sharafi M., et al. Curcuminoid treatment for knee osteoarthritis: a randomized double-blind placebo-controlled trial. Phytother Res. 2014; 28: 1625–1631.
  331. Liyanage T., Ninomiya T., Wang A., et al. Effects of the Mediterranean diet on cardiovascular outcomes — a systematic review and meta-analysis. PLoS ONE. 2016; 11: 1–11.
  332. Rycroft-Malone J., Gradinger F., Griffiths H.O., et al. Accessibility and implementation in the UK NHS Services of an effective depression relapse prevention programme: learning from mindfulness-based cognitive therapy through a mixed-methods study. Southampton (UK): NIHR Journals Library; 2017.
  333. Kachan D., Olano H., Tannenbaum S.L., et al. Prevalence of mindfulness practices in the US Workforce: National Health Interview Survey. Prev Chronic Dis. 2017; 14: 1–12.
  334. Park S.H., Han K.S. Blood pressure response to meditation and yoga: a systematic review and meta- analysis. J Altern Complement Med. 2017; 23: 685–695.
  335. Miller K.M., Chad-Friedman E., Haime V., et al. The effectiveness of a brief mind-body intervention for treating depression in community health center patients. Glob Adv Health Med. 2015; 4: 30–35.
  336. Laird K.T., Paholpak P., Roman M., et al. Mind-body therapies for late-life mental and cognitive health. Curr Psychiatry Rep. 2018; 20: 1–12.
  337. Majeed M.H., Ali A.A., Sudak D.M. Mindfulness-based interventions for chronic pain: evidence and applications. Asian J Psychiatr. 2018; 32: 79–83.
  338. Shipton E.A. Physical therapy approaches in the treatment of low back pain. Pain Ther. 2018; 7: 127–137.
  339. Qaseem A., Wilt T.J., McLean R.M., et al. Clinical guidelines committee of the American college of physicians. Noninvasive treatments for acute, Subacute, and chronic low back pain: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2017; 166: 514–530.
  340. PDQ Integrative, Alternative, and Complementary Therapies Editorial Board. Acupuncture (PDQ): health professional version. PDQ Cancer Information Summaries. Bethesda (MD): National Cancer Institute (US); 2002. https://www.ncbi.nlm.nih.gov/books/NBK65714/. Дата обращения: 4 июня 2019 г.
  341. Geller A.I., Shehab N., Weidle N.J., et al. Emergency department visits for adverse events related to dietary supplements. N Engl J Med. 2015; 373: 1531–1540.
  342. Brown A.C. An overview of herb and dietary supplement efficacy, safety and government regulations in the United States with suggested improvements. Part 1 of 5 series. Food Chem Toxicol. 2017; 107 (Pt A): 449–471.
  343. Cho J.A., Chinnapen DJF. Targeting friend and foe: emerging therapeutics in the age of gut microbiome and disease. J Microbiol. 2018; 56: 183–188.
  344. Hojsak I. Probiotics in functional gastrointestinal disorders. Adv Exp Med Biol. 2018.
  345. Zhao R, Xu Z, Zhao M. Antiresorptive agents increase the effects of exercise on preventing post­menopausal bone loss in women: a meta-analysis. PLoS ONE. 2015; 10: 1–16.
  346. Williamson JD, Supiano MA, Applegate WB, et al. Intensive vs standard blood pressure control and cardiovascular disease outcomes in adults aged ?75 years: a randomized clinical trial. JAMA. 2016; 315: 2673–2682.
  347. Savarese G, Gotto AM Jr, Paolillo S, et al. Benefits of statins in elderly subjects without established cardiovascular disease: a meta-analysis. J Am Coll Cardiol. 2013; 62: 2090–2099.
  348. Kutner JS, Blatchford PJ, Taylor DH Jr, et al. Safety and benefit of discontinuing statin therapy in the setting of advanced, life-limiting illness: a randomized clinical trial. JAMA Intern Med. 2015; 175: 691–700.
  349. Pahor M, Guralnik JM, Ambrosius WT, et al. Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial. JAMA. 2014; 311: 2387–2396.
  350. Lai CC, Tu YK, Wang TG, et al. Effects of resistance training, endurance training and whole-body vibration on lean body mass, muscle strength and physical performance in older people: a systematic review and network meta-analysis. Age Ageing. 2018; 47: 367–373.
  351. Snyder PJ, Bhasin S, Cunningham GR, et al. Effects of testosterone treatment in older men. N Engl J Med. 2016; 374: 611–624.
  352. McNeil JJ, Woods RL, Nelson MR, et al. Effect of aspirin on disability-free survival in the healthy elderly. N Engl J Med. 2018; 379: 1499–1508.
  353. McNeil JJ, Nelson MR, Woods RL, et al. Effect of aspirin on all-cause mortality in the healthy elderly. N Engl J Med. 2018; 379: 1519–1528.
  354. Woolf SH, Chapman DA, Buchanich JM, et al. Changes in midlife death rates across racial and ethnic groups in the United States: systematic analysis of vital statistics. BMJ. 2018; 362: 1–16.
  355. Franceschi C, Garagnani P, Morsiani C, et al. The continuum of aging and age-related diseases: common mechanisms but different rates. Front Med (Lausanne). 2018; 5: 1–23.
  356. Murphy SL, Xu J, Kochanek KD, et al. Mortality in the United States, 2017. NCHS Data Brief. 2018; 1–8.
  357. Qui?ones AR, Markwardt S. Botoseneanu A. Multimorbidity combinations and disability in older adults. J Gerontol A Biol Sci Med Sci. 2016; 71: 823–830.
  358. Cruz-Jentoft AJ, Kiesswetter E, Drey M, et al. Nutrition, frailty, and sarcopenia. Aging Clin Exp Res. 2017; 29: 43–48.
  359. Vetrano DL, Palmer K, Marengoni A, et al. Frailty and multimorbidity: a systematic review and meta-analysis. J Gerontol A Biol Sci Med Sci. 2019; 74: 659–666.
  360. Klausen HH, Petersen J, Bandholm T, et al. Association between routine laboratory tests and long-term mortality among acutely admitted older medical patients: a cohort study. BMC Geriatr. 2017; 17: 1–14.
  361. Dato S, Rose G, Crocco P, et al. The genetics of human longevity: an intricacy of genes, environment, culture and microbiome. Mech Ageing Dev. 2017; 165: 147–155.
  362. Odden MC, Pletcher MJ, Coxson PG, et al. Cost-effectiveness and population impact of statins for primary prevention in adults aged 75 years or older in the United States. Ann Intern Med. 2015; 162: 533–541.
  363. Chou R, Dana T, Bougatsos C, et al. Screening for impaired visual acuity in older adults: updated evidence report and systematic review for the US Preventative Services Task Force. JAMA. 2016; 315: 915–933.
  364. Bischoff-Ferrari HA, Dawson-Hughes B, Orav EJ, et al. Monthly high-dose vitamin D treatment for the prevention of functional decline: a randomized clinical trial. JAMA Intern Med. 2016; 176: 175–183.
  365. Piper MA, Evans CV, Burda BU, et al. Screening for high blood pressure in adults: a systematic evidence review for the U.S. Preventive Services Task Force. Rockville (MD): Agency for Healthcare Research and Quality (US); 2014. (Evidence Syntheses, No. 121.). https://www.ncbi.nlm.nih.gov/books/NBK269495/. Accessed June 5, 2019.
  366. McNeil JJ, Woods RL, Nelson MR, et al. Effect of aspirin on disability-free survival in the healthy elderly. N Engl J Med. 2018; 379: 1499–1508.
  367. Ellis G, Gardner M, Tsiachristas A, et al. Comprehensive geriatric assessment for older adults admitted to hospital. Cochrane Database Syst Rev. 2017; 9: CD006211.
  368. Partridge JS, Harari D, Martin FC, et al. Randomized clinical trial of comprehensive geriatric assessment and optimization in vascular surgery. Br J Surg. 2017; 104: 679–687.
  369. Tang V, Boscardin WJ, Stijacic-Cenzer I, et al. Time to benefit for colorectal cancer screening: survival meta-analysis of flexible sigmoidoscopy trials. BMJ. 2015; 350: 1–5.
  370. Arias E, Heron M, Xu J. United States life tables, 2012. Natl Vital Stat Rep. 2016; 65: 1–65.
  371. Jennings LA, Palimaru A, Corona MG, et al. Patient and caregiver goals for dementia care. Qual Life Res. 2017; 26: 685–693.
  372. Siu AL, Bibbins-Domingo K, Grossman DC, et al. Screening for impaired visual acuity in older adults: US preventive services task force recommendation statement. JAMA. 2016; 315: 908–914.
  373. Folmer RL, Vachhani J, McMillan GP, et al. Validation of a computer-administered version of the digits-in-noise test for hearing screening in the United States. J Am Acad Audiol. 2017; 28: 161–169.
  374. Wang Z, Dong B. Screening for cognitive impairment in geriatrics. Clin Geriatr Med. 2018; 34: 515–536.
  375. Siu AL, Bibbins-Domingo K, Grossman DC, et al. Screening for depression in adults: US Preventive Services Task Force recommendation statement. JAMA. 2016; 315: 380–387.
  376. Jennings LA, Reuben DB, Kim SB, et al. Targeting a high-risk group for fall prevention: strategies for health plans. Am J Manag Care. 2015; 21: e519–e526.
  377. Talarska D, Struga?a M, Szewczyczak M, et al. Is independence of older adults safe considering the risk of falls? BMC Geriatr. 2017; 17: 1–7.
  378. Park SH. Tools for assessing fall risk in the elderly: a systematic review and meta-analysis. Aging Clin Exp Res. 2018; 30: 1–16.
  379. LeFevre ML. Screening for vitamin D deficiency in adults: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2015; 162: 133–140.
  380. Buta BJ, Walston JD, Godino JG, et al. Frailty assessment instruments: systematic characterization of the uses and contexts of highly-cited instruments. Ageing Res Rev. 2016; 26: 53–61.
  381. Gilbert T, Neuburger J, Kraindler J, et al. Development and validation of a Hospital Frailty Risk Score focusing on older people in acute care settings using electronic hospital records: an observational study. Lancet. 2018; 391: 1775–1782.
  382. Seib CD, Rochefort H, Chomsky-Higgins K, et al. Association of patient frailty with increased morbidity after common ambulatory general surgery operations. JAMA Surg. 2018; 153: 160–168.
  383. Bavishi C, Bangalore S, Messerli FH. Outcomes of intensive blood pressure lowering in older hypertensive patients. J Am Coll Cardiol. 2017; 69: 486–493.
  384. Moonen JE, Foster-Dingley JC, de Ruijter W, et al. Effect of discontinuation of antihypertensive treatment in elderly people on cognitive functioning — the DANTE study leiden: a randomized clinical trial. JAMA Intern Med. 2015; 175: 1622–1630.
  385. Teng M, Lin L, Zhao YJ, et al. Statins for primary prevention of cardiovascular disease in elderly patients: systematic review and meta-analysis. Drugs Aging. 2015; 32: 649–661.
  386. Kutner JS, Blatchford PJ, Taylor DH Jr, et al. Safety and benefit of discontinuing statin therapy in the setting of advanced, life-limiting illness: a randomized clinical trial. JAMA Intern Med. 2015; 175: 691–700.
  387. McNeil JJ, Nelson MR, Woods RL, et al. Effect of aspirin on all-cause mortality in the healthy elderly. N Engl J Med. 2018; 379: 1519–1528.
  388. McNeil JJ, Woods RL, Nelson MR, et al. Effect of aspirin on disability-free survival in the healthy elderly. N Engl J Med. 2018; 379: 1499–1508.
  389. Howden EJ, Sarma S, Lawley JS, et al. Reversing the cardiac effects of sedentary aging in middle age — a randomized controlled trial: implications for heart failure prevention. Circulation. 2018; 137: 1549–1560.
  390. Cereda E, Klersy C, Serioli M, et al. A nutritional formula enriched with arginine, zinc, and antioxidants for the healing of pressure ulcers: a randomized trial. Ann Intern Med. 2015; 162: 167–174.
  391. Reid IR, Horne AM, Mihov B, et al. Fracture prevention with zoledronate in older women with osteopenia. N Engl J Med. 2018; 379: 2407–2416.
  392. Cameron ID, Fairhall N, Langron C, et al. A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial. BMC Med. 2013; 11: 1–10.
  393. Gine-Garriga M, Roque-Figuls M, Coll-Planas L, et al. Physical exercise interventions for improving performance-based measures of physical function in community-dwelling, frail older adults: a systematic review and meta-analysis. Arch Phys Med Rehabil. 2014; 95: 753–769.
  394. Pahor M, Guralnik JM, Ambrosius WT, et al. Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial. JAMA. 2014; 311: 2387–2396.
  395. Guirguis-Blake JM, Michael YL, Perdue LA, et al. Interventions to prevent falls in older adults: updated evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2018; 319: 1705–1716.
  396. Tricco AC, Thomas SM, Veroniki AA, et al. Comparisons of interventions for preventing falls in older adults: a systematic review and meta-analysis. JAMA. 2017; 318: 1687–1699.
  397. Ferrante LE, Pisani MA, Murphy TE, et al. Functional trajectories among older persons before and after critical illness. JAMA Intern Med. 2015; 175: 523–529.
  398. Qaseem A, Wilt TJ, McLean RM, et al. Noninvasive treatments for acute, subacute, and chronic low back pain: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2017; 166: 514–530.
  399. Juraschek SP, Daya N, Appel LJ, et al. Orthostatic hypotension in middle-age and risk of falls. Am J Hypertens. 2017; 30: 188–195.
  400. Odden MC, Pletcher MJ, Coxson PG, et al. Cost-effectiveness and population impact of statins for primary prevention in adults aged 75 years or older in the United States. Ann Intern Med. 2015; 162: 533–541.
  401. Forman DE, Maurer MS, Boyd C, et al. Multimorbidity in older adults with cardiovascular disease. J Am Coll Cardiol. 2018; 71: 2149–2161.
  402. Qaseem A, Mir TP, Starkey M, et al. Risk assessment and prevention of pressure ulcers: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2015; 162: 359–369.
  403. Qaseem A, Humphrey LL, Forciea MA, et al. Treatment of pressure ulcers: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2015; 162: 370–379.
  404. Buta BJ, Walston JD, Godino JG, et al. Frailty assessment instruments: systematic characterization of the uses and contexts of highly-cited instruments. Ageing Res Rev. 2016; 26: 53–61.
  405. Gilbert T, Neuburger J, Kraindler J, et al. Development and validation of a hospital frailty risk score focusing on older people in acute care settings using electronic hospital records: an observational study. Lancet. 2018; 391: 1775–1782.
  406. Muscedere J, Waters B, Varambally A, et al. The impact of frailty on intensive care unit outcomes: a systematic review and meta-analysis. Intensive Care Med. 2017; 43: 1105–1122.
  407. Seib CD, Rochefort H, Chomsky-Higgins K, et al. Association of patient frailty with increased morbidity after common ambulatory general surgery operations. JAMA Surg. 2018; 153: 160–168.
  408. Ward MAR, Alenazi A, Delisle M, et al. The impact of frailty on acute care general surgery patients: a systematic review. J Trauma Acute Care Surg. 2019; 86: 148–154.
  409. Abel GA, Klepin HD. Frailty and the management of hematologic malignancies. Blood. 2018; 131: 515–524.
  410. Grossman DC, Curry SJ, Owens DK, et al. Interventions to prevent falls in community-dwelling older adults: US Preventive Services Task Force recommendation statement. JAMA. 2018; 319: 1696–1704.
  411. Imamura M, Williams K, Wells M, et al. Lifestyle interventions for the treatment of urinary incontinence in adults. Cochrane Database Syst Rev. 2015; 12: CD003505.
  412. Radzimi?ska A, Straczy?ska A, Weber-Rajek M, et al. The impact of pelvic floor muscle training on the quality of life of women with urinary incontinence: a systematic literature review. Clin Interv Aging. 2018; 13: 957–965.
  413. Qaseem A, Dallas P, Forciea MA, et al. Nonsurgical management of urinary incontinence in women: a clinical practice guideline from the American college of physicians. Ann Intern Med. 2014; 161: 429–440.
  414. Labrie J, Berghmans BL, Fischer K, et al. Surgery versus physiotherapy for stress urinary incontinence. N Engl J Med. 2013; 369: 1124–1133.
  415. Liu Z, Liu Y, Xu H, et al. Effect of electroacupuncture on urinary leakage among women with stress urinary incontinence: a randomized clinical trial. JAMA. 2017; 317: 2493–2501.
  416. Roe B, Flanagan L, Maden M. Systematic review of systematic reviews for the management of urinary incontinence and promotion of continence using conservative behavioural approaches in older people in care homes. J Adv Nurs. 2015; 71: 1464–1483.
  417. Dubeau CE, Kraus SR, Griebling TL, et al. Effect of fesoterodine in vulnerable elderly subjects with urgency incontinence: a double-blind, placebo controlled trial. J Urol. 2014; 191: 395–404.
  418. Drake MJ, Chapple C, Esen AA, et al. Efficacy and safety of mirabegron add-on therapy to solifenacin in incontinent overactive bladder patients with an inadequate response to initial 4-week solifenacin monotherapy: a randomised double-blind multicentre phase 3b study (BESIDE). Eur Urol. 2016; 70: 136–145.
  419. Rahn DD, Ward RM, Sanses TV, et al. Vaginal estrogen use in postmenopausal women with pelvic floor disorders: systematic review and practice guidelines. Int Urogynecol J. 2015; 26: 3-13
  420. Amundsen CL, Richter HE, Menefee SA, et al. OnabotulinumtoxinA vs sacral neuromodulation on refractory urgency urinary incontinence in women: a randomized clinical trial. JAMA. 2016; 316: 1366–1374.
  421. Ginsberg DA, Drake MJ, Kaufmann A, et al. Long-term treatment with onabotulinumtoxina results in consistent, durable improvements in health related quality of life in patients with overactive bladder. J Urol. 2017; 198: 897–904.
  422. Rubin EB, Buehler AE, Halpern SD. States worse than death among hospitalized patients with serious illnesses. JAMA Intern Med. 2016; 176: 1557–1559.
  423. Vaughan CP, Markland AD, Smith PP, et al. Report and research agenda of the American geriatrics society and national institute on aging bedside-to-bench conference on urinary incontinence in older adults: a translational research agenda for a complex geriatric syndrome. J Am Geriatr Soc. 2018; 66: 773–782.
  424. Camoes J, Coelho A, Castro-Diaz D, et al. Lower urinary tract symptoms and aging: the impact of chronic bladder ischemia on overactive bladder syndrome. Urol Int. 2015; 95: 373–379.
  425. Vahabi B, Wagg AS, Rosier P, et al. Can we define and characterize the aging lower urinary tract?-ICI-RS 2015. Neurourol Urodyn. 2017; 36: 854–858.
  426. Gormley EA, Lightner DJ, Faraday M, et al. Diagnosis and treatment of overactive bladder (non-neurogenic) in adults: AUA/SUFU guideline amendment. J Urol. 2015; 193: 1572–1580.
  427. Lukacz ES, Santiago-Lastra Y, Albo ME, et al. Urinary incontinence in women: a review. JAMA. 2017; 318: 1592–1604.
  428. Robert M, Ross S. No. 186-conservative management of urinary incontinence. J Obstet Gynaecol Can. 2018; 40: e119–e125.
  429. Hagan KA, Erekson E, Austin A, et al. A prospective study of the natural history of urinary incontinence in women. Am J Obstet Gynecol. 2018; 218: e501–e508.
  430. Capobianco G, Madonia M, Morelli S, et al. Management of female stress urinary incontinence: a care pathway and update. Maturitas. 2018; 109: 32–38.
  431. Culbertson S, Davis AM. Nonsurgical management of urinary incontinence in women. JAMA. 2017; 317: 79–80.
  432. Andersson K-E, Cardozo L, Lee K-S, et al. Pharmacological treatment of urinary incontinence. In: Abrams P, Cardozo L, Wagg A, Wein AJ, eds. Incontinence. 6th ed. ICS/ICUD Publishers; 2017: 805–957.
  433. Serati M, Andersson KE, Dmochowski R, et al. Systematic review of combination drug therapy for non-neurogenic lower urinary tract symptoms. Eur Urol. 2019; 75: 129–168.
  434. Kobashi KC, Albo ME, Dmochowski RR, et al. Surgical treatment of female stress urinary incontinence: AUA/SUFU guideline. J Urol. 2017; 198: 875–883.
  435. Capobianco G, Azzena A, Saderi L, et al. Urolastic®, a new bulking agent for treatment of stress urinary incontinence: a systematic review and meta-analysis. Int Urogynecol J. 2018; 29: 1239–1247.
  436. Schneider MP, Gross T, Bachmann LM, et al. Tibial nerve stimulation for treating neurogenic lower urinary tract dysfunction: a systematic review. Eur Urol. 2015; 68: 859–867.
  437. Richter HE, Amundsen CL, Erickson SW, et al. Characteristics associated with treatment response and satisfaction in women undergoing onabotulinumtoxina and sacral neuromodulation for refractory urgency urinary incontinence. J Urol. 2017; 198: 890–896.
  438. Fuchs JS, Shakir N, McKibben MJ, et al. Prolonged duration of incontinence for men before initial anti-incontinence surgery: an opportunity for improvement. Urology. 2018; 119: 149–154.
  439. Clyne B, Smith SM, Hughes CM, et al. Effectiveness of a multifaceted intervention for potentially inappropriate prescribing in older patients in primary care: a cluster-randomized controlled trial (OPTI-SCRIPT study). Ann Fam Med. 2015; 13: 545–553.
  440. O’Connor MN, O’Sullivan D, Gallagher PF, et al. Prevention of hospital-acquired adverse drug reactions in older people using screening tool of older persons’ prescriptions and screening tool to alert to right treatment criteria: a cluster randomized controlled trial. J Am Geriatr Soc. 2016; 64: 1558–1566.
  441. O’Sullivan D, O’Mahony D, O’Connor MN, et al. Prevention of adverse drug reactions in hospitalised older patients using a software-supported structured pharmacist intervention: a cluster randomised controlled trial. Drugs Aging. 2016; 33: 63–73.
  442. Resnick SM, Matsumoto AM, Stephens-Shields AJ, et al. Testosterone treatment and cognitive function in older men with low testosterone and age-associated memory impairment. JAMA. 2017; 317: 717–727.
  443. Inouye SK. Enhancing cognitive aging: clinical highlights of a report from the institute of medicine. Ann Intern Med. 2015; 163: 307–310.
  444. Maharani A, Dawes P, Nazroo J, et al. Visual and hearing impairments are associated with cognitive decline in older people. Age Ageing. 2018; 47: 575–581.
  445. Alzheimer’s Association. 2019 Alzheimer’s disease facts and figures. Alzheimers Dement. 2019; 3: 321–387.
  446. Han R, Tang Z, Ma L. Related factors of cognitive impairment in community-dwelling older adults in Beijing longitudinal study of aging. Aging Clin Exp Res. 2019; 31: 95–100.
  447. Kotwal AA, Kim J, Waite L, et al. Social function and cognitive status: results from a US nationally representative survey of older adults. J Gen Intern Med. 2016; 31: 854–862.
  448. Wimmer BC, Cross AJ, Jokanovic N, et al. Clinical outcomes associated with medication regimen complexity in older people: a systematic review. J Am Geriatr Soc. 2017; 65: 747–753.
  449. Kok RM, Reynolds CF 3rd. Management of depression in older adults: a review. JAMA. 2017; 317: 2114–2122.
  450. Nerenberg KA, Zarnke KB, Leung AA, et al. Hypertension Canada’s 2018 guidelines for diagnosis, risk assessment, prevention, and treatment of hypertension in adults and children. Can J Cardiol. 2018; 34: 506–525.
  451. Hshieh TT, Yue J, Oh E, et al. Effectiveness of multicomponent nonpharmacological delirium interventions: a meta-analysis. JAMA Intern Med. 2015; 175: 512–520.
  452. Chen CC, Li HC, Liang JT, et al. Effect of a modified hospital elder life program on delirium and length of hospital stay in patients undergoing abdominal surgery: a cluster randomized clinical trial. JAMA Surg. 2017; 152: 827–834.
  453. Kolanowski A, Fick D, Litaker M, et al. Effect of cognitively stimulating activities on symptom management of delirium superimposed on dementia: a randomized controlled trial. J Am Geriatr Soc. 2016; 64: 2424–2432.
  454. Siddiqi N, Harrison JK, Clegg A, et al. Interventions for preventing delirium in hospitalised non-ICU patients. Cochrane Database Syst Rev. 2016; 3: CD005563.
  455. Perkisas SM, Vandewoude MF. Ramelteon for prevention of delirium in hospitalized older patients. JAMA. 2015; 313: 1745–1746.
  456. Su X, Meng ZT, Wu XH, et al. Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery: a randomised, double-blind, placebo-controlled trial. Lancet. 2016; 388: 1893–1902.
  457. Skrobik Y, Duprey MS, Hill NS, et al. Low-dose nocturnal dexmedetomidine prevents ICU delirium. A randomized, placebo-controlled trial. Am J Respir Crit Care Med. 2018; 197: 1147–1156.
  458. van den Boogaard M, Slooter AJC, Bruggemann RJM, et al. Effect of haloperidol on survival among critically ill adults with a high risk of delirium: the REDUCE randomized clinical trial. JAMA. 2018; 319: 680–690.
  459. Girard TD, Exline MC, Carson SS, et al. Haloperidol and ziprasidone for treatment of delirium in critical illness. N Engl J Med. 2018; 379: 2506–2516.
  460. Agar MR, Lawlor PG, Quinn S, et al. Efficacy of oral risperidone, haloperidol, or placebo for symptoms of delirium amont patients in palliative care: a randomized clinical trial. JAMA Intern Med. 2017; 177: 34–42.
  461. Neufeld KJ, Yue J, Robinson TN, et al. Antipsychotic medication for prevention and treatment of delirium in hospitalized adults: a systematic review and meta-analysis. J Am Geriatr Soc. 2016; 64: 705–714.
  462. Hui D, Frisbee-Hume S, Wilson A, et al. Effect of lorazepam with haloperidol vs haloperidol alone on agitated delirium in patients with advanced cancer receiving palliative care: a randomized clinical trial. JAMA. 2017; 318: 1047–1056.
  463. Oh ES, Fong TG, Hshieh TT, et al. Delirium in older persons: advances in diagnosis and treatment. JAMA. 2017; 318: 1161–1174.
  464. Watt J, Tricco AC, Talbot-Hamon C, et al. Identifying older adults at risk of delirium following elective surgery: a systematic review and meta-analysis. J Gen Intern Med. 2018; 33: 500–509.
  465. Cavallari M, Dai W, Guttmann CRG, et al. Longitudinal diffusion changes following postoperative delirium in older people without dementia. Neurology. 2017; 89: 1020–1027.
  466. Marcantonio ER. Delirium in hospitalized older adults. N Engl J Med. 2017; 377: 1456–1466.
  467. Rohatgi N, Weng Y, Bentley J, et al. Initiative for prevention and early identification of delirium in medical-surgical units: lessons learnt in the past five years. Am J Med. 2019. [Epub ahead of print.].
  468. Gleason LJ, Schmitt EM, Kosar CM, et al. Effect of delirium and other major complications on outcomes after elective surgery in older adults. JAMA Surg. 2015; 150: 1134–1140.
  469. Dharmarajan K, Swami S, Gou RY, et al. Pathway from delirium to death: potential in-hospital mediators of excess mortality. J Am Geriatr Soc. 2017; 65: 1026–1033.
  470. Inouye SK, Marcantonio ER, Kosar CM, et al. The short-term and long-term relationship between delirium and cognitive trajectory in older surgical patients. Alzheimers Dement. 2016; 12: 766–775.
  471. Okuyama T, Yoshiuchi K, Ogawa A, et al. Current pharmacotherapy does not improve severity of hypoactive delirium in patients with advanced cancer: pharmacological audit study of safety and efficacy in real world (Phase-R). Oncologist. 2019. [Epub ahead of print.].
  472. Chou R, Dana T, Blazina I, et al. Statins for prevention of cardiovascular disease in adults: evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2016; 316: 2008–2024.
  473. Lin JS, Piper MA, Perdue LA, et al. Screening for colorectal cancer: updated evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2016; 315: 2576–2594.
  474. Melnikow J, Henderson JT, Burda BU, et al. Screening for cervical cancer with high-risk human papilloma virus testing: updated evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2018; 320: 687–705.
  475. Fenton JJ, Weyrich MS, Durbin S, et al. Prostate-specific antigen-based screening for prostate cancer: evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2018; 319: 1914–1931.
  476. Center for Healthcare Policy and Research. Prostate-specific antigen–based screening for prostate cancer: a systematic evidence review for the U.S. Preventive Services Task Force. (Evidence syntheses, no. 154.) Rockville, MD: Agency for Healthcare Research and Quality, April 2017. AHRQ Publication No. 17-05229-EF-1.
  477. LeFevre ML. Screening for chlamydia and gonorrhea: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2014; 161: 902–910.
  478. Zheng SL, Roddick AJ. Association of aspirin use for primary prevention with cardiovascular events and bleeding events: a systematic review and meta-analysis. JAMA. 2019; 321: 277–287.
  479. Gartlehner G, Patel SV, Feltner C, et al. Hormone therapy for the primary prevention of chronic conditions in postmenopausal women evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2017; 318: 2234–2249.
  480. Krist AH, Wolff TA, Jonas DE, et al. Update on the methods of the U.S. Preventive Services Task Force: methods for understanding certainty and net benefit when making recommendations. Am J Prev Med. 2018; 54: 511–518.
  481. Siu AL, and the US Preventive Services Task Force (USPSTF). Screening for depression in adults: US Preventive Services Task Force recommendation statement. JAMA. 2016; 315: 380–387.
  482. American Heart Association, American College of Cardiology. Pooled Cohort Equations Cardio-vascular Risk Calculator. 2014. http://tools.acc.org/ASCVD-Risk-Estimator/. Accessed May 10, 2019.
  483. Bibbins-Domingo K, Grossman DC, Curry SJ, et al. Screening for colorectal cancer: US Preventive Services Task Force recommendation statement. /AMA. 2016; 315: 2564–2575.
  484. Myers ER, Moorman P, Gierisch JM, et al. Benefts and harms of breast cancer screening: a systematic review. JAMA. 2015; 314: 1615–1634.
  485. Siu AL. Screening for breast cancer: U.S. Preventive Services Task Force recommendation statement.Ann Intern Med. 2016; 164: 279–296.
  486. US Preventive Services Task Force. Screening for cervical cancer: US Preventive Services Task Force recommendation statement. JAMA. 2018; 320: 674–686.
  487. Bibbins-Domingo K, Grossman DC, Curry S], et al. Screening for gynecologic conditions with pelvic examination: US Preventive Services Task Force recommendation statement. JAMA. 2017; 317: 947–953.
  488. U.S. Preventative Services Task Force. Screening for prostate cancer: US Preventive Services Task Force recommendation statement. JAMA. 2018: 319: 1901-1913
  489. LeFevre ML. Screening for thyroid dysfunction: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2015; 162: 641–650.
  490. Selph S, Dana T, Blazina I, et al. Screening for type 2 diabetes mellitus: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med. 2015; 162: 765–776.
  491. Grossman DC, Bibbins-Domingo K, Curry SJ, et al. Behavioral counseling to promote a healthful diet and physical activity for cardiovascular disease prevention in adults without cardiovascular risk factors: US Preventive Services Task Force recommendation statement. AMA. 2017; 318: 167–174.
  492. Curry SJ, Krist AH, Owens DK, et al. Screening for intimate partner violence, elder abuse, and abuse of vulnerable adults: US Preventive Services Task Force final recommendation statement. JAMA. 2018; 320: 1678–1687.
  493. Kim DK, Riley LE, Harriman KH, et al. Advisory committee on immunization practices recom-mended immunization schedule for adults aged 19 years or older — United States, 2017. MMWR Morb Mortal Wkly Rep. 2017; 66: 136–138.
  494. Bibbins-Domingo K. Aspirin use for the primary prevention of cardiovascular disease and colorectal cancer: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2016; 164: 836–845.
  495. Bibbins-Domingo K, Whitlock E, Wolf T, et al. Developing recommendations for evidence-based clinical preventive services for diverse populations: methods of the U.S. Preventive Services Task Force. Ann Intern Med. 2017; 166: 565–571.
  496. Mabry-Hernandez IR, Curry SJ, Phillips WR, et al. U.S. Preventive Services Task Force priorities for prevention research. Am | Prev Med. 2018; 54: 595–S103.
  497. Zhao R, Feng F, Wang X. Exercise interventions and prevention of fall-related fractures in older people: a meta-analysis of randomized controlled trials. Int J Epidemiol. 2017; 46: 149–161.
  498. Lesinski M, Hortobagyi T, Muehlbauer T, et al. Effects of balance training on balance performance in healthy older adults: a systematic review and meta-analysis. Sports Med. 2015; 45: 1721–1738.
  499. Pahor M, Guralnik JM, Ambrosius WT, et al. Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial. JAMA. 2014; 311: 2387–2396.
  500. Northey JM, Cherbuin N, Pumpa KL, et al. Exercise interventions for cognitive function in adults older than 50: a systematic review with meta-analysis. Br J Sports Med. 2018; 52: 154–160.
  501. Lamb SE, Sheehan B, Atherton N, et al. Dementia and physical activity (DAPA) trial of moderate to high intensity exercise training for people with dementia: randomised controlled trial. BMJ. 2018; 361: 1–11.
  502. Borjesson M, Onerup A, Lundqvist S, et al. Physical activity and exercise lower blood pressure in individuals with hypertension: narrative review of 27 RCTs. Br J Sports Med. 2016; 50: 356–361.
  503. Mansi S, Milosavljevic S, Baxter GD, et al. A systematic review of studies using pedometers as an intervention for musculoskeletal diseases. BMC Musculoskelet Disord. 2014; 15: 1–13.
  504. Samdal GB, Eide GE, Barth T, et al. Effective behaviour change techniques for physical activity and healthy eating in overweight and obese adults; systematic review and meta-regression analyses. Int J Behav Nutr Phys Act. 2017; 14: 1–14.
  505. Buckingham SA, Taylor RS, Jolly K, et al. Home-based versus centre-based cardiac rehabilitation: abridged Cochrane systematic review and meta-analysis. Open Heart. 2016; 3: 1–15.
  506. Watson KB, Carlson SA, Gunn JP, et al. Physical inactivity among adults aged 50 years and older—United States, 2014. MMWR Morb Mortal Wkly Rep. 2016; 65: 954–958.
  507. U.S. Department of Health and Human Services. 2018 physical activity guidelines advisory committee scientific report. https://health.gov/sites/default/files/2019-09/PAG_Advisory_Committee_Report.pdf. Accessed May 10, 2019.
  508. Warburton DE, Bredin SS. Reflections on physical activity and health: what should we recommend? Can J Cardiol. 2016; 32: 495–504.
  509. Moore SC, Lee IM, Weiderpass E, et al. Association of leisure-time physical activity with risk of 26 types of cancer in 1.44 million adults. JAMA Intern Med. 2016; 176: 816–825.
  510. Zanuso S, Sacchetti M, Sundberg CJ, et al. Exercise in type 2 diabetes: genetic, metabolic and neuromuscular adaptations. A review of the evidence. Br J Sports Med. 2017; 51: 1533–1538.
  511. Ekelund U, Steene-Johannessen J, Brown WJ, et al. Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality? A harmonised meta-analysis of data from more than 1 million men and women. Lancet. 2016; 388: 1302–1310.
  512. Kraschnewski JL, Sciamanna CN, Poger JM, et al. Is strength training associated with mortality benefits? A 15 year cohort study of US older adults. Prev Med. 2016; 87: 121–127.
  513. Goodman JM, Burr JF, Banks L, et al. The acute risks of exercise in apparently healthy adults and relevance for prevention of cardiovascular events. Can J Cardiol. 2016; 32: 523–532.
  514. Piercy KL, Troiano RP, Ballard RM, et al. The physical activity guidelines for Americans. JAMA. 2018; 320: 2020–2028.
  515. Diaz KM, Howard VJ, Hutto B, et al. Patterns of sedentary behavior and mortality in U.S. middle-aged and older adults: a national cohort study. Ann Intern Med. 2017; 167: 465–475.
  516. Hivert MF, Arena R, Forman DE, et al. Medical training to achieve competency in lifestyle counseling: an essential foundation for prevention and treatment of cardiovascular diseases and other chronic medical conditions: a scientific statement from the American heart association. Circulation. 2016; 134: e308–e327.
  517. Grossman DC, Bibbins-Domingo K, Curry SJ, et al. Behavioral counseling to promote a healthful diet and physical activity for cardiovascular disease prevention in adults without cardiovascular risk factors: US preventive services task force recommendation statement. JAMA. 2017; 318: 167–174.
  518. Zubin Maslov P, Schulman A, Lavie CJ, et al. Personalized exercise dose prescription. Eur Heart J. 2018; 39: 2346–2355.
  519. Boff R.M., Liboni R.P.A., Batista I.P.A., et al. Weight loss interventions for overweight and obese adolescents: a systematic review. Eat Weight Disord. 2017; 22: 211–229.
  520. Ebbeling C.B., Feldman H.A., Chomitz V.R., et al. A randomized trial of sugar-sweetened beverages and adolescent body weight. N Engl J Med. 2012; 367: 1407–1416.
  521. Sung-Chan P., Sung Y.W., Zhao X., et al. Family-based models for childhood-obesity intervention: a systematic review of randomized controlled trials. Obes Rev. 2013; 14: 265–278.
  522. Couturier J., Kimber M., Szatmari P. Efficacy of family-based treatment for adolescents with eating disorders: a systematic review and meta-analysis. Int J Eat Disord. 2013; 46: 3–11.
  523. US Preventative Services Task Force. Screening and behavioral counseling interventions to reduce unhealthy alcohol use in adolescents and adults: updated evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2018; 320: 1910–1928.
  524. Stockings E., Hall W.D., Lynskey M., et al. Prevention, early intervention, harm reduction, and treatment of substance use in young people. Lancet Psychiatry. 2016; 3: 280–296.
  525. Tanner-Smith E.E., Lipsey M.W. Brief alcohol interventions for adolescents and young adults: a systematic review and meta-analysis. J Subst Abuse Treat. 2015; 51: 1–18.
  526. Patton G.C., Sawyer S.M., Santelli J.S., et al. Our future: a lancet commission on adolescent health and wellbeing. Lancet. 2016; 387: 2423–2478.
  527. Zhu J., Chan Y.M. Adult consequences of self-limited delayed puberty. Pediatrics. 2017; 139: e20163177.
  528. Centers for Disease Control and Prevention’s Web-based Statistics Query and Reporting System (WISQARSTM). https://webappa.cdc.gov/sasweb/ncipc/leadcause.html. Accessed May 10, 2019.
  529. Siu A.L. Screening for depression in children and adolescents: US preventive services task force recommendation statement. Pediatrics. 2016; 137: 1–10.
  530. Practice bulletin no. 157 summary: cervical cancer screening and prevention. Obstet Gynecol. 2016; 127: 185–187.
  531. Marcell A.V., Burstein G.R. Sexual and reproductive health care services in the pediatric setting. Pediatrics. 2017; 140: 1–15.
  532. Ethier K.A., Kann L., McManus T. Sexual intercourse among high school students—29 states and United States overall, 2005–2015. MMWR Morb Mortal Wkly Rep. 2018; 66: 1393–1397.
  533. Leftwich H.K., Alves M.V. Adolescent pregnancy. Pediatr Clin North Am. 2017; 64: 381–388.
  534. Gannon-Loew K.E., Holland-Hall C., Bonny A.E. A review of expedited partner therapy for the management of sexually transmitted infections in adolescents. J Pediatr Adolesc Gynecol. 2017; 30: 341–348.
  535. National Institute for Health and Care Excellence 2017. Eating disorders: recognition and treatment (NICE clinical guideline NG69). https://www.nice.org.uk/guidance/NG69. Accessed May 10, 2019.
  536. US Preventative Services Task Force. Screening and behavioral counseling interventions to reduce unhealthy alcohol use in adolescents and adults: US Preventive Services Task Force recommendation statement. JAMA. 2018; 320: 1899–1909.
  537. Das R.R., Panigrahi I., Naik S.S. The effect of prophylactic antipyretic administration on post-vaccination adverse reactions and antibody response in children: a systematic review. PLoS ONE. 2014; 9: e106629.
  538. Bonten M.J., Huijts S.M., Bolkenbaas M., et al. Polysaccharide conjugate vaccine against pneumococcal pneumonia in adults. N Engl J Med. 2015; 372: 1114–1125.
  539. D’Addario M., Redmond S., Scott P., et al. Two-dose schedules for human papillomavirus vaccine: systematic review and meta-analysis. Vaccine. 2017; 35: 2892–2901.
  540. Haghshenas M.R., Mousavi T., Kheradmand M., et al. Efficacy of human papillomavirus L1 protein vaccines (cervarix and gardasil) in reducing the risk of cervical intraepithelial neoplasia: a meta-analysis. Int J Prev Med. 2017; 8: 44.
  541. Kraicer-Melamed H., O’Donnell S., Quach C. The effectiveness of pneumococcal polysaccharide vaccine 23 (PPV23) in the general population of 50 years of age and older: a systematic review and meta-analysis. Vaccine. 2016; 34: 1540–1550.
  542. Macartney K., Heywood A., McIntyre P. Vaccines for post-exposure prophylaxis against varicella (chickenpox) in children and adults. Cochrane Database Syst Rev. 2014; (6): CD001833.
  543. Cunningham A.L., Lal H., Kovac M., et al. Efficacy of the herpes zoster subunit vaccine in adults 70 years of age or older. N Engl J Med. 2016; 375: 1019–1032.
  544. Kim D.K., Hunter P. Recommended adult immunization schedule, United States, 2019. Ann Intern Med. 2019; 170: 182–192.
  545. Centers for Disease Control and Prevention. Advisory Committee on Immunization Practices (ACIP) recommended immunization schedule for adults aged 19 years and older—United States. 2018. http://www.cdc.gov/vaccines/schedules/downloads/adult/adult-combined-schedule.pdf; Accessed May 31, 2019.
  546. Kamiya H., Cho B.H., Messonnier M.L., et al. Impact and cost-effectiveness of a second tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine dose to prevent pertussis in the United States. Vaccine. 2016; 34: 1832–1838.
  547. Schillie S., Vellozzi C., Reingold A., et al. Prevention of hepatitis B virus infection in the United States: recommendations of the advisory committee on immunization practices. MMWR Recomm Rep. 2018; 67: 1–31.
  548. Petrosky E., Bocchini J.A., Hariri S., et al. Use of 9-valent human papillomavirus (HPV) vaccine: updated HPV vaccination recommendations of the advisory committee on immunization practices. MMWR Morb Mortal Wkly. 2015; 64: 300–304.
  549. Grohskopf L.A., Sokolow L.Z., Fry A.M., et al. Update: ACIP recommendations for the use of quadrivalent live attenuated influenza vaccine (LAIV4) — United States, 2018-19 influenza season. MMWR Morb Mortal Wkly Rep. 2018; 67: 643–645.
  550. Lu D., Qiao Y., Brown N.E., et al. Racial and ethnic disparities in influenza vaccination among adults with chronic medical conditions vary by age in the United States. PLoS ONE. 2017; 12: 1–12.
  551. Centers for Disease Control and Prevention. Seasonal influenza vaccine effectiveness, 2005–2018. https://www.cdc.gov/flu/vaccines-work/effectiveness-studies.htm. Accessed May 31, 2019.
  552. Hampton L.M., Farrell M., Ramirez-Gonzalez A, et al. Cessation of trivalent oral poliovirus vaccine and introduction of inactivated poliovirus vaccine—worldwide, 2016. MMWR Morb Mortal Wkly Rep. 2016; 65: 934–938.
  553. Centers for Disease Control and Prevention. Traveler’s health. www.cdc.gov/travel; Accessed May 31, 2019.
  554. Sowah D, Boyko R, Antle D, et al. Occupational interventions for the prevention of back pain: overview of systematic reviews. J Safety Res. 2018; 66: 39–59.
  555. Hauge CR, Rasmussen A, Piet J, et al. Mindfulness-based cognitive therapy (MBCT) for multiple chemical sensitivity (MCS): results from a randomized controlled trial with 1 year follow-up. J Psychosom Res. 2015; 79: 628–634.
  556. Talini D, Ciberti A, Bartoli D, et al. Work-related asthma in a sample of subjects with established asthma. Respir Med. 2017; 130: 85–91.
  557. Perlman DM, Maier LA. Occupational lung disease. Med Clin North Am. 2019; 103: 535–548.
  558. Clarhed UKE, Svendsen M, Schioler L, et al. Chronic rhinosinusitis related to occupational exposure — the telemark population study. J Occup Environ Med. 2018; 60: 656–660.
  559. Rajagopalan S, Al-Kindi SG, Brook RD. Air pollution and cardiovascular disease: JACC state-of-the-art review. J Am Coll Cardiol. 2018; 72: 2054–2070.
  560. Hadley MB, Baumgartner J, Vedanthan R. Developing a clinical approach to air pollution and cardiovascular health. Circulation. 2018; 137: 725–742.
  561. Vincent M, Percier P, De Prins S, et al. Investigation of inflammatory and allergic responses to common mold species: results from in vitro experiments, from a mouse model of asthma, and from a group of asthmatic patients. Indoor Air. 2017; 27: 933–945.
  562. Singh V.K., Romaine P.L., Seed T.M. Medical countermeasures for radiation exposure and related injuries: characterization of medicines, FDA-approval status and inclusion into the Strategic National Stockpile. Health Phys. 2015; 108: 607–630.
  563. Gu J., Zhu S., Li X., et al. Effect of amifostine in head and neck cancer patients treated with radiotherapy: a systematic review and meta-analysis based on randomized controlled trials. PLoS ONE. 2014; 9: 1–9.
  564. Lee M.G., Freeman A.R., Roos D.E., et al. Randomized double-blind trial of amifostine versus placebo for radiation-induced xerostomia in patients with head and neck cancer. J Med Imaging Radiat Oncol. 2019; 63: 142–150.
  565. Mazhari F., Shirazi A.S., Shabzendehdar M. Management of oral mucositis in pediatric patients receiving cancer therapy: a systematic review and meta-analysis. Pediatr Blood Cancer. 2019; 68: 1–9.
  566. Lawrie T.A., Green J.T., Beresford M., et al. Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic cancers. Cochrane Database Syst Rev. 2018; (1): CD012529.
  567. Sato A., Lyamzina Y. Diversity of concerns in recovery after a nuclear accident: a perspective from Fukushima. Int J Environ Res Public Health. 2018; 15: 1–20.
  568. Gale R.P., Armitage J.O. Are we prepared for nuclear terrorism? N Engl J Med. 2018; 378: 1246–1254.
  569. Citrin D.E. Recent developments in radiotherapy. N Engl J Med. 2017; 377: 1065–1075.
  570. Grant E.J., Brenner A., Sugiyama H., et al. Solid cancer incidence among the life span study of atomic bomb survivors: 1958-2009. Radiat Res. 2017; 187: 513–537.
  571. Kamiya K., Ozasa K., Akiba S., et al. Long-term effects of radiation exposure on health. Lancet. 2015; 386: 469–478.
  572. Dasu A., Toma-Dasu I. Models for the risk of secondary cancers from radiation therapy. Phys Med. 2017; 42: 232–238.
  573. Shore R.E. Radiation and cataract risk: impact of recent epidemiologic studies on ICRP judgments. Mutat Res. 2016; 770: 231–237.
  574. Repin M., Pampou S., Karan C., et al. RABiT-II: implementation of a high-throughput micronucleus biodosimetry assay on commercial biotech robotic systems. Radiat Res. 2017; 187: 492–498.
  575. Sher N., Ofir R. Placenta-derived adherent stromal cell therapy for hematopoietic disorders: a case study of PLX-R18. Cell Transplant. 2018; 27: 140–150.
  576. Buonanno M., Ponnaiya B., Welch D, et al. Germicidal efficacy and mammalian skin safety of 222-nm UV light. Radiat Res. 2017; 187: 483–491.
  577. Yang M., Guo W., Yang C., et al. Mobile phone use and glioma risk: a systematic review and meta-analysis. PLoS ONE. 2017; 12: 1–13.
  578. Henao-Restrepo A.M., Camacho A., Longini I.M., et al. Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola ?a Suffit!). Lancet. 2017; 389: 505–518.
  579. Regules J.A., Beigel J.H., Paolino K.M., et al. A recombinant vesicular stomatitis virus Ebola vaccine. N Engl J Med. 2017; 376: 330–341.
  580. Narayanan N., Lacy C.R., Cruz J.E., et al. Disaster preparedness: biological threats and treatment options. Pharmacotherapy. 2018; 38: 217–234.
  581. Katharios-Lanwermeyer S., Holty J.E., Person M. et al. Identifying meningitis during an anthrax mass casualty incident: systematic review of systemic anthrax since 1880. Clin Infect Dis. 2016; 62: 1537–1545.
  582. Rubinson L., Corey A., Hanfling D. Estimation of time period for effective human inhalational anthrax treatment including antitoxin therapy. PLoS Curr. 2017; 9: 1–26.
  583. Hou A.W., Morrill A.M. Obiltoxaximab: adding to the treatment arsenal for Bacillus anthracis infection. Ann Pharmacother. 2017; 51: 908–913.
  584. Adalja A.A., Toner E., Inglesby T.V. Clinical management of potential bioterrorism-related conditions. N Engl J Med. 2015; 372: 954–962.
  585. Jackson L.A., Frey S.E., El Sahly H.M., et al. Safety and immunogenicity of a modified vaccinia Ankara vaccine using three immunization schedules and two modes of delivery: a randomized clinical non-inferiority trial. Vaccine. 2017; 35: 1675–1682.
  586. Coltart C.E., Lindsey B., Ghinai I., et al. The Ebola outbreak, 2013-2016: old lessons for new epidemics. Philos Trans R Soc Lond B Biol Sci. 2017; 372: 1–24.
  587. Lamontagne F., Fowler R.A., Adhikari N.K., et al. Evidence-based guidelines for supportive care of patients with Ebola virus disease. Lancet. 2018; 391: 700–708.
  588. Davey R.T. Jr, Dodd L., Proschan M.A., et al. A randomized, controlled trial of ZMapp for Ebola virus infection. N Engl J Med. 2016; 375: 1448–1456.
  589. Centers for Disease Control and Prevention. Guidance on personal protective equipment (PPE) to be used by healthcare workers during management of patients with confirmed Ebola or persons under investigation (PUIs) for Ebola who are clinically unstable or have bleeding, vomiting, or diarrhea in U.S. hospitals, including procedures for donning and doffing PPE. https://www.cdc.gov/vhf/ebola/healthcare-us/ppe/guidance.html. 2015. Accessed on May 17, 2019.
  590. Green M.S., LeDuc J., Cohen D., et al. Confronting the threat of bioterrorism: realities, challenges, and defensive strategies. Lancet Infect Dis. 2019; 19: e2–e13.
  591. Nussbaumer-Streit B., Yeoh B., Griebler U., et al. Household interventions for preventing domestic lead exposure in children. Cochrane Database Syst Rev. 2016; 10: CD006047.
  592. Braun J.M., Hornung R., Chen A., et al. Effect of residential lead-hazard interventions on childhood blood lead concentrations and neurobehavioral outcomes: a randomized clinical trial. JAMA Pediatr. 2018; 172: 934–942.
  593. Department of Health and Human Services, Public Health Service. Agency for Toxic Substances and Disease Registry. Toxicological Profiles. http://www.atsdr.cdc.gov/toxprofiles/index.asp; Toxic Substances Portal. http://www.atsdr.cdc.gov/substances/index.asp. Accessed June 3, 2019.
  594. Rehman K., Fatima F., Waheed I., et al. Prevalence of exposure of heavy metals and their impact on health consequences. J Cell Biochem. 2018; 119: 157–184.
  595. Chowdhury R., Ramond A., O’Keeffe L.M., et al. Environmental toxic metal contaminants and risk of cardiovascular disease: systematic review and meta-analysis. BMJ. 2018; 362: 1–13.
  596. Lanphear B.P., Rauch S., Auinger P., et al. Low-level lead exposure and mortality in US adults: a population-based cohort study. Lancet Public Health. 2018; 3: e177–e184.
  597. Strain J.J., Yeates A.J., van Wijngaarden E., et al. Prenatal exposure to methyl mercury from fish consumption and polyunsaturated fatty acids: associations with child development at 20 mo of age in an observational study in the Republic of Seychelles. Am J Clin Nutr. 2015; 101: 530–537.
  598. Morris M.C., Brockman J., Schneider J.A., et al. Association of seafood consumption, brain mercury level, and APOE ?4 status with brain neuropathology in older adults. JAMA. 2016; 315: 489–497.
  599. Mantha M., Yeary E., Trent J., et al. Estimating inorganic arsenic exposure from U.S. rice and total water intakes. Environ Health Perspect. 2017; 125: 1–10.
  600. Hadrup N., Sharma A.K., Loeschner K. Toxicity of silver ions, metallic silver, and silver nanoparticle materials after in vivo dermal and mucosal surface exposure: a review. Regul Toxicol Pharmacol. 2018; 98: 257–267.
  601. Osorio-Rico L., Santamaria A., Galvan-Arzate S. Thallium toxicity: general issues, neurological symptoms, and neurotoxic mechanisms. Adv Neurobiol. 2017; 18: 345–353.
  602. Kim K.B., Kim Y.W., Lim S.K., et al. Risk assessment of zinc oxide, a cosmetic ingredient used as a UV filter of sunscreens. J Toxicol Environ Health B Crit Rev. 2017; 20: 155–182.
  603. Racette B.A., Searles Nielsen S., Criswell S.R., et al. Dose-dependent progression of parkinsonism in manganese-exposed welders. Neurology. 2017; 88: 344–351.
  604. Zaman J., Verghese A., Elder A. The value of physical examination: a new conceptual framework. South Med J. 2016; 109: 754–757.
  605. Department of Veterans Affairs. Military Health History Pocket Card for Clinicians.
  606. Spoont M.R., Williams J.W., Jr, Kehle-Forbes S., et al. Does this patient have posttraumatic stress disorder?: rational clinical examination systematic review. JAMA. 2015; 314: 501–510.
  607. Monahan M., Jowett S., Lovibond K., et al. Predicting out-of-office blood pressure in the clinic for the diagnosis of hypertension in primary care: an economic evaluation. Hypertension. 2018; 71: 250–261.
  608. Berliner D., Schneider N., Welte T., et al. The differential diagnosis of dyspnea. Dtsch Arztebl Int. 2016; 113: 834–845.
  609. Narula J., Chandrashekhar Y., Braunwald E. Time to add a fifth pillar to bedside physical examination: inspection, palpation, percussion, auscultation, and insonation. JAMA Cardiol. 2018; 3: 346–350.
  610. Bentzer P., Griesdale D.E., Boyd J., et al. Will this hemodynamically unstable patient respond to a bolus of intravenous fluids? JAMA. 2016; 316: 1298–1309.
  611. Singh Ospina N., Maraka S., Espinosa De Ycaza A.E., et al. Physical exam in asymptomatic people drivers the detection of thyroid nodules undergoing ultrasound guided fine needle aspiration biopsy. Endocrine. 2016; 54: 433–439.
  612. Oeffinger K.C., Fontham E.T., Etzioni R., et al. Breast cancer screening for women at average risk: 2015 guideline update from the American cancer society. JAMA. 2015; 314: 1599–1614.
  613. Bennis S., Hwang S Office evaluation of pelvic pain. Phys Med Rehabil Clin N Am. 2017; 28: 461–476.
  614. Guirguis-Blake J.M., Henderson J.T., Perdue L.A., et al. Screening for Gynecologic Conditions With Pelvic Examination: A Systematic Review for the U.S. Preventive Services Task Force. Evidence Synthesis No. 147. AHRQ Publication No. 15-05220-EF-1. Rockville, MD: Agency for Healthcare Research and Quality; 2017.
  615. Halpern J.A., Oromendia C., Shoag J.E., et al. Use of digital rectal examination as an adjunct to prostate specific antigen in the detection of clinically significant prostate cancer. J Urol. 2018; 199: 947–953.
  616. Narula J., Chandrashekhar Y., Braunwald E. Time to add a fifth pillar to bedside physical examination: inspection, palpation, percussion, auscultation, and insonation. JAMA Cardiol. 2018; 3: 346–350.
  617. Gabayan GZ, Gould MK, Weiss RE, et al. Emergency department vital signs and outcomes after discharge. Acad Emerg Med. 2017; 24: 846–854.
  618. Nguyen OK, Makam AN, Clark C, et al. Vital signs are still vital: instability on discharge and the risk of post-discharge adverse outcomes. J Gen Intern Med. 2017; 32: 42–48.
  619. Jayasundera R, Neilly M, Smith TO, et al. Are early warning scores useful predictors for mortality and morbidity in hospitalised acutely unwell older patients? A systematic review. J Clin Med. 2018; 7: 309.
  620. Cantillon DJ, Loy M, Burkle A, et al. Association between off-site central monitoring using standardized cardiac telemetry and clinical outcomes among non-critically ill patients. JAMA. 2016; 316: 519–524.
  621. Geneva II, Cuzzo B, Fazili T, et al. Normal body temperature: a systematic review. Open Forum Infect Dis. 2019; 6: 1–7.
  622. Oka T. Stress-induced hyperthermia and hypothermia. Handb Clin Neurol. 2018; 157: 599–621.
  623. Bentzer P, Griesdale DE, Boyd J, et al. Will this hemodynamically unstable patient respond to a bolus of intravenous fluids? JAMA. 2016; 316: 1298–1309.
  624. Hale ZE, Singhal A, Hsia RY. Causes of shortness of breath in the acute patient: a national study. Acad Emerg Med. 2018. [Epub ahead of print.].
  625. Chavalarias D, Wallach JD, Li AH, et al. Evolution of reporting P values in the biomedical literature, 1990–2015. JAMA. 2016; 315: 1141–1148.
  626. Kaji AH, Lewis RJ. Noninferiority trials: is a new treatment almost as effective as another? JAMA. 2015; 313: 2371–2372.
  627. Haukoos JS, Lewis RJ. The propensity score. JAMA. 2015; 314: 1637–1638.
  628. Chen JH, Asch SM. Machine learning and prediction in medicine — beyond the peak of inflated expectations. N Engl J Med. 2017; 376: 2507–2509.
  629. Meurer WJ, Tolles J. Logistic regression diagnostics: understanding how well a model predicts outcomes. JAMA. 2017; 317: 1068–1069.
  630. Dmitrienko A, D’Agostino RB Sr. Multiplicity considerations in clinical trials. N Engl J Med. 2018; 378: 2115–2122.
  631. Cargo M, Harris J, Pantoja T, et al. Cochrane qualitative and implementation methods group guidance series-paper 4: methods for assessing evidence on intervention implementation. J Clin Epidemiol. 2018; 97: 59–69.
  632. McGee S. Teaching evidence-based physical diagnosis: six bedside lessons. South Med J. 2016; 109: 738–742.
  633. Neumann PJ, Cohen JT. QALYs in 2018 — advantages and concerns. JAMA. 2018; 319: 2473–2474.
  634. Spatz ES, Krumholz HM, Moulton BW. Prime time for shared decision making. JAMA. 2017; 317: 1309–1310.
  635. Sanders GD, Maciejewski ML, Basu A. Overview of cost-effectiveness analysis. JAMA. 2019. [Epub ahead of print.]
  636. Alba AC, Agoritsas T, Walsh M, et al. Discrimination and calibration of clinical prediction models: users’ guides to the medical literature. JAMA. 2017; 318: 1377–1384.
  637. Thorlund K, Haggstrom J, Park JJ, et al. Key design considerations for adaptive clinical trials: a primer for clinicians. BMJ. 2018; 360: 1–9.
  638. Bhatt DL, Mehta C. Adaptive designs for clinical trials. N Engl J Med. 2016;375:65-74.
  639. Ford I, Norrie J. Pragmatic trials. N Engl J Med. 2016; 375: 454–463.
  640. Mauri L, D’Agostino RB Sr. Challenges in the design and interpretation of noninferiority trials. N Engl J Med. 2017; 377: 1357–1367.
  641. Hernan MA, Robins JM. Per-protocol analyses of pragmatic trials. N Engl J Med. 2017; 377: 1391–1398.
  642. Irony TZ. Case-control studies: using “real-world” evidence to assess association. JAMA. 2018; 320: 1027–1028.
  643. Schneider EC, Sarnak DO, Squires D, et al. Mirror, mirror 2017: international comparison reflects flaws and opportunities for better U.S. health care.
  644. Hoffmann TC, Del Mar C. Clinicians’ expectations of the benefits and harms of treatments, screening, and tests: a systematic review. JAMA Intern Med. 2017; 177: 407–419.
  645. Schmidt HG, Van Gog T, Schuit SC, et al. Do patients’ disruptive behaviours influence the accuracy of a doctor’s diagnosis? A randomised experiment. BMJ Qual Saf. 2017; 26: 19–23.
  646. Barker AL, Morello RT, Wolfe R, et al. 6-PACK programme to decrease fall injuries in acute hospitals: cluster randomised controlled trial. BMJ. 2016; 352: 1–9.
  647. Bilimoria KY, Chung JW, Hedges LV, et al. National cluster-randomized trial of duty-hour flexibility in surgical training. N Engl J Med. 2016; 374: 713–727.
  648. Makary MA, Daniel M. Medical error — the third leading cause of death in the US. BMJ. 2016; 353: 1–5.
  649. Porter ME, Larsson S, Lee TH. Standardizing patient outcomes measurement. N Engl J Med. 2016; 374: 504–506.
  650. Mendelson A, Kondo K, Damberg C, et al. The effects of pay-for-performance programs on health, health care use, and processes of care: a systematic review. Ann Intern Med. 2017; 166: 341–353.
  651. Studdert DM, Bismark MM, Mello MM, et al. Prevalence and characteristics of physicians prone to malpractice claims. N Engl J Med. 2016; 374: 354–362.
  652. Bhise V, Sittig DF, Vaghani V, et al. An electronic trigger based on care escalation to identify preventable adverse events in hospitalised patients. BMJ Qual Saf. 2018; 27: 241–246.
  653. Goodwin JS, Salameh H, Zhou J, et al. Association of hospitalist years of experience with mortality in the hospitalized Medicare population. JAMA Intern Med. 2018; 178: 196–203.
  654. Burke LG, Frakt AB, Khullar D, et al. Association between teaching status and mortality in US hospitals. JAMA. 2017; 317: 2105–2113.
  655. Burke L, Khullar D, Orav EJ, et al. Do academic medical centers disproportionately benefit the sickest patients? Health Aff (Millwood). 2018; 37: 864–872.
  656. Mao J, Goodney P, Cronenwett J, et al. Association of very low-volume practice with vascular surgery outcomes in New York. JAMA Surg. 2017; 152: 759–766.
  657. Attenello FJ, Wen T, Cen SY, et al. Incidence of “never events” among weekend admissions versus weekday admissions to US hospitals: national analysis. BMJ. 2015; 350: 1–9.
  658. Eid SM, Ponor L, Reed DA, et al. Associations between in-hospital mortality, health care utilization, and inpatient costs with the 2011 resident duty hour revision. J Grad Med Educ. 2019; 11: 146–155.
  659. Dykes PC, Rozenblum R, Dalal A, et al. Prospective evaluation of a multifaceted intervention to improve outcomes in intensive care: the promoting respect and ongoing safety through patient engagement communication and technology study. Crit Care Med. 2017; 45: e806–e813.
  660. McManus RJ, Mant J, Haque MS, et al. Effect of self-monitoring and medication self-titration on systolic blood pressure in hypertensive patients at high risk of cardiovascular disease: the TASMIN-SR randomized clinical trial. JAMA. 2014; 312: 799–808.
  661. Kastner M, Cardoso R, Lai Y, et al. Effectiveness of interventions for managing multiple high-burden chronic diseases in older adults: a systematic review and meta-analysis. CMAJ. 2018; 190: E1004–E1012.
  662. Lenferink A, Brusse-Keizer M, van der Valk PD, et al. Self-management interventions including action plans for exacerbations versus usual care in patients with chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2017; 8: CD011682.
  663. Posadzki P, Mastellos N, Ryan R, et al. Automated telephone communication systems for preventive healthcare and management of long-term conditions. Cochrane Database Syst Rev. 2016; 12: CD009921.
  664. Wagner EH, Flinter M, Hsu C, et al. Effective team-based primary care: observations from innovative practices. BMC Fam Pract. 2017; 18: 1–9.
  665. Allegrante JP, Wells MT, Peterson JC. Interventions to support behavioral self-management of chronic diseases. Annu Rev Public Health. 2019; 40: 127–146.
  666. Improving Chronic Illness Care.
  667. Torres H, Poorman E, Tadepalli U, et al. Coverage and access for Americans with chronic disease under the Affordable Care Act: a quasi-experimental study. Ann Intern Med. 2017; 166: 472–479.
  668. Kelley A.S., Morrison R.S. Palliative care for the seriously ill. N Engl J Med. 2015; 373: 747–755.
  669. Hui D., Bruera E. The Edmonton Symptom Assessment system 25 years later: past, present, and future developments. J Pain Symptom Manage. 2017; 53: 630–643.
  670. Kavalieratos D., Gelfman L.P., Tycon L.E., et al. Palliative care in heart failure: rationale, evidence, and future priorities. J Am Coll Cardiol. 2017; 70: 1919–1930.
  671. Bischoff K., O’Riordan D.L., Marks A.K., et al. Care planning for inpatients referred for palliative care consultation. JAMA Intern Med. 2018; 178: 48–54.
  672. Center to Advance Palliative Care.
  673. Tolle S.W., Back A.L., Meier D.E. Clinical decisions. End-of-life advance directive. N Engl J Med. 2015; 372: 667–670.
  674. Epstein A.S., Prigerson H.G., O’Reilly E.M., et al. Discussions of life expectancy and changes in illness understanding in patients with advanced cancer. J Clin Oncol. 2016; 34: 2398–2403.
  675. Gozalo P., Plotzke M., Mor V., et al. Changes in Medicare costs with the growth of hospice care in nursing homes. N Engl J Med. 2015; 372: 1823–1831.
  676. May P., Normand C., Cassel J.B., et al. Economics of palliative care for hospitalized adults with serious illness: a meta-analysis. JAMA Intern Med. 2018; 178: 820–829.
  677. Horvat L, Horey D, Romios P, et al. Cultural competence education for health professionals. Cochrane Database Syst Rev. 2014: CD009405.
  678. Healthy People 2020. Foundation Health Measures Archive: Disparities. Washington, DC: Office of Disease Prevention and Health Promotion (ODPHP).
  679. National Center for Health Statistics. Health, United States, 2016: With Chartbook on Long-Term Trends in Health. Hyattsville, MD; 2017.
  680. National Center for Health Statistics. Health, United States, 2015: With Special Feature on Racial and Ethnic Health Disparities. Hyattsville, MD; 2016.
  681. Chetty R, Stepner M, Abraham S, et al. The association between income and life expectancy in the United States, 2001–2014. JAMA. 2016; 315: 1750–1766.
  682. Case A, Deaton A. Rising morbidity and mortality in midlife among white non-hispanic Americans in the 21st century. Proc Natl Acad Sci USA. 2015; 112: 15078–15083.
  683. Hedegaard H, Warner M, Mini?o AM. Drug Overdose Deaths in the United States, 1999–2015. NCHS Data Brief, No 273. Hyattsville, MD: National Center for Health Statistics.; 2017.
  684. Dwyer-Lindgren L, Bertozzi-Villa A, Stubbs RW, et al. Inequalities in life expectancy among US counties, 1980 to 2014: temporal trends and key drivers. JAMA Intern Med. 2017; 177: 1003–1011.
  685. Tipirneni R, Kullgren JT, Ayanian JZ, et al. Changes in health and ability to work among Medicaid expansion enrollees: a mixed methods study. J Gen Intern Med. 2019; 34: 272–280.
  686. Think Cultural Health. National Cultural and Linguistically Appropriate Services Standards. Rockville, MD: Office of Minority Health, U.S. Department of Health and Human Services.
  687. Daniel H, Bornstein SS, Kane GC. Addressing social determinants to improve patient care and promote health equity: an American College of Physicians position paper. Ann Intern Med. 2018; 168: 577–578.
  688. Roth GA, Johnson C, Abajobir A, et al. Global, regional, and national burden of cardiovascular diseases for 10 causes, 1990 to 2015. J Am Coll Cardiol. 2017; 70: 1–25.
  689. Thomas B, Matsushita K, Abate KH, et al. Global cardiovascular and renal outcomes of reduced GFR. J Am Soc Nephrol. 2017; 28: 2167–2179.
  690. Development goals in an era of demographic change: global monitoring report 2015/2016. World Bank Group 2016.
  691. Goldman L. Three stages of health encounters over 8000 human generations and how they inform future public health. Am J Public Health. 2018; 108: 60–62.
  692. Vassy JL, Christensen KD, Schonman EF, et al. The impact of whole-genome sequencing on the primary care and outcomes of healthy adult patients: a pilot randomized trial. Ann Intern Med. 2017; 167: 159–169.
  693. June CH, O’Connor RS, Kawalekar OU, et al. CAR T cell immunotherapy for human cancer. Science. 2018; 359: 1361–1365.
  694. Ribas A, Wolchok JD. Cancer immunotherapy using checkpoint blockade. Science. 2018; 359: 1350–1355.
  695. Wraith DC. The future of immunotherapy: a 20-year perspective. Front Immunol. 2017; 8: 1–6.
  696. Kalemkerian GP, Narula N, Kennedy EB, et al. Molecular testing guideline for the selection of patients with lung cancer for treatment with targeted tyrosine kinase inhibitors: American society of clinical oncology endorsement of the college of American Pathologists/international association for the study of lung Cancer/association for molecular pathology clinical practice guideline update. J Clin Oncol. 2018; 36: 911–919.
  697. Nam JG, Park S, Hwang EJ, et al. Development and validation of deep learning–based automatic detection algorithm for malignant pulmonary nodules on chest radiographs. Radiology. 2019; 290: 218–228.
  698. Wolford BN, Willer CJ, Surakka I. Electronic health records: the next wave of complex disease genetics. Hum Mol Genet. 2018; 27: R14–R21.
  699. Bastarache L, Hughey JJ, Hebbring S, et al. Phenotype risk scores identify patients with unrecognized mendelian disease patterns. Science. 2018; 359: 1233–1239.
  700. Smith CD, Levinson WS. A commitment to high-value care education from the internal medicine community. Ann Intern Med. 2015; 162: 639–640.
  701. Sinsky C, Colligan L, Li L, et al. Allocation of physician time in ambulatory practice: a time and motion study in 4 specialties. Ann Intern Med. 2016; 165: 753–760.
  702. Hales CM, Fryar CD, Carroll MD, et al. Trends in obesity and severe obesity prevalence in US youth and adults by sex and age, 2007-2008 to 2015-2016. JAMA. 2018; 319: 1723–1725.
  703. Case A, Deaton A. Mortality and morbidity in the 21st century. Brookings Pap Econ Act. 2017; 2017: 397–476.
  704. Yeh RW, Kramer DB. Decision tools to improve personalized care in cardiovascular disease: moving the art of medicine toward science. Circulation. 2017; 135: 1097–1100.
  705. Studdert DM, Bismark MM, Mello MM, et al. Prevalence and characteristics of physicians prone to malpractice claims. N Engl J Med. 2016; 374: 354–362.
  706. Egener BE, Mason DJ, McDonald WJ, et al. The charter on professionalism for health care organizations. Acad Med. 2017; 92: 1091–1099.
  707. Kaufman EJ, Morrison CN, Branas CC, et al. State firearm laws and interstate firearm deaths from homicide and suicide in the United States: a cross-sectional analysis of data by county. JAMA Intern Med. 2018; 178: 692–700.
  708. West CP, Dyrbye LN, Shanafelt TD. Physician burnout: contributors, consequences and solutions. J Intern Med. 2018; 283: 516–529.
  709. Stacey D., L?gar? F., Lewis K., et al. Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev. 2017;4:CD001431.
  710. Haussen D.C., Doppelheuer S., Schindler K., et al. Utilization of a smartphone platform for electronic informed consent in acute stroke trials. Stroke. 2017;48:3156-3160.
  711. Fernandez Lynch H., Joffe S., Feldman E.A. Informed consent and the role of the treating physician. N Engl J Med. 2018; 378: 2433–2438.
  712. Grady C., Cummings S.R., Rowbotham M.C., et al. Informed consent. N Engl J Med. 2017; 376: 856–867.
  713. Caring Info, a program of the National Hospice and Palliative Care Organization.
  714. Scheunemann L.P., Cunningham T.V., Arnold R.M., et al. How clinicians discuss critically ill patients’ preferences and values with surrogates: an empirical analysis. Crit Care Med. 2015; 43: 757–764.
  715. Robinson E.M., Cadge W., Zollfrank A.A., et al. After the DNR: surrogates who persist in requesting cardiopulmonary resuscitation. Hastings Cent Rep. 2017; 47: 10–19.
  716. Snyder Sulmasy L., Mueller P.S. Ethics and the legalization of physician-assisted suicide: an American college of physicians position paper. Ann Intern Med. 2017; 167: 576–578.
  717. Emanuel E.J., Onwuteaka-Philipsen B.D., Urwin J.W., et al. Attitudes and practices of euthanasia and physician-assisted suicide in the United States, Canada, and Europe. JAMA. 2016; 316: 79–90.
  718. Hedberg K. New C. Oregon’s death with dignity act: 20 years of experience to inform the debate. Ann Intern Med. 2017; 167: 579–583.
  719. Preston R. Death on demand? An analysis of physician-administered euthanasia in The Netherlands. Br Med Bull. 2018; 125: 145–155.
  720. Sheehan K., Gaind K.S., Downar J. Medical assistance in dying: special issues for patients with mental illness. Curr Opin Psychiatry. 2017; 30: 26–30.
  721. Tao D.L., Boothby A., McLouth J., et al. Financial conflicts of interest among hematologist-oncologists on twitter. JAMA Intern Med. 2017; 177: 425–427.
  722. Kavalieratos D., Corbelli J., Zhang D., et al. Association between palliative care and patient and caregiver outcomes: a systematic review and meta-analysis. JAMA. 2016; 316: 2104–2114.
  723. Beernaert K., Smets T., Cohen J., et al. Improving comfort around dying in elderly people: a cluster randomised controlled trial. Lancet. 2017; 390: 125–134.
  724. Gaertner J., Siemens W., Meerpohl J.J., et al. Effect of specialist palliative care services on quality of life in adults with advanced incurable illness in hospital, hospice, or community settings: systematic review and meta-analysis. BMJ. 2017; 357: j2925.
  725. Rogers J.G., Patel C.B., Mentz R.J., et al. Palliative care in heart failure: the PAL-HF randomized, controlled clinical trial. J Am Coll Cardiol. 2017; 70: 331–341.
  726. Ferrell B.R., Temel J.S., Temin S., et al. Integration of palliative care into standard oncology care: American society of clinical oncology clinical practice guideline update. J Clin Oncol. 2017; 35: 96–112.
  727. GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the global burden of disease study 2017. Lancet. 2018; 392: 1736–1788.
  728. GBD 2015 Child Mortality Collaborators. Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980–2015: a systematic analysis for the global burden of disease study 2015. Lancet. 2016; 388: 1725–1774.
  729. Dheda K, Gumbo T, Maartens G, et al. The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis. Lancet Respir Med. 2017; 5: 291–360.
  730. GBD 2017 DALYs and HALE Collaborators. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018; 392: 1859–1922.
  731. Chockalingam A. Next major challenge in global noncommunicable diseases. Int J Non-Commun Dis. 2017; 2: 27–29.
  732. Allen L, Williams J, Townsend N, et al. Socioeconomic status and non-communicable disease behavioural risk factors in low-income and lower-middle-income countries: a systematic review. Lancet Glob Health. 2017; 5: e277–e289.
  733. GBD 2015 Tobacco Collaborators. Smoking prevalence and attributable disease burden in 195 countries and territories, 1990–2015: a systematic analysis from the global burden of disease study 2015. Lancet. 2017; 389: 1885–1906.
  734. Forouzanfar MH, Liu P, Roth GA, et al. Global burden of hypertension and systolic blood pressure of at least 110 to 115 mm hg, 1990–2015. JAMA. 2017; 317: 165–182.
  735. Mills KT, Bundy JD, Kelly TN, et al. Global disparities of hypertension prevalence and control: a systematic analysis of population-based studies from 90 countries. Circulation. 2016; 134: 441–450.
  736. Global action plan for the prevention and control of noncommunicable diseases 2013-2020. World Health Organization 2013.
  737. Sustainable development goals. Goal 3: good health and well-being. United Nations Development Programme.
  738. Deborah J. Cook, MD, MSc, Professor of Medicine, Clinical Epidemiology & Biostatistics, McMaster University Michael G. DeGroote School of Medicine, Hamilton, Ontario, Canada
  739. David S. Cooper, MD, Professor of Medicine, Division of Endocrinology and Metabolism, The Johns Hopkins University School of Medicine, Baltimore, Maryland
  740. Joseph Craft, MD, Paul B. Beeson Professor of Medicine and Professor of Immunobiology, Departments of Internal Medicine and Immunobiology, Yale University, New Haven, Connecticut
  741. Jill P. Crandall, MD, Professor of Medicine and Chief, Division of Endocrinology, Albert Einstein College of Medicine, Bronx, New York
  742. Simon L. Croft, PhD, Professor of Parasitology, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
  743. Mary K. Crow, MD, Joseph P. Routh Professor of Rheumatic Diseases in Medicine, Weill Cornell Medical College; Physician-in-Chief and Benjamin M. Rosen Chair in Immunology and Inflammation Research, Hospital for Special Surgery, New York, New York
  744. John A. Crump, MB ChB, MD, DTM&H, McKinlay Professor of Global Health, Centre for International Health, University of Otago, Dunedin, Otago; Adjunct Professor of Medicine, Pathology, and Global Health, Division of Infectious Diseases and International Health, Duke University Medical Center, Durham, North Carolina
  745. Merit Е. Cudkowicz, MD, Professor of Neurology, Harvard Medical School and Chair of Neurology, Massachusetts General Hospital, Boston, Massachusetts
  746. Mark R. Cullen, MD, Professor of Medicine, Stanford University School of Medicine, Stanford, California
  747. Charlotte Cunningham-Rundles, MD, PhD, David S Gottesman Professor of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York
  748. Inger K. Damon, MD, PhD, Director, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia
  749. Troy E. Daniels, DDS, MS, Professor Emeritus of Oral Pathology & Pathology, University of California, San Francisco, School of Medicine, San Francisco, California
  750. Gary S. Firestein, MD, Professor of Medicine, Dean, and Associate Vice Chancellor of Clinical and Translational Research, University of California, San Diego, School of Medicine, La Jolla, California
  751. Glenn I. Fishman, MD, William Goldring Professor of Medicine and Director, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York
  752. Lee A. Fleisher, MD, Robert D. Dripps Professor and Chair, Anesthesiology and Critical Care; Professor of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
  753. Paul W. Flint, MD, Professor and Chair of Otolaryngology-Head & Neck Surgery, Oregon Health & Science University, Portland, Oregon
  754. Evan L. Fogel, MD, MSc, Professor of Medicine, Indiana University School of Medicine, Indianapolis, Indiana
  755. Chris E. Forsmark, MD, Professor of Medicine, University of Florida College of Medicine, Gainesville, Florida
  756. Pierre-Edouard Fournier, MD, PhD, Professor of Medical Bacteriology-Virology and Hygiene, Faculte de Medecine, Aix-Marseille Universite and Institut Hospitalo-Universitaire Mediterranee-Infection, Marseille, France
  757. Vance G. Fowler, Jr., MD, MHS, Professor of Medicine and of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina
  758. Manuel A. Franco, MD, PhD, Professor, Instituto de Genetica Humana, Facultad de Medicina, Pontificia Universidad Javeriana, Bogota, Colombia
  759. David O. Freedman, MD, Professor Emeritus of Infectious Diseases, University of Alabama at Birmingham School of Medicine; Medical Director, Shoreland Travax, Birmingham, Alabama
  760. Martyn A. French, MB ChB, MD, Emeritus Professor in Clinical Immunology, University of Western Australia Medical School and School of Biomedical, Sciences, Faculty of Health and Medical Sciences, Perth, Australia
  761. Karen М. Freund, MD, MPH, Professor of Medicine and Vice Chair for Faculty Affairs and Quality Improvement, Tufts University School of Medicine, Boston, Massachusetts
  762. John N. Galgiani, MD, Professor of Medicine and Director, Valley Fever Center for Excellence, University of Arizona College of Medicine; Chief Medical Officer, Valley Fever Solutions, Tucson, Arizona
  763. Patrick G. Gallagher, MD, Professor of Pediatrics, Pathology and Genetics, Yale, University School of Medicine, New Haven, Connecticut
  764. Leonard Ganz, MD, Director of Cardiac Electrophysiology, Heart and Vascular, Center, Heritage Valley Health System, Beaver, Pennsylvania
  765. Hasan Garan, MD, MS, Dickinson W. Richards, Jr. Professor of Medicine, Director, Cardiac Electrophysiology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York
  766. Guadalupe Garcia-Tsao, MD, Professor of Medicine, Yale University School of Medicine, New Haven, Connecticut; Chief of Digestive Diseases, School of Medicine, VA-CT Healthcare System, West Haven, Connecticut
  767. William M. Geisler, MD, MPH, Professor of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama
  768. Tony P. George, MD, Professor of Psychiatry and Director, Division of Brain and Therapeutics, University of Toronto; Chief, Addictions Division, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
  769. Lior Gepstein, MD, PhD, Sohnis Family Professor in Medicine, Technion — Israel Institute of Technology; Director, Cardiology Department, Rambam Health Care Campus, Haifa, Israel
  770. Susan I. Gerber, MD, Chief, Respiratory Viruses Branch, Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
  771. Dale N. Gerding, MD, Professor (retired) of Medicine, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois; Research Physician, Medicine, Edward Hines Jr. VA Hospital, Hines, Illinois
  772. Morie A. Gertz, MD, Roland Seidler Jr. Professor of the Art of Medicine and Chair Emeritus, Internal Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  773. Khalil G. Ghanem, MD, PhD, Associate Professor of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
  774. Christopher J. Gill, MD, MS, Associate Professor of Global Health, Boston University School of Public Health, Boston, Massachusetts
  775. Jeffrey S. Ginsberg, MD, Professor of Medicine, McMaster University Michael G. DeGroote School of Medicine, Hamilton, Ontario, Canada
  776. Geoffrey S. Ginsburg, MD, PhD, Professor of Medicine and Pathology and Director, Duke Center for Applied Genomics & Precision Medicine, Duke University, Durham, North Carolina
  777. Marshall J. Glesby, MD, PhD, Professor of Medicine, Weill Cornell Medical College, New York, New York
  778. John W. Gnann, Jr., MD, Professor of Medicine, Medical University of South Carolina, Charleston, South Carolina
  779. Matthew R. Golden, MD, MPH, Professor of Medicine, University of Washington School of Medicine; Director, HIV/STD Program, Public Health — Seattle & King County, Seattle, Washington
  780. David L. Goldman, MD, Associate Professor of Pediatrics, Microbiology and Immunology, Childrens Hospital at Montefiore/Albert Einstein College of Medicine, Bronx, New York
  781. Lee Goldman, MD, Harold and Margaret Hatch Professor, Chief Executive, Columbia University Irving Medical Center, Dean of the Faculties of Health Sciences and Medicine, Columbia University, New York, New York
  782. Larry B. Goldstein, MD, Ruth L Works Professor and Chairman, Department of Neurology, University of Kentucky College of Medicine; Co-Director, Kentucky Neuroscience Institute, Lexington, Kentucky
  783. Richard M. Gore, MD, Professor of Radiology, University of Chicago Pritzker School of Medicine; Chief, Section of Gastrointestinal Radiology, NorthShore University HealthSystem, Evanston, Illinois
  784. Jason Gotlib, MD, MS, Professor of Medicine, Stanford University School of Medicine, Stanford Cancer Institute, Stanford, California
  785. Eduardo Gotuzzo, MD, Professor Emeritus, Alexander von Humboldt Tropical Medicine Institute, Universidad Peruana Cayetano Heredia; Principal Professor of Medicine and Tropical Diseases, National Hospital Cayetano Heredia, Lima, Peru
  786. Leslie C. Grammer, MD, Professor of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
  787. Hartmut Grasemann, MD, PhD, Professor of Pediatrics, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada
  788. M. Lindsay Grayson, MBBS, MD, MS, Professor of Medicine, University of Melbourne, Director, Infectious Diseases & Microbiology, Austin Health, Melbourne, Victoria, Australia
  789. Harry B. Greenberg, MD, Professor of Medicine and of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California
  790. Steven A. Greenberg, MD, Professor of Neurology, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts
  791. David M. Greer, MD, MA, Professor and Chair of Neurology, Boston University School of Medicine, Boston, Massachusetts
  792. Robert C. Griggs, MD, Professor of Neurology, Medicine, Pediatrics, Pathology & Laboratory Medicine, University of Rochester School of Medicine & Dentistry, Rochester, New York
  793. Lev M. Grinberg, MD, PhD, Professor and Chair, Department of Pathology, Ural State Medical University, Ekaterinburg, Russia
  794. Daniel Grossman, MD, Professor of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, School of Medicine, San Francisco, California
  795. Lisa M. Guay-Woodford, MD, Richard L. Hudson Professor of Pediatrics, George Washington University School of Medicine and Health Science and Director, Center for Translational Research, Childrens National Medical Center, Washington D.C.
  796. Roy M. Gulick, MD, MPH, Professor of Medicine, Weill Cornell Medical School; Attending Physician, NewYork-Presbyterian Hospital, New York, New York
  797. Rajesh Gupta, MD, MEd, Associate Professor of Medicine, University of Toronto; General Internist, Medicine, St. Michael’s Hospital, Toronto, Ontario, Canada
  798. Colleen Hadigan, MD, MPH, Staff Clinician, National Institutes of Health, Laboratory of Immunoregulation, NIAID, Bethesda, Maryland
  799. Melissa M. Hagman, MD, Associate Professor of Medicine, Program Director, Internal Medicine Residency-Boise, University of Washington, Boise, Idaho
  800. Klaus D. Hagspiel, MD, Professor of Radiology, Medicine (Cardiology) and Pediatrics; Chief, Division of Noninvasive Cardiovascular Imaging, Department of Radiology and Medical Imaging, University of Virginia School of Medicine, Charlottesville, Virginia
  801. H. Hunter Handsfield, MD, Professor of Medicine Emeritus, University of Washington School of Medicine, Seattle, Washington
  802. Raymond C. Harris, MD, Anne and Roscoe R. Robinson Chair and Professor of Medicine and Associate Chair, Division of Nephrology, Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee
  803. Frederick G. Hayden, MD, Stuart S. Richardson Professor Emeritus of Clinical Virology and Professor Emeritus of Medicine, Department of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia
  804. Frederick M. Hecht, MD, Professor of Medicine, University of California, San Francisco, School of Medicine, San Francisco, California
  805. Mary К. Crow, MD, Joseph Р. Routh Professor of Rheumatic Diseases in Medicine, Weill Cornell Medical College, Physician-in-Chief and Benjamin M. Rosen Chair in Immunology and Inflammation Research, Hospital for Special Surgery, New York, New York
  806. Nancy E. Davidson, MD, Professor of Medicine and Raisbeck Endowed Chair President, Seattle Cancer Care Alliance, Senior Vice President and Director, Clinical Research, Division, Fred Hutchinson Cancer Research Center Chief, Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington
  807. Jeffrey M. Drazen, MD, Distinguished Parker B. Francis Professor of Medicine, Harvard Medical School, Senior Physician, Department of Medicine, Brigham and Womens Hospital, Boston, Massachusetts
  808. Robert C. Griggs, MD, Professor of Neurology, Medicine, Pediatrics, Pathology & Laboratory Medicine, University of Rochester School of Medicine & Dentistry, Rochester, New York
  809. Donald W. Landry, MD, PhD, Samuel Bard Professor and Chair, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, Physician-in-Chief, Columbia University Irving Medical Center, New York, New York
  810. Wendy Levinson, MD, Professor of Medicine, Chair Emeritus, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
  811. Anil K. Rustgi, MD, Irving Professor of Medicine, Director, Herbert Irving Comprehensive Cancer Center, Chief, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center Cancer Service, Columbia University Vagelos College of Physicians and Surgeons, New York, New York
  812. W. Michael Scheid, MD, Bayer-Gerald L. Mandell Professor of Infectious Diseases, Professor of Medicine, Clinical Professor of Neurosurgery, David A. Harrison Distinguished Educator, University of Virginia Health System, Charlottesville, Virginia
  813. Allen M. Spiegel, MD, Dean Emeritus, Professor of Medicine, Albert Einstein College of Medicine Bronx, New York
  814. Charles S. Abrams, MD, Francis C. Wood Professor of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
  815. Ronald S. Adler, MD, PhD, Professor of Radiology, New York University School of Medicine; NYU Langone Health, New York, New York
  816. Cem Akin, MD, PhD, Professor of Medicine, Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan
  817. Allen J. Aksamit, Jr., MD, Professor of Neurology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  818. Qais Al-Awqati, MB ChB, Robert F. Loeb Professor, Medicine, and Physiology & Cellular Biophysics, Columbia University Vagelos College of Physicians & Surgeons, New York, New York
  819. Ban Mishu Alios, MD, Associate Professor of Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee
  820. Jeffrey L. Anderson, MD, Professor of Medicine, Division of Cardiovascular Medicine, University of Utah School of Medicine; Distinguished Clinical and Research Physician, Intermountain Medical Center Heart Institute, Salt Lake City, Utah
  821. Derek C. Angus, MD, MPH, Professor and Mitchell P. Fink Endowed Chair, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
  822. Gerald B. Appel, MD, Professor of Medicine and Director, Glomerular Center, Columbia University Irving Medical Center, New York, New York
  823. Frederick R. Appelbaum, MD, Professor of Medicine, University of Washington School of Medicine; Executive Senior VP and Deputy Director, Clinical Research Division, Fred Hutchinson Cancer, Research Center, Seattle, Washington
  824. James O. Armitage, MD, Professor of Internal Medicine, University of Nebraska, Medical Center College of Medicine, Omaha, Nebraska
  825. Deborah K. Armstrong, MD, Professor of Gynecology and Obstetrics, Johns Hopkins, University School of Medicine, Baltimore, Maryland
  826. M. Amin Arnaout, MD, Professor of Medicine, Chief Emeritus, Division of Nephrology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts
  827. Robert M. Arnold, MD, Distinguished Service Professor, Chief, Section of Palliative Care and Medical Ethics, University of Pittsburgh School of Medicine; Chief Medical Officer, UPMC Palliative and Supportive Institute, UPMC Health Plan, Pittsburgh, Pennsylvania
  828. David Atkins, MD, MPH, Director, Health Services Research and Development, Office of Research and Development, Dept, of Veterans Affairs (10P9H), Washington, D.C.
  829. John P. Atkinson, MD, Professor of Medicine, Division of Rheumatology, Washington University School of Medicine in St. Louis, St. Louis, Missouri
  830. John Z. Ayanian, MD, MPP, Alice Hamilton Professor of Medicine; Director, Institute for Healthcare Policy and Innovation, University of Michigan Medical School, Ann Arbor, Michigan
  831. Larry M. Baddour, MD, Professor of Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  832. Grover C. Bagby, MD, Professor of Medicine, Molecular and Medical Genetics, Oregon Health & Science University, Portland, Oregon
  833. Barbara J. Bain, MBBS, Professor in Diagnostic Haematology, Haematology, St Mary’s Hospital Campus of Imperial College London, London, United Kingdom
  834. Dean F. Bajorin, MD, Attending Physician and Member, Memorial Sloan Kettering Cancer Center; Professor of Medicine, Weill Cornell Medical College, New York, New York
  835. Robert W. Baloh, MD, Professor of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California
  836. Charles R.M. Bangham, BM BCh, Professor of Medicine, Faculty of Medicine, Imperial College London School of Medicine, London, United Kingdom
  837. Jonathan Barasch, MD, PhD, Samuel W. Lambert Professor of Medicine, Professor of Pathology and Cell Biology, Columbia University Vagelos College of Physicians & Surgeons, New York, New York
  838. Richard L. Barbano, MD, PhD, Professor of Neurology and Chief of the Movement Disorders Division, University of Rochester School of Medicine & Dentistry, Rochester, New York
  839. Bruce Barrett, MD, PhD, Professor, Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
  840. John R. Bartholomew, MD, Professor of Medicine and Section Head Vascular Medicine, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio
  841. J.D. Bartleson, MD, Professor of Neurology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  842. Mary Barton, MD, MPP, Vice President, Performance Measurement, National Committee for Quality Assurance, Washington, D.C.
  843. Robert C. Basner, MD, Professor of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York
  844. Anne R. Bass, MD, Professor of Clinical Medicine, Weill Cornell Medical College; Attending Physician, Hospital for Special Surgery, New York, New York
  845. Stephen G. Baum, MD, Professor of Medicine and of Microbiology and Immunology,, Albert Einstein College of Medicine, Bronx, New York
  846. Julie E. Bauman, MD, MPH, Professor of Medicine, University of Arizona Cancer Center, Tucson, Arizona
  847. Daniel G. Bausch, MD, MPH&TM, Director, United Kingdom Public Health Rapid Support Team, Public Health England/London School of Hygiene and Tropical Medicine, London, United Kingdom
  848. Arnold S. Bayer, MD, Distinguished Professor of Medicine, David Geffen School of Medicine at UCLA; Senior Investigator-LA Biomedical Research Institute At Harbor-UCLA, Los Angeles, California
  849. Hasan Bazari, MD, Associate Professor of Medicine, Massachusetts General, Hospital and Harvard Medical School, Boston, Massachusetts
  850. Jeffrey J. Bazarian, MD, MPH, Professor of Emergency Medicine, University of Rochester, School of Medicine & Dentistry, Rochester, New York
  851. John H. Beigel, MD, Associate Director for Clinical Research, Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland
  852. Elisabeth H. Bel, MD, PhD, Professor and Head of the Department of Respiratory Medicine, Amsterdam University Medical Center, University of Amsterdam, The Netherlands
  853. George A. Beller, MD, Emeritus Professor of Cardiology, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia
  854. Joseph R. Berger, MD, Professor of Neurology, University of Pennsylvania Perelman, School of Medicine, Philadelphia, Pennsylvania
  855. Paul D. Berk, MD, Professor of Medicine, Columbia University Vagelos College of Physicians & Surgeons, New York, New York
  856. Nancy Berliner, MD, H. Franklin Bunn Professor of Medicine; Chief, Division of Hematology, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts
  857. James L. Bernat, MD, Professor of Neurology and Medicine, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire and Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire
  858. Philip J. Bierman, MD, Professor of Internal Medicine, University of Nebraska Medical Center College of Medicine, Omaha, Nebraska
  859. Leslie G. Biesecker, MD, Chief, Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland
  860. Michael R. Bishop, MD, Professor of Medicine and Director of the Cellular Therapy Program, Section of Hematology and Oncology, University of Chicago Pritzker School of Medicine, Chicago, Illinois
  861. Joseph J. Biundo, MD, Clinical Professor of Medicine, Tulane Medical Center, New Orleans, Louisiana
  862. Joel N. Blankson, MD, PhD, Professor of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
  863. William A. Blattner, MD, Chief Executive Officer, Salt Run Global Health and Research, Saint Augustine, Florida
  864. Thomas P. Bieck, MD, Professor of Neurology, Northwestern University Feinberg School of Medicine; Professor Emeritus of Neurological Sciences, Neurosurgery, Medicine, and Anesthesiology, Rush Medical College, Chicago, Illinois
  865. Karen C. Bloch, MD, MPH, Associate Professor of Medicine (Infectious Diseases) and Health Policy, Vanderbilt University School of Medicine, Nashville, Tennessee
  866. Henk J. Blom, PhD, Professor of Biochemistry of Inherited Metabolic Disease, Department of Clinical Genetics, Center for Lysosomal and Metabolic Diseases, Erasmus MC, Rotterdam, The Netherlands
  867. Olaf A. Bodamer, MD, PhD, Park Gerald Chair of Genetics and Genomics, Department of Medicine, Boston Childrens Hospital and Harvard Medical School, Boston, Massachusetts
  868. William E. Boden, MD, Professor of Medicine, Boston University School of Medicine; Lecturer in Medicine, Harvard Medical School; Scientific Director, Clinical Trials Network, Department of Medicine, VA Boston Healthcare System, Boston, Massachusetts
  869. Guy Boivin, MD, Professor of Microbiology, Immunology and Infectiology, CHU de Quebec-Laval University, Quebec City, Quebec, Canada
  870. Jean Bolognia, MD, Professor of Dermatology, Yale University School of Medicine, New Haven, Connecticut
  871. William Bonnez, MD, Professor Emeritus of Medicine, University of Rochester School of Medicine & Dentistry, Rochester, New York
  872. Robert A. Bonomo, MD, Professor of Medicine, Case Western Reserve University School of Medicine; Chief of Medicine, Cleveland VA Hospital, Cleveland, Ohio
  873. Sarah L. Booth, PhD, Professor of Nutrition, Tufts University; Director, USDA Human Nutrition Research Center on Aging; Director, Vitamin К Laboratory, USDA Human Nutrition Research Center on Aging, Boston, Massachusetts
  874. Patrick J. Bosque, MD, Associate Professor of Neurology, University of Colorado School of Medicine; Chief, Neurology Division, Department of Medicine, Denver Health Medical Center, Denver, Colorado
  875. Lucy Breakwell, PhD, MSc, Epidemiologist, Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia Diphtheria and Other Corynebacterium Infections
  876. David J. Brenner, PhD, DSc, Higgins Professor of Radiation Biophysics, Center for Radiological Research, Columbia University Irving Medical Center, New York, New York
  877. Laurent Brochard, MD, Keenan Chair in Critical Care and Respiratory Medicine and Professor of Medicine and Interdepartmental Division Director for Critical Care, University of Toronto Faculty of Medicine; Division of Critical Care, Saint Michaels Hospital, Toronto, Ontario, Canada
  878. Itzhak Brook, MD, Professor of Pediatrics, Georgetown University School of Medicine, Washington, D.C.
  879. Enrico Brunetti, MD, Associate Professor, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences and Staff Physician, Department of Infectious and Tropical Diseases, San Matteo Hospital Foundation, University of Pavia, Pavia, Italy
  880. Amy E. Bryant, PhD, Associate Professor of Medicine, University of Washington School of Medicine, Seattle, Washington and Research Career Scientist, Infectious Diseases Section, VA Medical Center, Boise, Idaho
  881. David M. Buchner, MD, MPH, Professor Emeritus, Department of Kinesiology & Community Health, University of Illinois Urbana Champaign, Champaign, Illinois
  882. Pierre A. Buffet, MD, PhD, Professor of Cell Biology, Faculty of Medicine, Paris University and Consultant Physician, Institut Pasteur Medical Center, Paris, France
  883. David A. Bushinsky, MD, John J. Kuiper Distinguished Professor of Medicine and of Pharmacology and Physiology, University of Rochester School of Medicine & Dentistry, Rochester, New York
  884. Vivian P. Bykerk, MD, Associate Professor of Medicine, Weill Cornell Medical College; Associate Attending Physician, Hospital for Special Surgery, New York, New York
  885. John C. Byrd, MD, Distinguished University Professor, Ohio State University, Columbus, Ohio
  886. Peter A. Calabresi, MD, Professor of Neurology and Neuroscience, Director of the Richard T Johnson Division of Neuroimmunology and Neuroinfectious Diseases; Director of the Multiple Sclerosis Center, Johns Hopkins University School of Medicine, Baltimore, Maryland
  887. David P. Calfee, MD, MS, Professor of Medicine and of Health Policy & Research, Weill Cornell Medical College; Chief Hospital Epidemiologist, NewYork-Presbyterian Hospital/Weill Cornell, New York, New York
  888. Clara Camaschella, MD, Professor of Medicine, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milano, Italy
  889. Michael Camilleri, MD, Atherton and Winifred W. Bean Professor of Medicine, Pharmacology, and Physiology, Mayo Clinic College of Medicine and Science; Consultant, Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota
  890. Maria Domenica Cappellini, MD, Professor of Internal Medicine, Department of Clinical Sciences and Community Health, University of Milan; and Ca’ Granda Foundation-Policlinico Hospital, Milan, Italy
  891. Blase A. Carabello, MD, Professor of Cardiovascular Sciences and Chief, Division of Cardiology, East Carolina University Brody School of Medicine, Greenville, North Carolina
  892. Edgar M. Carvalho, MD, PhD, Professor of Medicine, Federal University of Bahia, Oswaldo Cruz Foundation (Fiocruz), Institute de Pesquisa Gongalo Moniz (IGM), Salvador-Bahia, Brazil
  893. William H. Catherine, MD, PhD, Professor and Chair-Research Division, Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, Maryland
  894. Jane A. Cauley, DrPH, Distinguished Professor of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania
  895. Naga P. Chalasani, MD, David W Crabb Professor and Director, Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana
  896. Henry F. Chambers, MD, Professor of Medicine and Director, Clinical Research Services, Clinical Translational Science Institute, University of California, San Francisco, School of Medicine, San Francisco, California
  897. Larry W. Chang, MD, MPH, Associate Professor of Medicine, Epidemiology, and International Health, Johns Hopkins University School of Medicine and Bloomberg School of Public Health, Baltimore, Maryland
  898. Lin Н. Chen, MD, Associate Professor of Medicine, Harvard Medical School, Boston, Massachusetts and Director of the Travel Medicine Center, Division of Infectious Diseases and Travel Medicine, Mount Auburn Hospital, Cambridge, Massachusetts
  899. Sharon C-A Chen, MB, PhD, Professor of Medicine, University of Sydney and Centre for Infectious Diseases and Microbiology, ICPMR and Westmead Hospital, New South Wales, Australia
  900. William P. Cheshire, Jr., MD, Professor of Neurology, Mayo Clinic College of Medicine and Science, Jacksonville, Florida
  901. Arun Chockalingam, PhD, Professor of Epidemiology, Medicine and Global Health, Dalia Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
  902. David C. Christian!, MD, Professor of Medicine, Harvard Medical School; Physician, Pulmonary and Critical Care, Massachusetts General Hospital; Elkan Blout Professor of Environmental Genetics, Environmental Health, Harvard School of Public Health, Boston, Massachusetts
  903. Edward Chu, MD, MMS, Professor and Chief, Division of Hematology-Oncology, Deputy Director, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
  904. Theodore J. Cieslak, MD, MPH, Associate Professor of Epidemiology, Co-Medical Director, Nebraska Biocontainment Unit, College of Public Health, University of Nebraska, Omaha, Nebraska
  905. George A. Cioffi, MD, Edward S. Harkness Professor and Chair, Jean and Richard Deems Professor of Ophthalmology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York
  906. Carolyn M. Clancy, MD, Clinical Associate Professor of Internal Medicine, George Washington University School of Medicine; Assistant Deputy Undersecretary for Health, Quality, Safety and Value, Veterans Administration, Washington, D.C.
  907. Heather E. Clauss, MD, Associate Professor of Medicine, Section of Infectious Diseases, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania
  908. Daniel J. Clauw, MD, Professor of Anesthesiology, Medicine (Rheumatology) and Psychiatry, Director, Chronic Pain and Fatigue Research Center, University of Michigan Medical School, Ann Arbor, Michigan
  909. David R. Clemmons, MD, Kenan Professor of Medicine, University of North Carolina School of Medicine; Attending Physician, Medicine, UNC Hospitals, Chapel Hill, North Carolina
  910. David Cohen, MD, Professor of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York
  911. Jeffrey Cohen, MD, Chief, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland
  912. Myron S. Cohen, MD, Yeargan-Bates Eminent Professor of Medicine, Microbiology and Epidemiology, Associate Vice Chancellor for Global Health; Director, Institute of Global Health and Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, North Carolina
  913. Steven P. Cohen, MD, Professor of Anesthesiology & Critical Care Medicine, Neurology and Physical Medicine & Rehabilitation and Chief, Pain Medicine Division, Johns Hopkins School of Medicine; Director of Pain Research and Professor of Anesthesiology and Physical Medicine & Rehabilitation, Walter Reed National Military Medical Center, Uniformed Services University of the Health Sciences, Baltimore, Maryland
  914. Steven L. Cohn, MD, Professor Emeritus, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida; Clinical Professor of Medicine Emeritus, SUNY Downstate, Brooklyn, New York
  915. Joseph M. Connors, MD, Emeritus Professor, BC Cancer Centre for Lymphoid Cancer and the University of British Columbia, Vancouver, British Columbia, Canada
  916. Richard Dart, MD, PhD, Professor of Emergency Medicine, University of Colorado School of Medicine and Director, Rocky Mountain Poison and Drug Center, Denver Health and Hospital Authority, Denver, Colorado
  917. Nancy E. Davidson, MD, Professor of Medicine and Raisbeck Endowed Chair; President, Seattle Cancer Care Alliance; Senior Vice President and Director, Clinical Research Division, Fred Hutchinson Cancer Research Center; Chief, Division of Medical Oncology, University of Washington School of Medicine, Seattle, Washington
  918. Lisa M. DeAngelis, MD, Lillian Rojtman Chair in Honor of Jerome В Posner, Acting Physician-in-Chief, Memorial Hospital, Chair, Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, New York
  919. Malcolm M. DeCamp, MD, Professor of Surgery and Chair, Division of Cardiothoracic Surgery, K. Craig Kent Chair in Strategic Leadership, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
  920. Carlos Del Rio, MD, Hubert Professor and Chair, Hubert Department of Global Health, Rollins School of Public Health of Emory University; Professor, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia
  921. Gabriele C. DeLuca, MD, DPhil, Associate Professor, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, Oxfordshire, United Kingdom
  922. David W. Denning, MBBS, Professor of Infectious Diseases in Global Health and Director of the National Aspergillosis Centre, University of Manchester and Wythenshawe Hospital, Manchester, United Kingdom
  923. Patricia A. Deuster, PhD, MPH, Professor and Director, Department of Military and Emergency Medicine, Director, Consortium for Health and Military Performance, Uniformed Services University, Bethesda, Maryland
  924. Robert B. Diasio, MD, William J and Charles H Mayo Professor of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  925. David J. Diemert, MD, Associate Professor, Departments of Medicine and Microbiology, Immunology and Tropical Medicine, George Washington University School of Medicine and Health Sciences, Washington, D.C.
  926. Kathleen B. Digre, MD, Professor of Neurology and Ophthalmology, University of Utah School of Medicine, Salt Lake City, Utah
  927. James. H. Doroshow, MD, Deputy Director for Clinical and Translational Research, Director, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland
  928. John M. Douglas, Jr., MD, Executive Director, Tri-County Health Department, Greenwood Village, Colorado
  929. Jeffrey M. Drazen, MD, Distinguished Parker B. Francis Professor of Medicine, Harvard Medical School and Senior Physician, Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts
  930. Dimitri Drekonja, MD, MS, Associate Professor of Medicine, University of Minnesota and Chief, Infectious Diseases Section, Minneapolis VA Health Care System, Minneapolis, Minnesota
  931. Stephen C. Dreskin, MD, PhD, Professor of Medicine and Immunology, University of Colorado School of Medicine, Aurora, Colorado
  932. W. Lawrence Drew, MD, PhD, Professor Emeritus of Laboratory Medicine and Medicine, University of California, San Francisco, School of Medicine, San Francisco, California
  933. George L. Drusano, MD, Professor of Medicine and Director, Institute for Therapeutic Innovation, University of Florida College of Medicine, Orlando, Florida
  934. Thomas D. DuBose, Jr., MD, Professor Emeritus of Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina; Visiting Professor of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia
  935. J. Stephen Dumler, MD, Professor and Chairperson, Joint Departments of Pathology, Uniformed Services University, Walter Reed National Military Medical Center, and Joint Pathology Center, Bethesda, Maryland
  936. Herbert L. DuPont, MD, Professor of Infectious Diseases, University of Texas School of Public Health, Mary W Kelsey Chair, University of Texas McGovern Medical School, Houston, Texas
  937. Madeleine Duvic, MD, Professor and Deputy Chairman, Department of Dermatology, University Texas MD Anderson Cancer Center, Houston, Texas
  938. Kathryn M. Edwards, MD, Sarah H. Sell and Cornelius Vanderbilt Chair in Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee
  939. N. Lawrence Edwards, MD, Professor and Vice Chairman, Department of Medicine, University of Florida College of Medicine; Chief, Section of Rheumatology Medicine, Malcolm Randall Veterans Administration Medical Center, Gainesville, Florida
  940. Lawrence H. Einhorn, MD, Distinguished Professor of Medicine, Indiana University, School of Medicine, Indianapolis, Indiana
  941. George M. Eliopoulos, MD, Professor of Medicine, Harvard Medical School; Physician, Beth Israel Deaconess Medical Center, Boston, Massachusetts
  942. Perry M. Elliott, MBBS, MD, Professor of Cardiovascular Medicine, Institute of Cardiovascular Science, University College London & St. Bartholomews Hospital, London, United Kingdom
  943. Jerrold J. Ellner, MD, Professor of Medicine, Rutgers-New Jersey Medical School; Director of Research Innovations, Center for Emerging Pathogens, Newark, New Jersey
  944. Ezekiel J. Emanuel, MD, PhD, Vice Provost for Global Initiatives, Office of the Provost; Chair, Department of Medical Ethics and Health Policy, University of Pennsylvania, Philadelphia, Pennsylvania
  945. Joel D. Ernst, MD, Professor and Chief, Division of Experimental Medicine, University of California, San Francisco, School of Medicine, San Francisco, California
  946. Gregory T. Everson, MD, Professor of Medicine, University of Colorado Denver; Director of Hepatology, Hepatology and Transplant Center, University of Colorado Hospital, Aurora, Colorado
  947. Amelia Evoli, MD, Associate Professor of Neurology, Institute of Neurology, Catholic University, Roma, Italy
  948. Matthew E. Falagas, MD, MSc, DSc, Director, Alfa Institute of Biomedical Sciences and Chief, Department of Medicine, Henry Dunant Hospital Center, Athens, Greece; Adjunct Associate Professor of Medicine, Tufts University School of Medicine, Boston, Massachusetts
  949. Gary W. Falk, MD, MS, Professor of Medicine, University of Pennsylvania Perelman, School of Medicine, Philadelphia, Pennsylvania
  950. James C. Fang, MD, Professor of Medicine, University of Utah School of Medicine; Executive Director, Cardiovascular Service Line, University of Utah Health Sciences, Salt Lake City, Utah
  951. Gene Feder, MBBS, MD, Professor, Centre for Academic Primary Care, Population Health Sciences, Bristol Medical School, University of David J. Feller-Kopman, MD, Professor of Medicine, Anesthesiology, Otolaryngology-Head & Neck Surgery and Director, Bronchoscopy & Interventional Pulmonology, Johns Hopkins University School of Medicine, Baltimore, Maryland
  952. Thomas McDonald File, Jr., MD, MSc, Professor and Chair, Infectious Disease Section, Northeast Ohio Medical University, Rootstown, Ohio; Chair, Infectious Disease Division, Summa Health, Akron, Ohio
  953. Douglas C. Heimburger, MD, MS, Professor of Medicine, Vanderbilt University School of Medicine; Associate Director for Education & Training, Vanderbilt Institute for Global Health, Vanderbilt University, Nashville, Tennessee
  954. Donald D. Hensrud, MD, MPH, Associate Professor of Preventive Medicine and Nutrition, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  955. Erik L. Hewlett, MD, Professor of Medicine, Microbiology, Immunology and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia
  956. Richard J. Hift, MMed(Med), PhD, Professor of Medicine, University of KwaZulu-Natal, Durban, KwaZulu-Natal, South Africa
  957. David R. Hill, MD, DTM&H, Professor of Medical Sciences, Director, Global Public Health, Quinnipiac University Frank H. Netter MD School of Medicine, Hamden, Connecticut
  958. Nicholas S. Hill, MD, Professor of Medicine, Tufts University School of Medicine; Chief, Division of Pulmonary, Critical Care and Sleep Medicine, Tufts Medical Center, Boston, Massachusetts
  959. Christopher D. Hillyer, MD, President and Chief Executive Officer, New York Blood Center; Professor of Medicine, Weill Cornell Medical College, New York, New York
  960. Brian D. Hoit, MD, Professor of Medicine, Physiology and Biophysics, Case Western Reserve University School of Medicine; Director of Echocardiography, Harrington Heart & Vascular Center, University Hospital Cleveland Medical Center, Cleveland, Ohio
  961. Steven M. Holland, MD, Director, Division of Intramural Research, Chief, Immunopathogenesis Section, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland
  962. Steven M. Hollenberg, MD, Professor of Medicine, Cooper Medical School of Rowan University; Director, Coronary Care Unit, Cooper University Hospital, Camden, New Jersey
  963. Edward W. Hook, III, MD, Professor of Medicine and Director, Division of Infectious Diseases, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama
  964. Jo Howard, MB BChir, Consultant Haematologist and Lead Clinician, Haematology, Guy’s and St Thomas’ National Health Service Foundation Trust; Honorary Reader, King’s College London, London, United Kingdom
  965. David J. Hunter, MBBS, MPH, ScD, Richard Doll Professor of Epidemiology and Medicine, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
  966. Khalid Hussain, MB ChB, MD, MSc, Professor of Pediatrics, Weill Cornell Medicine-Qatar; Division Chief-Endocrinology, Vice Chair for Research, Program Director-Research, Sidra Medicine, OPC, Doha, Qatar
  967. Michael C. lannuzzi, MD, MBA, Professor and Chairman, Department of Internal Medicine, Northwell-Staten Island University Hospital and Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York
  968. Robert D. Inman, MD, Professor of Medicine and Immunology, University of Toronto and Kremil Research Institute, University Health Network, Toronto, Ontario, Canada
  969. Sharon K. Inouye, MD, MPH, Professor of Medicine, Harvard Medical School; Director, Aging Brain Center, Marcus Institute for Aging Research-Hebrew SeniorLife, Boston, Massachusetts
  970. Michael G. Ison, MD, MS, Professor of Medicine (Infectious Diseases) and Surgery (Organ Transplantation), Northwestern University Feinberg School of Medicine, Chicago, Illinois
  971. Karen R. Jacobson, MD, MPH, Assistant Professor of Medicine, Medical Director, Boston Tuberculosis Clinic, Boston University School of Medicine, Boston, Massachusetts
  972. Michael R. Jaff, DO, Professor of Medicine, Harvard Medical School, Boston, Massachusetts; President, Newton-Wellesley Hospital, Newton, Massachusetts
  973. Joanna C. Jen, MD, PhD, Professor of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California
  974. Dennis M. Jensen, MD, Professor of Medicine, David Geffen School of Medicine at UCLA; Staff Physician, Medicine-GI, VA Greater Los Angeles Healthcare System; Director, Human Studies Core & GI Hemostasis Research Unit, CURE Digestive Diseases Research Center, Los Angeles, California
  975. Michael D. Jensen, MD, Professor of Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  976. Robert T. Jensen, MD, Chief, Cell Biology Section, Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
  977. Alain Joffe, MD, MPH, Retired. Most recently, Associate Professor of Pediatrics, Johns Hopkins University School of Medicine and Director, Student Health and Wellness Center, Johns Hopkins University, Baltimore, Maryland
  978. Stuart Johnson, MD, Professor of Medicine/Infectious Disease, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois; Physician Researcher, Research Service, Hines VA Hospital, Hines, Illinois
  979. Robin L Jones, MD, BSc, MB, Consultant Medical Oncologist, Royal Marsden Hospital and Institute of Cancer Research, London, United Kingdom
  980. Sian Jones, MD, Associate Professor of Clinical Medicine, Weill Cornell, Medical College, New York, New York
  981. Jacqueline Jonklaas, MD, PhD, Professor of Medicine, Georgetown University School of Medicine, Washington, D.C.
  982. Richard C. Jordan, DDS, PhD, Professor of Pathology, Oral Pathology & Radiation Oncology, University of California, San Francisco, School of Medicine, San Francisco, California
  983. Charles J. Kahi, MD, MS, Professor of Clinical Medicine, Indiana University School of Medicine; GI Section Chief, Richard L. Roudebush VAMC, Indianapolis, Indiana
  984. Moses R. Kamya, MB ChB, MMed, MPH, PhD, Professor of Medicine, Makerere University School of Medicine, Kampala, Uganda
  985. Louise W. Kao, MD, Associate Professor of Clinical Emergency Medicine and Director, Medical Toxicology Fellowship Program, Indiana University School of Medicine, Indianapolis, Indiana
  986. Steven A. Kaplan, MD, Professor of Urology, Icahn School of Medicine at Mount Sinai; Director, Men’s Health Program, Mount Sinai Health System, New York, New York
  987. Daniel L. Kastner, MD, PhD, Scientific Director, Division of Intramural Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland
  988. David A. Katzka, MD, Professor of Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  989. Debra K. Katzman, MD, Professor of Pediatrics, The Hospital for Sick Children and University of Toronto; Senior Associate Scientist, Research Institute; Director, Health Science Research, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
  990. Carol A. Kauffman, MD, Professor of Internal Medicine and Chief, Infectious Diseases, Veterans Affairs Ann Arbor Healthcare System, University of Michigan Medical School, Ann Arbor, Michigan
  991. Kenneth Kaushansky, MD, Professor of Medicine, Senior Vice President for Health Sciences, and Dean, Stony Brook University School of Medicine, Stony Brook, New York
  992. Keith S. Kaye, MD, MPH, Professor of Medicine, University of Michigan Medical School, Ann Arbor, Michigan
  993. Armand Keating, MD, Professor of Medicine and Professor, Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Canada
  994. Robin K. Kelley, MD, Associate Professor of Clinical Medicine, University of California, San Francisco, School of Medicine, San Francisco, California
  995. Morton J. Kern, MD, Professor of Medicine and Associate Chief of Cardiology, University of California, Irvine, Orange, California; Chief of Medicine, Long Beach Veterans Health Care System, Long Beach, California
  996. Gerald T. Keusch, MD, Professor of Medicine, Boston University School of Medicine, Boston, Massachusetts
  997. Fadlo R. Khuri, MD, President and Professor of Hematology and Medical Oncology, American University of Beirut; Adjunct Professor of Medicine, Pharmacology and Otolaryngology, Emory University School of Medicine, Atlanta, Georgia
  998. Louis V. Kirchhoff, MD, MPH, Professor of Internal Medicine (Infectious Diseases), Psychiatry, and Epidemiology, University of Iowa Carver College of Medicine and College of Public Health, Iowa City, Iowa
  999. Ajay J. Kirtane, MD, Associate Professor of Medicine, Columbia University Vagelos College of Physicians and Surgeons; Chief Academic Officer, Center for Interventional Vascular Therapy; Director, Columbia University Irving Medical Center Cardiac Catheterization Laboratories, New York, New York
  1000. Amy D. Klion, MD, Senior Clinical Investigator, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland
  1001. David S. Knopman, MD, Professor of Neurology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  1002. Christine J. Ko, MD, Professor of Dermatology and Pathology, Yale University School of Medicine, New Haven, Connecticut
  1003. Dimitrios P. Kontoyiannis, MD, ScD, Texas 4000 Distinguished Endowed Professor For Cancer Research, Deputy Head, Division of Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas
  1004. Barbara S. Koppel, MD, Chief of Neurology, Metropolitan Hospital, New York, New York and Professor of Clinical Neurology, New York Medical College, Valhalla, New York
  1005. Kevin M. Korenblat, MD, Professor of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri
  1006. Bruce R. Korf, MD, PhD, Professor of Genetics, University of Alabama at Birmingham and Chief Genomics Officer, UAB Medicine, Birmingham, Alabama
  1007. Mark G. Kortepeter, MD, MPH, Professor of Epidemiology, College of Public Health, University of Nebraska, Omaha, Nebraska; Adjunct Professor of Preventive Medicine and Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland
  1008. Shyamasundaran Kottilil, MD, PhD, Professor of Medicine and Associate Chief of Infectious Diseases at the Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland
  1009. Joseph A. Kovacs, MD, Senior Investigator, Critical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, Maryland
  1010. Thomas O. Kovacs, MD, Professor of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California
  1011. Kris V. Kowdley, MD, Director, Liver Care Network and Organ Care Research, Swedish Medical Center; Clinical Professor of Medicine, Washington State University, Elson S. Floyd College of Medicine, Seattle, Washington
  1012. Monica Kraft, MD, Robert and Irene Flinn Professor and Chair, Department of Medicine, Deputy Director, Asthma and Airway Disease Research Center, University of Arizona Health Sciences, Tucson, Arizona
  1013. Christopher M. Kramer, MD, Ruth C. Heede Professor of Cardiology and Professor of Radiology, University of Virginia School of Medicine, Charlottesville, Virginia
  1014. Donna M. Krasnewich, MD, PhD, Program Director, NIGMS, National Institutes of Health, Bethesda, Maryland
  1015. Alexander Kratz, MD, PhD, MPH, Professor of Clinical Pathology and Cell Biology, Columbia University Vagelos College of Physicians and Surgeons; Director, Automated Core Laboratory and Point of Care Testing Service, Columbia University Irving Medical Center and NewYork-Presbyterian Hospital, New York, New York
  1016. Virginia Byers Kraus, MD, PhD, Professor of Medicine, Adjunct Professor of Pathology and Orthopaedic Surgery, Duke University School of Medicine, Duke Molecular Physiology Institute, Durham, North Carolina
  1017. William E. Kraus, MD, Richard and Pat Johnson Distinguished University Professor, Duke University School of Medicine, Durham, North Carolina
  1018. Peter J. Krause, MD, Senior Research Scientist, Yale University School of Public Health, Yale University School of Medicine, New Haven, Connecticut
  1019. Daniela Kroshinsky, MD, MPH, Associate Professor of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
  1020. John F. Kuemmerle, MD, Charles M. Caravati Professor of Medicine, Chair, Division of Gastroenterology, Hepatology and Nutrition, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia
  1021. Ernst J. Kuipers, MD, PhD, Professor of Medicine, Erasmus MC University Medical Center, Rotterdam, Netherlands
  1022. Daniel Laheru, MD, Ian T. MacMillan Professorship in Clinical Pancreatic Research, Johns Hopkins University School of Medicine, Baltimore, Maryland
  1023. Donald W. Landry, MD, PhD, Samuel Bard Professor and Chair, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons and Physician-in-Chief, Columbia University Irving Medical Center, New York, New York
  1024. Anthony E. Lang, MD, Jack Clark Chair in Parkinson’s Disease Research and Director, Division of Neurology, University of Toronto; Director, Morton and Gloria Shulman Movement Disorders Clinic and Edmond J. Safra Program in Parkinsons Disease, University Health Network, Toronto Western Hospital, Toronto, Ontario, Canada
  1025. Richard A. Lange, MD, MBA, Rick and Ginger Francis Endowed Professor and President, Texas Tech University Health Sciences Center, El Paso; Dean, Paul L. Foster School of Medicine, El Paso, Texas
  1026. Frank A. Lederle, MD, Formerly Professor of Medicine, University of Minnesota School of Medicine; Director of the Minneapolis Veterans Administration Center for Epidemiological and Clinical Research, Minneapolis, Minnesota
  1027. William M. Lee, MD, Meredith Mosle Chair in Liver Disease and Professor of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas
  1028. James E. Leggett, MD, Department of Medical Education, Providence Portland Medical Center; Associate Professor of Medicine Emeritus, Division of Infectious Diseases, Oregon Health & Science University, Portland, Oregon
  1029. Glenn N. Levine, MD, Professor of Medicine, Baylor College of Medicine; Director, Cardiac Care Unit, Michael E. DeBakey VA Medical Center, Houston, Texas
  1030. Marc S. Levine, MD, Emeritus Professor of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
  1031. Stephanie M. Levine, MD, Professor of Medicine, University of Texas Health San Antonio, San Antonio, Texas
  1032. Gary R. Lichtenstein, MD, Professor of Medicine, University of Pennsylvania Perelman School of Medicine; Director, Center for Inflammatory Bowel Disease, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
  1033. Jeffrey M. Liebmann, MD, Shirlee and Bernard Brown Professor and Vice Chair, Department of Ophthalmology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York
  1034. Henry W. Lim, MD, Chairman and C.S. Livingood Chair Emeritus of Dermatology, Henry Ford Hospital; Senior Vice President for Academic Affairs, Henry Ford Health System, Detroit, Michigan
  1035. Aldo A.M. Lima, MD, PhD, Professor, Institute of Biomedicine, Federal University of Ceara, Fortaleza, Ceara, Brazil
  1036. Geoffrey S.F. Ling, MD, PhD, Professor of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland
  1037. Mark S. Link, MD, Professor of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas
  1038. Donald M. Lloyd-Jones, MD, ScM, Chair and Eileen M. Foell Professor of Preventive Medicine, Senior Associate Dean for Clinical & Translational Research, Northwestern University Feinberg School of Medicine, Chicago, Illinois
  1039. Bennett Lorber, MD, DSc, Thomas M. Durant Professor of Medicine and Professor of Microbiology and Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania
  1040. Arnold Louie, MD, Professor of Medicine, Molecular Genetics and Microbiology and Associate Director, Institute for Therapeutic Innovation, University of Florida College of Medicine, Orlando, Florida
  1041. Daniel R. Lucey, MD, MPH, Adjunct Professor, Department of Medicine/Infectious Diseases, Georgetown University Medical Center, Washington, D.C.
  1042. Jeffrey M. Lyness, MD, Professor of Psychiatry & Neurology and Senior Associate Dean for Academic Affairs, University of Rochester School of Medicine & Dentistry, Rochester, New York
  1043. C. Ronald MacKenzie, MD, C. Ronald MacKenzie Chair in Ethics and Medicine, Hospital for Special Surgery; Professor of Clinical Medicine and Medical Ethics, Weill Cornell Medical College, New York, New York
  1044. Harriet L. MacMillan, CM, MD, MSc, Chedoke Health Chair in Child Psychiatry and Professor of Psychiatry & Behavioural Neurosciences and of Pediatrics, Offbrd Centre for Child Studies, McMaster University Michael G. DeGroote School of Medicine, Hamilton, Ontario, Canada
  1045. Robert D. Madoff, MD, Professor of Surgery, University of Minnesota, Minneapolis, Minnesota
  1046. Frank Maldarelli, MD, PhD, Head, Clinical Retrovirology Section, HIV Dynamics and Replication Program, NCI-Frederick, Frederick, Maryland
  1047. Atul Malhotra, MD, Kenneth M. Moser Professor of Medicine, Chief of Pulmonary and Critical Care Medicine, Director of Sleep Medicine, University of California, San Diego, School of Medicine, La Jolla, California
  1048. Mark J. Manary, MD, Helene B. Roberson Professor of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, Missouri; Senior Lecturer, Department of Community Health, University of Malawi College of Medicine, Blantyre, Malawi
  1049. Peter Manu, MD, Professor of Medicine and Psychiatry, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York; Director of Medical Services, South Oaks Hospital, Amityville, New York
  1050. Luis A. Marcos, MD, MPH, Associate Professor of Clinical Medicine, School of Medicine, Stony Brook University, Stony Brook, New York
  1051. Ariane J. Marelli, MD, MPH, Professor of Medicine and Director, McGill Adult Unit for Congenital Heart Disease, McGill University Health Centre, Montreal, Quebec, Canada
  1052. Xavier Mariette, MD, PhD, Professor of Rheumatology, Universite Paris-Sud, AP-HP, Le Kremlin Bicetre, France
  1053. Andrew R. Marks, MD, Wu Professor and Chair, Department of Physiology and Cellular Biophysics, Director, Helen and Clyde Wu Center for Molecular Cardiology, Columbia University Vagelos College of Physicians & Surgeons, New York, New York
  1054. Kieren A. Marr, MD, Professor of Medicine and Oncology and Director, Transplant and Oncology Infectious Diseases, John Hopkins University School of Medicine, Baltimore, Maryland
  1055. Thomas J. Marrie, MD, Professor of Medicine and Dean Emeritus, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
  1056. Paul Martin, MD, Professor of Medicine and Chief, Division of Gastroenterology and Hepatology, University of Miami Miller School of Medicine, Miami, Florida
  1057. Fernando J. Martinez, MD, MS, Bruce Webster Professor of Internal Medicine and Chief, Division of Pulmonary and Critical Care Medicine, Weill Cornell Medical College, New York, New York
  1058. Joel B. Mason, MD, Professor of Medicine and Nutrition, Tufts University School of Medicine; Director, Vitamins & Carcinogenesis Laboratory, U.S.D.A. Human Nutrition Research Center at Tufts University, Boston, Massachusetts
  1059. Henry Masur, MD, Chief, Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland
  1060. Amy J. Mathers, MD, Associate Professor of Medicine and Pathology, Associate Director of Clinical Microbiology, Medical Director Antimicrobial Stewardship, University of Virginia School of Medicine, Charlottesville, Virginia
  1061. Eric L. Matteson, MD, MPH, Professor of Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  1062. Michael A. Matthay, MD, Professor of Medicine and Anesthesia, University of California, San Francisco, San Francisco, California
  1063. Emeran A. Mayer, MD, Professor of Medicine and Psychiatry, Executive Director G. Oppenheimer Center for Neurobiology of Stress and Resilience, David Geffen School of Medicine at UCLA, Los Angeles, California
  1064. Stephan A. Mayer, MD, William T. Gossett Endowed Chair of Neurology, Henry Ford Health System, Professor of Neurology, Wayne State University School of Medicine, Detroit, Michigan
  1065. F. Dennis McCool, MD, Professor of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island; Memorial Hospital of Rhode Island, Pawtucket, Rhode Island
  1066. lain Mclnnes, PhD, Professor of Experimental Medicine and Director, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom
  1067. William J. McKenna, MD, Emeritus Professor of Cardiology, Institute of Cardiovascular Science, University College London, London, United Kingdom
  1068. Vallerie McLaughlin, MD, Professor of Medicine, University of Michigan Medical School; Director, Pulmonary Hypertension Program, Ann Arbor, Michigan
  1069. John J.V. McMurray, BSc, MB ChB, MD, Professor of Medical Cardiology, British Heart Foundation Cardiovascular Research Centre, University of Glasgow; Honorary Consultant Cardiologist, Queen Elizabeth University Hospital Glasgow, Glasgow, Scotland, United Kingdom
  1070. Kenneth R. McQuaid, MD, Professor of Clinical Medicine and Vice-Chair, Department of Medicine, University of California, San Francisco, School of Medicine; Chief of Gastroenterology and of the Medical Service, San Francisco Veterans, Affairs Medical Center, San Francisco, California
  1071. Paul S. Mead, MD, MPH, Chief, Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado
  1072. Robert T. Means, Jr., MD, Professor of Internal Medicine, East Tennessee State University James H. Quillen College of Medicine, Johnson City, Tennessee
  1073. Graeme Meintjes, MB ChB, MPH, PhD, Professor of Medicine, University of Cape Town, Cape Town, South Africa
  1074. Genevieve B. Melton-Meaux, MD, PhD, Professor of Surgery, University of Minnesota Medical School, Minneapolis, Minnesota
  1075. Samuel T. Merrick, MD, Professor of Clinical Medicine, Weill Cornell Medical, College, New York, New York
  1076. Marc Michel, MD, Professor and Head of the Unit of Internal Medicine, Henri Mondor University Hospital, Assistance Publique Hopitaux de Paris, Universite Paris-Est Creteil, Creteil, France
  1077. Jonathan W. Mink, MD, PhD, Professor of Neurology, University of Rochester School of Medicine & Dentistry, Rochester, New York
  1078. William Е. Mitch, MD, Professor of Medicine, Baylor College of Medicine, Houston, Texas
  1079. Bruce A. Molitoris, MD, Distinguished Professor of Medicine, Indiana University School of Medicine, Indianapolis, Indiana
  1080. Jose G. Montoya, MD, Professor of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California; Director, Palo Alto Medical Foundation Toxoplasma Serology Laboratory, National Reference Center for the Study and Diagnosis of Toxoplasmosis, Palo Alto, California
  1081. Ernest Moy, MD, MPH, Executive Director, Office of Health Equity, Veterans Health Administration, Washington, D.C.
  1082. Debabrata Mukherjee, MD, MS, Professor and Chairman, Department of Internal Medicine, Chief, Cardiovascular Medicine, Texas Tech University Health Sciences Center, El Paso, Texas
  1083. Andrew H. Murr, MD, Professor and Chairman, Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, School of Medicine, San Francisco, California
  1084. Daniel M. Musher, MD, Distinguished Service Professor of Medicine and Professor of Molecular Virology and Microbiology, Baylor College of Medicine; Staff Physician, Infectious Disease Section, Michael E. DeBakey VA Medical Center, Houston, Texas
  1085. Robert J. Myerburg, MD, Professor of Medicine and Physiology, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida
  1086. Kari C. Nadeau, MD, PhD, Naddisy Family Foundation Professor of Allergy and Director, Sean N. Parker Center for Allergy and Asthma Research at Stanford University, Stanford, California
  1087. Stanley J. Naides, MD, President, Stanley J. Naides, M.D., P.C., Dana Point, California
  1088. Theodore E. Nash, MD, Principal Investigator, Clinical Parasitology Section, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland
  1089. Avindra Nath, MD, Chief, Section of Infections of the Nervous System, National Institutes of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, Maryland
  1090. Genevieve Neal-Perry, MD, PhD, Professor of Obstetrics and Gynecology and Director of the Reproductive Endocrinology and Infertility Center, University of Washington School of Medicine, Seattle, Washington
  1091. Anne T. Neff, MD, Professor of Medicine, Hematology/Medical Oncology, Cleveland Clinic Lerner College of Medicine; Staff Physician, Cleveland Clinic Foundation, Cleveland, Ohio
  1092. Eric G. Neilson, MD, Vice President for Medical Affairs and Lewis Landsberg Dean and Professor of Medicine and of Cell and Developmental Biology, Northwestern University Feinberg School of Medicine, Chicago, Illinois
  1093. Christina A. Nelson, MD, MPH, Medical Officer, Bacterial Diseases Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado
  1094. Lewis S. Nelson, MD, Professor and Chair, Department of Emergency Medicine; Director, Division of Medical Toxicology, Rutgers New Jersey Medical School, Newark, New Jersey
  1095. Eric J. Nestler, MD, PhD, Nash Family Professor of Neuroscience, Director, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York
  1096. Anne B. Newman, MD, MPH, Distinguished Professor and Chair, Department of Epidemiology, Katherine M. Detre Endowed Chair of Population Health Sciences; Director, Center for Aging and Population Health, Professor of Medicine, and Clinical and Translational Science Graduate School of Public Health, University of Pittsburgh; Clinical Director, Aging Institute of UPMC and Pitt, Pittsburgh, Pennsylvania
  1097. Lindsay E. Nicolle, MD, Professor Emeritus, Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
  1098. Lynnette K. Nieman, MD, Senior Investigator, Diabetes, Endocrinology and Obesity Branch, NIDDK/NIH, Bethesda, Maryland
  1099. Gaetane Nocturne, MD, PhD, Associate Professor of Rheumatology, Universite Paris-Sud, AP-HP, Le Kremlin Bicetre, France
  1100. Christopher M. O'Connor, MD, Adjunct Professor of Medicine, Duke University School of Medicine, Durham, North Carolina; CEO, Inova Heart and Vascular Institute, Fairfax, Virginia
  1101. Francis G. O'Connor, MD, MPH, Professor and Medical Director, Consortium for Health and Military Performance, Uniformed Services University of the Health Sciences, Bethesda, Maryland
  1102. Patrick G. O'Connor, MD, MPH, Dan Adams and Amanda Adams Professor and Chief, General Internal Medicine, Yale University School of Medicine, New Haven, Connecticut
  1103. James R. O'Dell, MD, Bruce Professor and Vice Chair of Internal Medicine, University of Nebraska Medical Center College of Medicine; Chief of Rheumatology, Medicine, Omaha VA, Omaha, Nebraska
  1104. Anne E. O'Donnell, MD, The Nehemiah and Naomi Cohen Chair in Pulmonary Disease Research, Chief, Division of Pulmonary, Critical Care and Sleep Medicine, Georgetown University Medical Center, Washington, D.C.
  1105. Jae К. Oh, MD, Professor of Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota; Director, Heart Vascular Stroke Institute, Samsung Medical Center, Seoul, Gangnam, South Korea
  1106. Pablo C. Okhuysen, MD, Professor of Infectious Diseases, Infection Control and Employee Health, University of Texas MD Anderson Cancer Center; Adjunct Professor of Infectious Diseases, Baylor College of Medicine; Adjunct Professor of Epidemiology, Human Genetics and Environmental Health, University of Texas School of Public Health; Adjunct Professor of Infectious Diseases, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, Texas
  1107. Michael S. Okun, MD, Professor and Chair of Neurology, Fixel Institute for Neurological Diseases, University of Florida College of Medicine, Gainesville, Florida
  1108. Jeffrey E. Olgin, MD, Gallo-Chatterjee Distinguished Professor and Chief of Cardiology, University of California, San Francisco, School of Medicine, San Francisco, California
  1109. Nancy J. Olsen, MD, Professor of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania
  1110. Walter A. Orenstein, MD, DSc, Professor of Medicine, Pediatrics, Epidemiology & Global Health, Emory University School of Medicine; Associate Director, Emory Vaccine Center, Atlanta, Georgia
  1111. John J. O'Shea, MD, Scientific Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland
  1112. Douglas R. Osmon, MD, Professor of Medicine, Mayo Clinic College of Medicine and Science; Consultant, Division Infectious Disease, Mayo Clinic, Rochester, Minnesota
  1113. Catherine M. Otto, MD, J. Ward Kennedy-Hamilton Endowed Chair in Cardiology and Professor of Medicine, University of Washington School of Medicine; Director, Heart Valve Clinic, Associate Director, Echocardiography, University of Washington Medical Center, Seattle, Washington
  1114. Martin G. Ottolini, MD, Professor of Pediatrics and Director, Capstone Student Research Program, Uniformed Services University of the Health Sciences; Consultant, Pediatric Infectious Diseases, Pediatrics, Walter Reed National Military Medical Center, Bethesda, Maryland
  1115. Peter G. Pappas, MD, Professor of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama
  1116. Ben Ho Park, MD, PhD, The Donna S. Hall Professor of Medicine, Vanderbilt University School of Medicine; Со-Leader Breast Cancer Research; Director of Precision Oncology; Associate Director for Translational Research, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee
  1117. Pankaj Jay Pasricha, MD, Professor of Medicine and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland
  1118. Manisha Patel, MD, MS, Measles, Mumps, Rubella, Herpesvirus, and Domestic Polio Epidemiology Team Lead, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
  1119. Robin Patel, MD, Elizabeth P. and Robert E. Allen Professor of Individualized Medicine and Professor of Medicine and of Microbiology; Chair, Division of Clinical Microbiology; Consultant, Divisions of Clinical Microbiology and Infectious Diseases; Director, Infectious Diseases Research Laboratory, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  1120. David L. Paterson, MBBS, PhD, Professor of Medicine and Director, Centre for Clinical Research, University of Queensland, Herston, Queensland; Consultant Infectious Diseases Physician, Department of Infectious Diseases, Royal Brisbane and Women’s Hospital, Brisbane, Australia
  1121. Jean-Michel Pawlotsky, MD, PhD, Professor, Department of Virology, Henri Mondor University Hospital, Creteil, France
  1122. Thomas H. Payne, MD, Professor of Medicine, University of Washington School of Medicine; Medical Director, Information Technology Services, UW Medicine, Seattle, Washington
  1123. Richard D. Pearson, MD, Professor Emeritus of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia
  1124. Trish M. Perl, MD, MSc, Jay Sanford Professor of Medicine and Chief of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center Dallas, Texas
  1125. Michael A. Pesce, PhD, Professor Emeritus of Pathology and Cell Biology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York
  1126. Brett W. Petersen, MD, MPH, Epidemiology Team Lead, Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, Georgia
  1127. William A. Petri, Jr., MD, PhD, Wade Hampton Frost Professor of Epidemiology and Vice Chair for Research, Department of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia
  1128. Marc A. Pfeffer, MD, PhD, Dzau Professor of Medicine, Harvard Medical School; Senior Physician, Brigham and Womens Hospital, Boston, Massachusetts
  1129. David S. Pisetsky, MD, PhD, Professor of Medicine and Immunology, Duke University School of Medicine, Chief, Rheumatology, VA Medical Center, Durham, North Carolina
  1130. Frank Powell, PhD, Professor of Medicine, University of California, San Diego, School of Medicine, La Jolla, California
  1131. Reed Е. Pyeritz, MD, PhD, Professor of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
  1132. Thomas C. Quinn, MD, MSc, Professor of Medicine and Pathology, Director, Center for Global Health, Johns Hopkins University School of Medicine; Associate Director, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Baltimore, Maryland
  1133. Jai Radhakrishnan, MD, MS, Professor of Medicine, Columbia University Vagelos College of Physicians and Surgeons; Clinical Chief, Division of Nephrology, Columbia University Irving Medical Center, New York, New York
  1134. Jerald Radich, MD, Associate Professor of Medical Oncology, Clinical Research Division, Fred Hutchinson Cancer Research Center and University of Washington School of Medicine, Seattle, Washington
  1135. Petros I. Rafailidis, MD, PhD, MSc, Assistant Professor Internal Medicine-Infectious Diseases, Democritus University of Thrace; Beta University Department of Internal Medicine, University General Hospital of Greece, Alexandroupolis, Greece; Senior Researcher, Alfa Institute of Biomedical Sciences, Athens, Greece
  1136. Ganesh Raghu, MD, Professor of Medicine and Laboratory Medicine (adjunct), University of Washington School of Medicine; Director, Center for Interstitial Lung Diseases, UW Medicine; CoDirector, Scleroderma Clinic, University of Washington Medical Center, Seattle, Washington
  1137. Margaret V. Ragni, MD, MPH, Professor of Medicine, and Clinical Translational Science, University of Pittsburgh School of Medicine; Director, Hemophilia Center of Western Pennsylvania, Pittsburgh, Pennsylvania
  1138. Srinivasa N. Raja, MD, Professor of Anesthesiology, Critical Care Medicine, and Neurology; Director of Pain Research, Division of Pain Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
  1139. S. Vincent Rajkumar, MD, Edward W. and Betty Knight Scripps Professor of Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  1140. James D. Ralston, MD, MPH, Senior Investigator, Kaiser Permanente Washington Health Research Institute, Seattle, Washington
  1141. Stuart H. Ralston, MB ChB, Professor of Rheumatology, University of Edinburgh, Edinburgh, United Kingdom
  1142. Didier Raoult, MD, PhD, Professor, Aix-Marseille Universite, Faculte de Medecine, Chief, Institut Hospitalo-Universitaire Mediterranee-Infection, Marseille, France
  1143. Adam J. Ratner, MD, MPH, Associate Professor of Pediatrics and Microbiology and Chief, Division of Pediatric Infectious Diseases, New York University School of Medicine, New York, New York
  1144. Annette C. Reboli, MD, Dean and Professor of Medicine, Cooper Medical School of Rowan University and Cooper University Hospital, Camden, New Jersey
  1145. K. Rajender Reddy, MD, Ruimy Family President’s Distinguished Professor of Internal Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
  1146. Donald A. Redelmeier, MD, Professor of Medicine, University of Toronto; Canada Research Chair, Medical Decision Science; Senior Scientist, Evaluative Clinical Sciences, Sunnybrook Research Institute; Staff Physician, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
  1147. Susan E. Reef, MD, Medical Epidemiologist, Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia
  1148. John Reilly, MD, Richard D. Krugman Endowed Chair and Dean, School of Medicine, and Vice Chancellor for Health Affairs, University of Colorado School of Medicine, Aurora, Colorado
  1149. Megan E. Reller, MD, PhD, Associate Professor of Medicine, Duke University School of Medicine, Durham, North Carolina
  1150. Neil M. Resnick, MD, Thomas Detre Professor of Medicine and Chief, Division of Geriatric Medicine and Gerontology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
  1151. David B. Reuben, MD, Archstone Professor and Chief, Division of Geriatrics, David, Geffen School of Medicine at UCLA, Los Angeles, California
  1152. Jennifer G. Robinson, MD, MPH, Professor of Epidemiology and Medicine, Director, Prevention Intervention Center, Department of Epidemiology, University of Iowa Carver College of Medicine, Iowa City, Iowa
  1153. Inez Rogatsky, PhD, Professor of Microbiology and Immunology, Weill Cornell Medical College; Senior Scientist, Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, New York
  1154. Joseph G. Rogers, MD, Professor of Medicine, Duke University School of Medicine, Durham, North Carolina
  1155. Jean-Marc Rolain, PharmD, PhD, Professor, Aix-Marseille Universite and Institut Hospitalo-Universitaire Mediterranee Infection, Marseille, France
  1156. Barrett J. Rollins, MD, PhD, Linde Family Professor of Medicine, Dana-Farber Cancer Institute, Brigham & Womens Hospital and Harvard Medical School, Boston, Massachusetts
  1157. Josё R. Romero, MD, Horace C. Cabe Professor of Infectious Diseases, Department of Pediatrics, University of Arkansas for Medical Sciences; Director, Pediatric Infectious Diseases Section, Arkansas Childrens Hospital; Director, Clinical Trials Research, Arkansas Childrens Research Institute, Little Rock, Arkansas
  1158. Karen Rosene-Montella, MD, President, Karen Rosene, LLC; Senior Consultant the Levinson Institute; Professor Emerita of Medicine, Warren Alpert Medical School at Brown University, Providence, Rhode Island
  1159. Philip J. Rosenthal, MD, Professor of Medicine, University of California, San Francisco, School of Medicine, San Francisco, California
  1160. James A. Russell, MD, Professor of Medicine, University of British Columbia, Vancouver, British Columbia
  1161. Anil K. Rustgi, MD, Irving Professor of Medicine, Director, Herbert Irving Comprehensive Cancer Center; Chief, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center Cancer Service, Columbia University Vagelos College of Physicians and Surgeons, New York, New York
  1162. Daniel E. Rusyniak, MD, Professor of Emergency Medicine, Indiana University School of Medicine, Indianapolis, Indiana
  1163. George Sakoulas, MD, Associate Adjunct Professor, Division of Host-Microbe Systems & Therapeutics, University of California, San Diego, School of Medicine, La Jolla, California; Infectious Disease Consultant, Sharp Healthcare, San Diego, California
  1164. Robert A. Salata, MD, STERIS Chair of Excellence in Medicine, Professor and Chairman, Department of Medicine, Case Western Reserve University School of Medicine; Physician-in-Chief, Master Clinician in Infectious Diseases, University Hospitals Cleveland Medical Center, Cleveland, Ohio
  1165. Jane E. Salmon, MD, Collette Kean Research Chair, Hospital for Special Surgery; Professor of Medicine, Weill Cornell Medical College, New York, New York
  1166. Edsel Maurice T. Salvana, MD, DTM&H, Associate Professor of Medicine and Director, Institute of Molecular Biology and Biotechnology, National Institutes of Health, University of the Philippines College of Medicine, Manila, Philippines
  1167. Nanette Santoro, MD, Professor and E. Stewart Taylor Chair, Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, Colorado
  1168. Renato M. Santos, MD, Assistant Professor of Medicine, Emory University School of Medicine, Emory Heart and Vascular Center, Johns Creek, Georgia
  1169. Peter A. Santucci, MD, Professor of Medicine, Loyola University Medical Center, Maywood, Illinois
  1170. Patrice Savard, MD, MSc, Assistant Professor of Microbiology and Immunology, Universite de Montreal; Director, Unite de Prevention, Centre Hospitalier de I’Universite de Montreal, Quebec, Canada
  1171. Michael N. Sawka, PhD, Professor, School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia
  1172. Paul D. Scanlon, MD, Professor of Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  1173. Andrew I. Schafer, MD, Professor of Medicine, Director, Richard T. Silver Center for Myeloproliferative Neoplasms, Weill Cornell Medical College, New York, New York
  1174. William Schaffner, MD, Professor of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee
  1175. W. Michael Scheid, MD, Bayer-Gerald L. Mandell Professor of Infectious Diseases; Professor of Medicine; Clinical Professor of Neurosurgery; David A. Harrison Distinguished Educator, University of Virginia Health System, Charlottesville, Virginia
  1176. Manuel Schiff, MD, PhD, Associate Professor of Pediatrics and Head of Metabolic Unit, Reference Center for Inborn Errors of Metabolism, Robert Debre University Hospital, Paris, France
  1177. Michael L. Schilsky, MD, Professor of Medicine and Surgery, Yale University School of Medicine, New Haven, Connecticut
  1178. Robert T. Schooley, MD, Professor of Medicine, University of California, San Diego, School of Medicine, San Diego, California
  1179. David L. Schriger, MD, MPH, Professor of Emergency Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California
  1180. Lynn M. Schuchter, MD, Professor of Medicine, C. Willard Robinson Professor and Chair of the Division of Hematology-Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
  1181. Sam Schulman, MD, PhD, Professor of Medicine, McMaster University Michael G., DeGroote School of Medicine, Hamilton, Ontario, Canada
  1182. Lawrence B. Schwartz, MD, PhD, Charles and Evelyn Thomas Professor of Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia
  1183. Carlos Seas, MD, MSc, Associate Professor of Medicine, Universidad Peruana Cayetano Heredia; Vice Director, Alexander von Humboldt Tropical Medicine Institute, Attending Physician, Infectious and Tropical Medicine, Hospital National Cayetano Heredia, Lima, Peru
  1184. Steven A. Seifert, MD, Professor of Emergency Medicine, University of New Mexico School of Medicine; Medical Director, New Mexico Poison and Drug Information Center, Albuquerque, New Mexico
  1185. Julian Lawrence Seifter, MD, James G. Haidas Distinguished Chair in Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts
  1186. Duygu Selcen, MD, Professor of Neurology and Pediatrics, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  1187. Carol E. Semrad, MD, Professor of Medicine, University of Chicago Pritzker School of Medicine, Chicago, Illinois
  1188. Harry Shamoon, MD, Professor of Medicine and Senior Associate Dean for Clinical & Translational Research, Albert Einstein College of Medicine; Director, Harold and Muriel Block Institute for Clinical and Translational Research at Einstein and Montefiore, Bronx, New York
  1189. Pamela J. Shaw, DBE, MBBS, MD, Professor of Neurology, Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, United Kingdom
  1190. Beth H. Shaz, MD, Chief Medical and Scientific Officer, New York Blood Center; Adjunct Assistant Professor, Department of Pathology and Cell Biology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York
  1191. Robert L. Sheridan, MD, Professor of Surgery, Harvard Medical School and Massachusetts General Hospital, COL (ret), U.S. Army, Boston, Massachusetts
  1192. Stuart Sherman, MD, Glen A. Lehman Professor of Gastroenterology and Professor of Medicine and Radiology; Clinical Director of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana
  1193. Wun-Ju Shieh, MD, MPH, PhD, Deputy Chief/Medical Officer, Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia
  1194. Michael E. Shy, MD, Professor of Neurology and Pediatrics, University of Iowa, Carver College of Medicine, Iowa City, Iowa
  1195. Ellen Sidransky, MD, Chief, Section of Molecular Neurogenetics, Medical Genetics Branch, NHGRI, National Institutes of Health, Bethesda, Maryland
  1196. Richard M. Siegel, MD, PhD, Clinical Director and Chief, Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland
  1197. Costi D. Sifri, MD, Professor of Medicine and Medical Director, Immunocompromised Infectious Diseases Program, University of Virginia Health System, Charlottesville, Virginia
  1198. Robert F. Siliciano, MD, PhD, Professor of Medicine, Johns Hopkins University School of Medicine; Investigator, Howard Hughes Medical Institute, Baltimore, Maryland
  1199. Michael S. Simberkoff, MD, Professor of Medicine, New York University School of Medicine and Chief of Staff, VA New York Harbor Healthcare, System, New York, New York
  1200. David L. Simel, MD, MHS, Professor of Medicine, Duke University School of Medicine; Chief of Medical Service, Durham Veterans Affairs Medical Center, Durham, North Carolina
  1201. Karl Skorecki, MD, Professor and Dean, Azriel Faculty of Medicine, Bar-Ilan University, Ramat Gan, Israel
  1202. Arthur S. Slutsky, CM, MD, Professor of Medicine, Director, Interdepartmental Division of Critical Care Medicine, University of Toronto; Vice President (Research), St. Michaels Hospital; Keenan Research Centre, Li Ka Shing Knowledge Institute, Toronto, Ontario, Canada
  1203. Eric J. Small, MD, Professor of Medicine, Deputy Director and Chief Scientific Officer, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, School of Medicine, San Francisco, California
  1204. Gerald W. Smetana, MD, Professor of Medicine, Harvard Medical School and Physician, Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, Massachusetts
  1205. Gordon Smith, MD, Professor and Chair of Neurology, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia
  1206. Frederick S. Southwick, MD, Professor of Medicine, University of Florida College of Medicine, Gainesville, Florida
  1207. Allen M. Spiegel, MD, Dean Emeritus and Professor of Medicine, Albert Einstein, College of Medicine, Bronx, New York
  1208. Robert Spiera, MD, Professor of Clinical Medicine, Weill Cornell Medical College; Director, Scleroderma, Vasculitis, & Myositis Center, Hospital for Special Surgery, New York, New York
  1209. Stanley M. Spinola, MD, Professor of Medicine, Microbiology and Immunology, Pathology and Laboratory Medicine and Chair, Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana
  1210. Sally P. Stabler, MD, Professor of Medicine and Cleo Scott & Mitchell Vincent Allen Chair in Hematology Research, University of Colorado School of Medicine, Aurora, Colorado
  1211. Stephanie M. Stanford, PhD, Assistant Professor of Medicine, University of California, San Diego, School of Medicine, La Jolla, California
  1212. Paul Stark, MD, Professor Emeritus of Radiology, University of California, San Diego, School of Medicine; Chief of Cardiothoracic Radiology, VA San Diego Healthcare System, La Jolla, California
  1213. David P. Steensma, MD, Associate Professor of Medicine, Harvard Medical School and Physician, Dana-Farber Cancer Institute, Boston, Massachusetts
  1214. Theodore S. Steiner, MD, Professor and Associate Head, Division of Infectious Diseases, University of British Columbia, Vancouver, British Columbia, Canada
  1215. David S. Stephens, MD, Stephen W. Schwarzmann Distinguished Professor of Medicine and Chair, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia
  1216. David A. Stevens, MD, Professor of Medicine, Stanford University School of Medicine, Stanford, California; President and Principal Investigator, Infectious Diseases Research Laboratory, California Institute for Medical Research, San Jose, California
  1217. Dennis L. Stevens, PhD, MD, Professor of Medicine, University of Washington School of Medicine, Seattle, Washington; Research & Development Service, Veterans Affairs Medical Center, Boise, Idaho
  1218. James K. Stoller, MD, MS, Professor and Chairman, Education Institute, Jean Wall Bennett Professor of Medicine, Samson Global Leadership Endowed Chair, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, Cleveland, Ohio
  1219. John H. Stone, MD, MPH, Professor of Medicine, Harvard Medical School, Director, Clinical Rheumatology, Massachusetts General Hospital, Boston, Massachusetts
  1220. Richard M. Stone, MD, Professor of Medicine, Harvard Medical School; Chief of the Medical Staff, Dana-Farber Cancer Institute, Boston, Massachusetts
  1221. Raymond A. Strikes, MD, MPH, Medical Officer, Immunization Services Division, Centers for Disease Control and Prevention, Atlanta, Georgia
  1222. Edwin P. Su, MD, Associate Professor of Clinical Orthopaedics, Weill Cornell Medical College; Associate Attending Orthopaedic Surgeon, Hospital for Special Surgery, New York, New York
  1223. Roland W. Sutter, MD, MPH&TM, Special Adviser to Director, Polio Eradication Department, World Health Organization, Geneva, Switzerland
  1224. Ronald S. Swerdloff, MD, Professor of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California; Chief, Division of Endocrinology, Metabolism and Nutrition, Harbor-UCLA Medical Center, Senior Investigator, Los Angeles Biomedical Research Institute, Torrance, California
  1225. Heidi Swygard, MD, MPH, Professor of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
  1226. Megan Sykes, MD, Michael J. Friedlander Professor of Medicine, Director, Columbia Center for Translational Immunology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York
  1227. H. Keipp Talbot, MD, MPH, Associate Professor of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee
  1228. Marian Tanofsky-Kraff, PhD, Professor of Medical and Clinical Psychology and of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland
  1229. Susan M. Tarlo, MBBS, Professor of Medicine, University of Toronto; Respiratory Physician, University Health Network, Toronto, Ontario, Canada
  1230. Paul S.Teirstein, MD, Chief of Cardiology; Director, Interventional Cardiology, Scripps Clinic, La Jolla, California
  1231. Sam R. Telford, III, ScD, Professor of Infectious Disease and Global Health, Tufts University School of Veterinary Medicine, North Grafton, Massachusetts
  1232. Rajesh V. Thakker, MD, May Professor of Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
  1233. Judith Therrien, MD, Professor of Medicine, Jewish General Hospital, Montreal, Quebec, Canada
  1234. George R. Thompson, III, MD, Associate Professor of Clinical Medicine, University of California, Davis School of Medicine, Davis, California
  1235. Antonella Tosti, MD, Fredric Brandt Endowed Professor of Dermatology, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida
  1236. Indi Trehan, MD, MPH, DTM&H, Associate Professor of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, Missouri; Executive Director and Medical Director, Lao Friends Hospital for Children, Luang Prabang, Lao Peoples Democratic Republic
  1237. Ronald B. Turner, MD, Professor of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia
  1238. Anthony Michael Valeri, MD, Associate Professor of Medicine, Vagelos College of Physicians and Surgeons; Medical Director, Hemodialysis, Columbia University Irving Medical Center, New York, New York
  1239. John Varga, MD, John and Nancy Hughes Distinguished Professor of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
  1240. Bradley V. Vaughn, MD, Professor of Neurology, University of North Carolina, Chapel Hill, North Carolina
  1241. Alan P. Venook, MD, Professor of Clinical Medicine, University of California, San Francisco, School of Medicine, San Francisco, California
  1242. Joseph G. Verbalis, MD, Professor of Medicine, Georgetown University; Chief, Endocrinology and Metabolism, Georgetown University Hospital, Washington, D.C.
  1243. Ronald G. Victor, MD, Formerly Burns & Allen Professor of Medicine, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California
  1244. Angela Vincent, MBBS, MSc, Emeritus Professor, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
  1245. Tonia L. Vincent, PhD, Professor of Musculoskeletal Biology, Arthritis Research UK Senior Fellow and Consultant Rheumatologist; Director, Arthritis Research UK Centre for Osteoarthritis Pathogenesis, University of Oxford, Oxford, England
  1246. Robert M. Wachter, MD, Holly Smith Professor and Chairman, Department of Medicine, University of California, San Francisco, School of Medicine, San Francisco, California
  1247. Edward H. Wagner, MD, MPH, Director Emeritus, MacColl Center for Health Care Innovation, Group Health Research Institute, Seattle, Washington
  1248. Edward E. Walsh, MD, Professor of Medicine, University of Rochester School of Medicine & Dentistry; Unit Chief, Infectious Diseases, Rochester General Hospital, Rochester, New York
  1249. Thomas J. Walsh, MD, Professor of Medicine, Pediatrics, Microbiology & Immunology and Chief, Infectious Diseases Translational Research Laboratory, Weill Cornell Medical College, New York, New York; Adjunct Professor of Pathology, Johns Hopkins University School of Medicine; Adjunct Professor of Medicine, University of Maryland School of Medicine, Baltimore, Maryland
  1250. Jeremy D. Walston, MD, Raymond and Anna Lublin Professor of Geriatric Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
  1251. Roland B. Walter, MD, PhD, MS, Associate Professor of Medicine, University of Washington School of Medicine and Associate Member, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington
  1252. Christina Wang, MD, Professor of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California; Clinical and Translational Science Institute, Los Angeles Biomedical Research Institute and Division of Endocrinology, Department of Medicine, Harbor-UCLA Medical Center, Torrance, California
  1253. Lorraine B. Ware, MD, Professor of Medicine, Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee
  1254. Cirle A. Warren, MD, Associate Professor of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia
  1255. John T. Watson, MD, MSc, Respiratory Viruses Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
  1256. Thomas J. Weber, MD, Associate Professor of Medicine, Duke University School of Medicine, Durham, North Carolina
  1257. Geoffrey A. Weinberg, MD, Professor of Pediatrics, University of Rochester School of Medicine & Dentistry; Director, Clinical Pediatric Infectious Diseases & Pediatric HIV Program, Golisano Children’s Hospital, University of Rochester Medical Center, Rochester, New York
  1258. David A. Weinstein, MD, MMSc, Professor of Pediatrics, University of Connecticut School of Medicine, Farmington, Connecticut; Director, Glycogen Storage Disease Program, Connecticut Children’s Medical Center, Hartford, Connecticut
  1259. Robert S. Weinstein, MD, Professor of Medicine, University of Arkansas for Medical Sciences; Staff Endocrinologist, Central Arkansas Veterans Health Care System, Little Rock, Arkansas
  1260. Roger D. Weiss, MD, Professor of Psychiatry, Harvard Medical School, Boston, Massachusetts; Chief, Division of Alcohol and Drug Abuse, McLean Hospital, Belmont, Massachusetts
  1261. Roy E. Weiss, MD, PhD, Kathleen & Stanley Glaser Distinguished Chair and Chairman, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida; Esformes Professor Emeritus, Department of Medicine, University of Chicago Pritzker School of Medicine, Chicago, Illinois
  1262. Jeffrey I. Weitz, MD, Professor of Medicine & Biochemistry, McMaster University Michael G. DeGroote School of Medicine; Executive Director, Thrombosis & Atherosclerosis Research Institute, Hamilton, Ontario, Canada
  1263. Richard P. Wenzel, MD, MSc, Professor and Former Chairman, Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia
  1264. Victoria P. Werth, MD, Professor of Dermatology, University of Pennsylvania Perelman School of Medicine; Chief of Dermatology, Corporal Michael J. Crescenz VAMC, Philadelphia, Pennsylvania
  1265. Sterling G. West, MD, Professor of Medicine, University of Colorado School of Medicine, Aurora, Colorado
  1266. A. Clinton White, Jr., MD, Professor of Internal Medicine, University of Texas Medical, Branch, Galveston, Texas
  1267. Christopher J. White, MD, Chairman and Professor of Medicine, Ochsner Clinical School of the University of Queensland, Ochsner Medical Institutions, New Orleans, Louisiana
  1268. Julian White, MBBS, MD, Professor and Head, Toxinology Department, Women’s & Children’s Hospital, North Adelaide, South Australia, Australia
  1269. Perrin С. White, MD, Professor of Pediatrics, University of Texas Southwestern Medical Center; Chief of Endocrinology, Childrens Medical Center, Dallas, Texas
  1270. Richard J. Whitley, MD, Distinguished Professor of Pediatrics, Loeb Eminent Scholar Chair in Pediatrics, Professor of Microbiology, Medicine, and Neurosurgery, Pediatrics, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama
  1271. Michael P. Whyte, MD, Professor of Medicine, Pediatrics, and Genetics, Washington University School of Medicine in St. Louis; Medical-Scientific Director, Center for Metabolic Bone Disease and Molecular Research, Shriners Hospital for Children, St. Louis, Missouri
  1272. Samuel Wiebe, MD, MSc, Professor of Clinical Neurosciences, Community Health Sciences and Pediatrics, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada
  1273. Jeanine P. Wiener-Kronish, MD, Henry Isaiah Dorr Professor of Research and Teaching in Anaesthesia, Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School; Anesthestist-in-Chief, Massachusetts General Hospital, Boston, Massachusetts
  1274. David J. Wilber, MD, George M Eisenberg Professor of Medicine, Loyola University Chicago Stritch School of Medicine; Director, Division of Cardiology, Loyola University Medical Center, Maywood, Illinois
  1275. Beverly Winikoff, MD, MPH, President, Gynuity Health Projects; Professor of Clinical Population and Family Health, Population and Family Health, Columbia University Mailman School of Public Health, New York, New York
  1276. Jane N. Winter, MD, Professor of Medicine, Robert H Lurie Comprehensive Cancer Center and the Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois
  1277. Edward M. Wolin, MD, Professor of Medicine, Albert Einstein College of Medicine; Director, Neuroendocrine Tumor Program, Department of Medical Oncology, Montefiore Einstein Center for Cancer Care, Bronx, New York
  1278. Gary P. Wormser, MD, Professor of Medicine and of Microbiology and Immunology and Pharmacology, New York Medical College; Chief, Division of Infectious Diseases, Valhalla, New York
  1279. Neal S. Young, MD, Chief, Hematology Branch, NHLBI, National Heart, Lung, and Blood Institute, Bethesda, Maryland
  1280. Vincent B. Young, MD, PhD, William Henry Fitzbutler Professor of Internal Medicine/ Infectious Diseases, Professor of Microbiology & Immunology, University of Michigan Medical School, Ann Arbor, Michigan
  1281. William F. Young, Jr., MD, MSc, Professor of Medicine, Tyson Family Endocrinology Clinical Professor, Mayo Clinic College of Medicine and Science, Rochester, Minnesota
  1282. Alan S.L. Yu, MB BChir, Harry Statland and Solon Summerfield Professor, University of Kansas Medical Center; Director, The Kidney Institute, University of Kansas Medical Center, Kansas City, Kansas
  1283. Anita K.M. Zaidi, MBBS, SM, Director, Enteric and Diarrheal Diseases; and Vaccine Development and Surveillance, Bill and Melinda Gates Foundation, Seattle, Washington
  1284. SherifZaki, MD, PhD, Chief, Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia
  1285. Thomas R. Ziegler, MD, Department of Medicine, Division of Endocrinology, Metabolism and Lipids, Emory University School of Medicine, Atlanta, Georgia
  1286. Peter Zimetbaum, MD, Richard and Susan Smith Professor of Cardiovascular Medicine, Harvard Medical School; Associate Chief and Director of Clinical Cardiology, Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts

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Редактор: Искандер Милевски. Дата публикации: 12.11.2024

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